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TissGeneSummary for TP53TG5 |
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Basic gene information | Gene symbol | TP53TG5 |
Gene name | TP53 target 5 | |
Synonyms | C20orf10|CLG01 | |
Cytomap | UCSC genome browser: 20q13.12 | |
Type of gene | protein-coding | |
RefGenes | NM_014477.2, | |
Description | TP53-inducible gene 5 proteinTP53-target gene 5 protein | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
HPRD : 12733 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_TP53TG5 | |
BioGPS: 27296 | ||
Pathway | NCI Pathway Interaction Database: TP53TG5 | |
KEGG: TP53TG5 | ||
REACTOME: TP53TG5 | ||
Pathway Commons: TP53TG5 | ||
Context | iHOP: TP53TG5 | |
ligand binding site mutation search in PubMed: TP53TG5 | ||
UCL Cancer Institute: TP53TG5 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of TP53TG5 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
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GO ID | GO term | PubMed ID |
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TissGeneExp for TP53TG5 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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![]() (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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![]() (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for TP53TG5 |
![]() (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for TP53TG5 |
TissGeneSNV for TP53TG5 |
![]() Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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![]() (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.N96K | KIRC | 7 |
p.N96H | KIRC | 5 |
p.N97D | ESCA | 2 |
p.A222T | SKCM | 1 |
p.S229P | STAD | 1 |
p.K122N | UCEC | 1 |
p.T179I | SKCM | 1 |
p.E98A | PAAD | 1 |
p.P254A | BRCA | 1 |
p.E25* | OV | 1 |
p.T143M | LGG | 1 |
p.A264V | STAD | 1 |
p.R23Q | COAD | 1 |
p.K78N | KIRP | 1 |
p.V133M | COAD | 1 |
p.E141Q | BLCA | 1 |
p.D203N | SKCM | 1 |
p.E25Q | OV | 1 |
p.Q101K | ESCA | 1 |
p.K108R | KIRC | 1 |
p.W271C | CESC | 1 |
p.L62M | STAD | 1 |
p.A245T | PRAD | 1 |
p.N96K | COAD | 1 |
p.R269G | SARC | 1 |
p.R175K | SKCM | 1 |
p.R265T | CESC | 1 |
p.A5V | OV | 1 |
p.W252* | PRAD | 1 |
p.S112Y | THYM | 1 |
p.S75I | BLCA | 1 |
p.P215H | LUAD | 1 |
p.Q18K | ESCA | 1 |
p.R68M | KIRP | 1 |
p.A146V | UCEC | 1 |
p.R241H | SKCM | 1 |
p.R217* | UCEC | 1 |
p.N91Y | LUAD | 1 |
p.E107K | STAD | 1 |
p.S15P | UCEC | 1 |
p.G104R | PRAD | 1 |
p.S230F | BLCA | 1 |
p.R233H | HNSC | 1 |
p.Q95K | ESCA | 1 |
p.A222V | STAD | 1 |
p.V225M | STAD | 1 |
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TissGeneCNV for TP53TG5 |
![]() (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for TP53TG5 |
![]() (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for TP53TG5 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for TP53TG5 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for TP53TG5 |
TissGeneDrug for TP53TG5 |
![]() (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for TP53TG5 |
![]() (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |