TissGDB

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	TissGeneSummary
	TissGeneExp
	TissGene-miRNA
	TissGeneMut: TissGeneSNV, TissGeneCNV, and TissGeneFusions
	TissGeneNet
	TissGeneProg
	TissGeneClin: TissGeneDrug and TissGeneDisease

TissGeneSummary for ANXA1

Gene summary

Basic gene information	Gene symbol	ANXA1
	Gene name	annexin A1
	Synonyms	ANX1\|LPC1
	Cytomap	UCSC genome browser: 9q21.13
	Type of gene	protein-coding
	RefGenes	NM_000700.2,
	Description	annexin I (lipocortin I)annexin-1calpactin IIcalpactin-2chromobindin-9phospholipase A2 inhibitory protein
	Modification date	20141222
dbXrefs	MIM : 151690
	HGNC : HGNC
	Ensembl : ENSG00000135046
	HPRD : 01060
	Vega : OTTHUMG00000020016
Protein	UniProt: go to UniProt's Cross Reference DB Table
Expression	CleanEX: HS_ANXA1
	BioGPS: 301
Pathway	NCI Pathway Interaction Database: ANXA1
	KEGG: ANXA1
	REACTOME: ANXA1
	Pathway Commons: ANXA1
Context	iHOP: ANXA1
	ligand binding site mutation search in PubMed: ANXA1
	UCL Cancer Institute: ANXA1
Assigned class in TissGDB*	C
Included tissue-specific gene expression resources	HPA,GTExHPA,TiGER,GTEx
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx)	Esophagus
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA)	ESCA
Reference showing the relevant tissue of ANXA1
Description by TissGene annotations	Cancer gene TissgsLTS

* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C.

Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez

GO ID	GO term	PubMed ID
GO:0018149	peptide cross-linking	10908733
GO:0030216	keratinocyte differentiation	10908733
GO:0031340	positive regulation of vesicle fusion	2138016
GO:0071385	cellular response to glucocorticoid stimulus	2936963
GO:0018149	peptide cross-linking	10908733
GO:0030216	keratinocyte differentiation	10908733
GO:0031340	positive regulation of vesicle fusion	2138016
GO:0071385	cellular response to glucocorticoid stimulus	2936963

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TissGeneExp for ANXA1

Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)

Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01)

Gene expressions across normal tissues of GTEx data
(GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct)
- Here, we shows the matched tissue types only among our 28 cancer types.

Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)

- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05)

Cancer type	Mean(exp) in tumor	Mean(exp) in matched normal	Log2FC	P-val.	FDR
THCA	3.027982288	1.422309407	1.605672881	7.29E-13	6.73E-12
PRAD	-0.16908942	0.853020196	-1.022109615	4.36E-08	4.55E-07
KIRP	0.842897119	-1.059399756	1.902296875	2.40E-09	2.09E-08
HNSC	3.481402351	5.260993049	-1.779590698	2.04E-06	1.43E-05
KIRC	0.519538785	-0.890068159	1.409606944	1.73E-19	1.31E-18
BRCA	-0.181705952	2.355751066	-2.537457018	9.45E-53	1.12E-50

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TissGene-miRNA for ANXA1

Significantly anti-correlated miRNAs of TissGene across 28 cancer types
(Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016)
(TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21)
(TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16)
(Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25))

Cancer type

miRNA id

miRNA accession

P-val.

Coeff.

# samples

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TissGeneMut for ANXA1

TissGeneSNV for ANXA1

nsSNV counts per each loci.
Different colors of circles represent different cancer types. Circle size denotes number of samples.
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)
* Click on the image to enlarge it in a new window.

Somatic nucleotide variants of TissGene across 28 cancer types
(X-axis: cancer type and Y-axis: % of mutated samples)
The numbers in parentheses are numbers of samples with mutation (nsSNVs).
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)

- nsSNVs sorted by frequency.

AAchange	Cancer type	# samples
p.S27L	BRCA	1
p.R188Q	STAD	1
p.R124C	SKCM	1
p.M1I	UCEC	1
p.P32A	BLCA	1
p.R72Q	ACC	1
p.E148*	BLCA	1
p.V301I	COAD	1
p.R303H	KIRC	1
p.R212K	SKCM	1
p.S173P	BLCA	1
p.K294R	COAD	1
p.M308T	STAD	1
p.R298K	SKCM	1
p.D135V	PAAD	1
p.R234C	UCEC	1
p.A179T	COAD	1
p.A313T	BLCA	1
p.A35V	SARC	1
p.S170*	LUAD	1
p.D167Y	READ	1
p.F221L	PRAD	1
p.E280*	LUSC	1
p.E122*	HNSC	1
p.R144I	READ	1
p.F277L	COAD	1
p.T64A	SKCM	1
p.E17K	SKCM	1
p.R72Q	UCEC	1
p.R303C	LGG	1
p.R124H	UCEC	1
p.P40L	SKCM	1
p.G33R	COAD	1
p.P44L	SKCM	1
p.L104P	PAAD	1
p.P44S	BLCA	1
p.F118Y	SARC	1
p.T132A	HNSC	1
p.R188Q	READ	1
p.R303C	KICH	1
p.V268M	STAD	1
p.M308I	SKCM	1
p.V220M	UCEC	1
p.V108A	LIHC	1
p.E280D	STAD	1
p.I267V	STAD	1
p.I138S	PAAD	1
p.E148K	SKCM	1
p.Q23X	LGG	1

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TissGeneCNV for ANXA1

Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples)
(TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16)

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TissGeneFusions for ANXA1

Fusion genes including TissGene
(ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01)

Database	Src	Cancer type	Sample	Fusion gene	ORF	5'-gene BP	3'-gene BP
Chimerdb3.0	ChiTaRs	NA	CF126160	ANXA1-ARPC3		chr9:75775232	chr12:110873951
Chimerdb3.0	ChiTaRs	NA	CB132862	ANXA1-U2SURP		chr9:75775236	chr3:142769845
Chimerdb3.0	ChiTaRs	NA	BF805488	H2AFY2-ANXA1		chr10:71855431	chr9:75775753
Chimerdb3.0	ChiTaRs	NA	BF873709	ANXA1-MIR548AE2		chr9:75770143	chr16:48400529

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TissGeneNet for ANXA1

Co-expressed gene networks based on protein-protein interaction data (CePIN)
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(PINA2 ppi data)

BRCA (tumor)	BRCA (normal)
ANXA1, SQSTM1, SIRT7, HMGA1, UBC, YWHAZ, SRC, RIPK1, GAPDH, CD4, FPR1, UBE3A, RPA1, OTUB1, PRKCI, PLA2G4A, ANXA5, DLG3, C1orf123, S100A11, ATG4B (tumor)	ANXA1, HMGA1, YWHAQ, UBE2D1, CD4, FPR1, MYL12A, EGFR, KRT8, UBE3A, UNC119, TGM2, FAF1, PLA2G4A, ANXA5, DLG3, C1orf123, S100A11, USP25, DYSF, CSAD (normal)

COAD (tumor)	COAD (normal)
ANXA1, SIRT7, COPS6, CUL5, SUMO2, SRC, CCT7, RIPK1, FPR1, EGFR, KRT8, APBB1, KLHL23, PLA2G4A, ANXA5, DLG3, C1orf123, S100A11, DYSF, PPM1B, USPL1 (tumor)	ANXA1, COPS6, UBC, SRC, CCT7, RIPK1, CD4, NFKBIA, FPR1, MYL12A, RPA1, TGM2, APBB1, KLHL23, PLA2G4A, ANXA5, S100A11, DYSF, CSAD, ATG4B, USPL1 (normal)

HNSC (tumor)	HNSC (normal)
ANXA1, SQSTM1, SIRT7, HMGA1, YWHAZ, SUMO2, KIAA0101, SRC, RIPK1, YWHAQ, UBE2I, UCHL5, TGM2, OTUB1, APBB1, KLHL23, XRCC6, ANXA5, C1orf123, S100A11, PPM1B (tumor)	ANXA1, SQSTM1, SIRT7, UBC, YWHAZ, RIPK1, YWHAQ, CD4, MGMT, KRT8, UCHL5, UNC119, TGM2, OTUB1, APBB1, FAF1, KLHL23, PLA2G4A, S100A11, DYSF, USPL1 (normal)

KICH (tumor)	KICH (normal)
ANXA1, SQSTM1, SIRT7, HMGA1, YWHAZ, IKBKG, RELA, RIPK1, UBE2D1, CD4, UBE2I, NFKBIA, FPR1, MYL12A, KRT8, UCHL5, TRPM7, TGM2, ANXA5, DLG3, USP25 (tumor)	ANXA1, SQSTM1, HMGA1, RELA, SRC, RIPK1, YWHAQ, SUMO1, CD4, NFKBIA, FPR1, MYL12A, MGMT, KRT8, TRPM7, UBE3A, UNC119, TGM2, DLG3, C1orf123, S100A11 (normal)

KIRC (tumor)	KIRC (normal)
ANXA1, SQSTM1, YWHAZ, KIAA0101, RIPK1, YWHAQ, UBE2D1, CD4, UBE2I, NFKBIA, FPR1, MYL12A, KRT8, UCHL5, TRPM7, UNC119, TGM2, OTUB1, FAF1, ANXA5, DLG3 (tumor)	ANXA1, CUL5, UBC, YWHAZ, SUMO2, RIPK1, YWHAQ, UBE2D1, SUMO1, GAPDH, CD4, UBE2I, FPR1, MYL12A, TRPM7, TGM2, APBB1, ANXA5, DLG3, C1orf123, S100A11 (normal)

KIRP (tumor)	KIRP (normal)
ANXA1, CUL5, HMGA1, UBC, YWHAZ, KIAA0101, RIPK1, YWHAQ, UBE2D1, CD4, UBE2I, FPR1, MYL12A, KRT8, UCHL5, TRPM7, RPA1, TGM2, ANXA5, S100A11, DYSF (tumor)	ANXA1, SQSTM1, COPS6, CUL5, YWHAZ, YWHAQ, UBE2I, MYL12A, MGMT, KRT8, TRPM7, TGM2, APBB1, PRKCI, FAF1, ANXA5, DLG3, S100A11, USP25, DYSF, PPM1B (normal)

LIHC (tumor)	LIHC (normal)
ANXA1, COPS6, HMGA1, YWHAZ, SUMO2, SRC, RIPK1, UBE2D1, SUMO1, UBE2I, NFKBIA, FPR1, MYL12A, MGMT, KRT8, APBB1, PRKCI, PLA2G4A, ANXA5, DLG3, S100A11 (tumor)	ANXA1, SIRT7, COPS6, YWHAZ, UBE2D1, SUMO1, CD4, FPR1, MYL12A, MGMT, C14orf1, TGM2, APBB1, PLA2G4A, ANXA5, DLG3, S100A11, USP25, DYSF, ATG4B, USPL1 (normal)

LUAD (tumor)	LUAD (normal)
ANXA1, HMGA1, UBC, YWHAZ, RELA, SRC, RIPK1, YWHAQ, UBE2D1, NFKBIA, FPR1, MYL12A, KRT8, UCHL5, RPA1, FAF1, PLA2G4A, XRCC6, ANXA5, DLG3, S100A11 (tumor)	ANXA1, UBC, SUMO2, UBE2D1, CD4, FPR1, MYL12A, EGFR, C14orf1, UNC119, TGM2, KLHL23, PLA2G4A, ANXA5, DLG3, C1orf123, S100A11, USP25, DYSF, PPM1B, ATG4B (normal)

LUSC (tumor)	LUSC (normal)
ANXA1, HMGA1, UBC, YWHAZ, RELA, RIPK1, YWHAQ, UBE2D1, SUMO1, NFKBIA, FPR1, MYL12A, EGFR, KRT8, RPA1, OTUB1, FAF1, XRCC6, ANXA5, DLG3, S100A11 (tumor)	ANXA1, SIRT7, HMGA1, UBC, YWHAZ, YWHAQ, GAPDH, NFKBIA, MYL12A, MGMT, EGFR, C14orf1, APBB1, PRKCI, FAF1, KLHL23, S100A11, USP25, CSAD, ATG4B, USPL1 (normal)

PRAD (tumor)	PRAD (normal)
ANXA1, SQSTM1, COPS6, CUL5, YWHAZ, SUMO2, RELA, SRC, RIPK1, GAPDH, CD4, UBE2I, FPR1, EGFR, KRT8, TRPM7, PRKCI, KLHL23, XRCC6, ATG4B, USPL1 (tumor)	ANXA1, SQSTM1, SIRT7, HMGA1, KIAA0101, CCT7, RIPK1, GAPDH, CD4, NFKBIA, FPR1, MYL12A, EGFR, TGM2, APBB1, FAF1, PLA2G4A, ANXA5, S100A11, USP25, DYSF (normal)

STAD (tumor)	STAD (normal)
ANXA1, SQSTM1, CUL5, UBC, YWHAZ, SRC, YWHAQ, UBE2D1, CD4, FPR1, MGMT, EGFR, KRT8, UCHL5, C14orf1, PRKCI, FAF1, ANXA5, S100A11, USP25, CSAD (tumor)	ANXA1, UBC, YWHAZ, RELA, SRC, UBE2D1, NFKBIA, FPR1, MYL12A, MGMT, EGFR, UCHL5, UNC119, KLHL23, PLA2G4A, ANXA5, C1orf123, S100A11, USP25, PPM1B, ATG4B (normal)

THCA (tumor)	THCA (normal)
ANXA1, SQSTM1, HMGA1, UBC, YWHAZ, KIAA0101, RELA, YWHAQ, UBE2D1, NFKBIA, FPR1, MYL12A, KRT8, RPA1, PRKCI, ANXA5, S100A11, USP25, DYSF, PPM1B, CSAD (tumor)	ANXA1, HMGA1, YWHAZ, SUMO2, RELA, SRC, YWHAQ, UBE2D1, UBE2I, FPR1, MYL12A, EGFR, UCHL5, UNC119, TGM2, FAF1, PLA2G4A, XRCC6, ANXA5, S100A11, USP25 (normal)

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TissGeneProg for ANXA1

Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image to enlarge it in a new window.

Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.

Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.

Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.

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TissGeneClin for ANXA1

TissGeneDrug for ANXA1

Drug information targeting TissGene
(DrugBank Version 5.0.6, 2017-04-01)

DrugBank ID	Drug name	Drug activity	Drug type	Drug status
DB00288	Amcinonide	Agonist	Small molecule	Approved
DB01234	Dexamethasone	Agonist	Small molecule	Approved\|Investigational\|Vet_approved
DB00741	Hydrocortisone	Agonist	Small molecule	Approved\|Vet_approved

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TissGeneDisease for ANXA1

Disease information associated with TissGene
(DisGeNet, 2016-06-01)

Disease ID	Disease name	# pubmeds	Source
umls:C0596263	Carcinogenesis	15	BeFree
umls:C0006142	Malignant neoplasm of breast	14	BeFree
umls:C0678222	Breast Carcinoma	12	BeFree
umls:C0027627	Neoplasm Metastasis	11	BeFree,CTD_human,RGD
umls:C0007137	Squamous cell carcinoma	9	BeFree,CTD_human,LHGDN
umls:C0376358	Malignant neoplasm of prostate	8	BeFree
umls:C0600139	Prostate carcinoma	8	BeFree
umls:C0178874	Tumor Progression	7	BeFree
umls:C0242379	Malignant neoplasm of lung	4	BeFree
umls:C0524851	Neurodegenerative Disorders	4	BeFree
umls:C0684249	Carcinoma of lung	4	BeFree
umls:C2239176	Liver carcinoma	4	BeFree
umls:C0001418	Adenocarcinoma	3	BeFree,LHGDN
umls:C0004114	Astrocytoma	3	BeFree
umls:C0005684	Malignant neoplasm of urinary bladder	3	BeFree
umls:C0007133	Carcinoma, Papillary	3	BeFree
umls:C0021368	Inflammation	3	LHGDN,RGD
umls:C0024623	Malignant neoplasm of stomach	3	BeFree
umls:C0024667	Animal Mammary Neoplasms	3	CTD_human
umls:C0033578	Prostatic Neoplasms	3	CTD_human,LHGDN
umls:C0042164	Uveitis	3	BeFree,RGD
umls:C0152013	Adenocarcinoma of lung (disorder)	3	BeFree,CTD_human
umls:C0278996	Cancer of Head and Neck	3	BeFree
umls:C0279626	Squamous cell carcinoma of esophagus	3	BeFree,CTD_human
umls:C0699791	Stomach Carcinoma	3	BeFree
umls:C0699885	Carcinoma of bladder	3	BeFree
umls:C1458155	Mammary Neoplasms	3	BeFree,LHGDN
umls:C0002395	Alzheimer's Disease	2	BeFree
umls:C0004364	Autoimmune Diseases	2	BeFree
umls:C0009324	Ulcerative Colitis	2	BeFree
umls:C0009402	Colorectal Carcinoma	2	BeFree
umls:C0010346	Crohn Disease	2	BeFree
umls:C0011854	Diabetes Mellitus, Insulin-Dependent	2	BeFree
umls:C0011860	Diabetes Mellitus, Non-Insulin-Dependent	2	BeFree,GAD
umls:C0014175	Endometriosis	2	BeFree,LHGDN
umls:C0014474	Ependymoma	2	BeFree
umls:C0016667	Fragile X Syndrome	2	BeFree
umls:C0017638	Glioma	2	BeFree
umls:C0019693	HIV Infections	2	BeFree
umls:C0020429	Hyperalgesia	2	RGD
umls:C0020538	Hypertensive disease	2	CTD_human,RGD
umls:C0022116	Ischemia	2	BeFree,RGD
umls:C0024121	Lung Neoplasms	2	BeFree,LHGDN
umls:C0024141	Lupus Erythematosus, Systemic	2	BeFree
umls:C0024198	Lyme Disease	2	BeFree
umls:C0024232	Lymphatic Metastasis	2	BeFree,CTD_human
umls:C0024668	Mammary Neoplasms, Experimental	2	CTD_human,RGD
umls:C0027430	Nasal Polyps	2	BeFree
umls:C0032002	Pituitary Diseases	2	BeFree
umls:C0038454	Cerebrovascular accident	2	BeFree
umls:C0235974	Pancreatic carcinoma	2	BeFree
umls:C0280324	Laryngeal Squamous Cell Carcinoma	2	BeFree
umls:C0282612	Prostatic Intraepithelial Neoplasias	2	LHGDN
umls:C0546837	Malignant neoplasm of esophagus	2	BeFree
umls:C1168327	High-Grade Prostatic Intraepithelial Neoplasia	2	BeFree
umls:C1527249	Colorectal Cancer	2	BeFree
umls:C1709246	Non-Neoplastic Disorder	2	BeFree
umls:C0003873	Rheumatoid Arthritis	1	LHGDN
umls:C0004096	Asthma	1	BeFree
umls:C0005683	Urinary Bladder Calculi (disorder)	1	BeFree
umls:C0005695	Bladder Neoplasm	1	LHGDN
umls:C0006111	Brain Diseases	1	BeFree
umls:C0007107	Malignant neoplasm of larynx	1	BeFree
umls:C0007112	Adenocarcinoma of prostate	1	BeFree
umls:C0007113	Rectal Carcinoma	1	BeFree
umls:C0007115	Malignant neoplasm of thyroid	1	BeFree
umls:C0007134	Renal Cell Carcinoma	1	RGD
umls:C0007138	Carcinoma, Transitional Cell	1	BeFree,LHGDN,RGD
umls:C0007222	Cardiovascular Diseases	1	BeFree
umls:C0007282	Carotid Stenosis	1	BeFree
umls:C0007785	Cerebral Infarction	1	RGD
umls:C0007786	Brain Ischemia	1	RGD
umls:C0007847	Malignant tumor of cervix	1	BeFree
umls:C0009319	Colitis	1	RGD
umls:C0010674	Cystic Fibrosis	1	BeFree
umls:C0011853	Diabetes Mellitus, Experimental	1	RGD
umls:C0014072	Experimental Autoimmune Encephalomyelitis	1	RGD
umls:C0014859	Esophageal Neoplasms	1	BeFree,LHGDN
umls:C0017636	Glioblastoma	1	BeFree
umls:C0019163	Hepatitis B	1	BeFree
umls:C0019196	Hepatitis C	1	BeFree
umls:C0020550	Hyperthyroidism	1	RGD
umls:C0020676	Hypothyroidism	1	RGD
umls:C0021390	Inflammatory Bowel Diseases	1	BeFree
umls:C0021831	Intestinal Diseases	1	BeFree
umls:C0021841	Intestinal Neoplasms	1	BeFree
umls:C0022658	Kidney Diseases	1	CTD_human
umls:C0023055	Laryngeal neoplasm	1	LHGDN
umls:C0023418	leukemia	1	BeFree
umls:C0023443	Hairy Cell Leukemia	1	BeFree
umls:C0023467	Leukemia, Myelocytic, Acute	1	BeFree
umls:C0023893	Liver Cirrhosis, Experimental	1	RGD
umls:C0023895	Liver diseases	1	LHGDN
umls:C0023903	Liver neoplasms	1	BeFree
umls:C0024115	Lung diseases	1	BeFree
umls:C0024299	Lymphoma	1	BeFree
umls:C0024530	Malaria	1	BeFree
umls:C0025202	melanoma	1	BeFree
umls:C0026640	Mouth Neoplasms	1	CTD_human
umls:C0026847	Spinal Muscular Atrophy	1	BeFree
umls:C0026850	Muscular Dystrophy	1	BeFree,LHGDN
umls:C0027055	Myocardial Reperfusion Injury	1	RGD
umls:C0027626	Neoplasm Invasiveness	1	CTD_human
umls:C0027765	nervous system disorder	1	BeFree
umls:C0027814	Neuritis, Autoimmune, Experimental	1	RGD
umls:C0027819	Neuroblastoma	1	BeFree
umls:C0028945	oligodendroglioma	1	BeFree
umls:C0029463	Osteosarcoma	1	BeFree
umls:C0030524	Paratuberculosis	1	BeFree
umls:C0032231	Pleurisy	1	RGD
umls:C0034069	Pulmonary Fibrosis	1	RGD
umls:C0036341	Schizophrenia	1	BeFree
umls:C0036916	Sexually Transmitted Diseases	1	BeFree
umls:C0038354	Stomach Diseases	1	CTD_human
umls:C0038356	Stomach Neoplasms	1	RGD
umls:C0040136	Thyroid Neoplasm	1	LHGDN
umls:C0041296	Tuberculosis	1	BeFree
umls:C0041341	Tuberous Sclerosis	1	BeFree
umls:C0079731	B-Cell Lymphomas	1	BeFree
umls:C0086543	Cataract	1	RGD
umls:C0149925	Small cell carcinoma of lung	1	BeFree
umls:C0151546	Oral Cavity Carcinoma	1	BeFree
umls:C0152018	Esophageal carcinoma	1	BeFree
umls:C0153381	Malignant neoplasm of mouth	1	BeFree
umls:C0153601	Malignant neoplasm of penis	1	BeFree
umls:C0206663	Neuroectodermal Tumor, Primitive	1	BeFree
umls:C0220756	Niemann-Pick Disease, Type C	1	BeFree
umls:C0233794	Memory impairment	1	BeFree
umls:C0235031	Neurologic Symptoms	1	BeFree
umls:C0238348	Squamous cell carcinoma of penis	1	BeFree
umls:C0238461	Anaplastic thyroid carcinoma	1	BeFree
umls:C0267750	Acute peritonitis	1	BeFree
umls:C0278827	Bladder cancer recurrent	1	BeFree
umls:C0279628	Adenocarcinoma Of Esophagus	1	BeFree
umls:C0302592	Cervix carcinoma	1	BeFree
umls:C0333186	Restenosis	1	BeFree
umls:C0338106	Adenocarcinoma of colon	1	BeFree
umls:C0346153	Breast Cancer, Familial	1	BeFree
umls:C0376634	Craniofacial Abnormalities	1	CTD_human
umls:C0476073	Papillary neoplasm	1	BeFree
umls:C0549473	Thyroid carcinoma	1	BeFree
umls:C0585442	Osteosarcoma of bone	1	BeFree
umls:C0595989	Carcinoma of larynx	1	BeFree
umls:C0700095	Central neuroblastoma	1	BeFree
umls:C0740277	Bile duct carcinoma	1	BeFree
umls:C0751396	Well Differentiated Oligodendroglioma	1	BeFree
umls:C0853105	Penis carcinoma	1	BeFree
umls:C0993582	Arthritis, Experimental	1	RGD
umls:C1257930	Mammary Carcinoma, Human	1	BeFree
umls:C1271104	Blood pressure finding	1	GAD
umls:C1272641	Systemic arterial pressure	1	GAD
umls:C1290884	Inflammatory disorder	1	BeFree
umls:C1335110	Oligodendroglial Neoplasm	1	BeFree
umls:C1561535	Creatinine finding	1	GAD
umls:C1561549	Glomerular filtration rate finding	1	GAD
umls:C1621958	Glioblastoma Multiforme	1	BeFree
umls:C1704272	Benign Prostatic Hyperplasia	1	BeFree
umls:C1800706	Idiopathic Pulmonary Fibrosis	1	BeFree,LHGDN
umls:C1848199	X-Linked Lissencephaly	1	BeFree
umls:C2609414	Acute kidney injury	1	RGD
umls:C2931822	Nasopharyngeal carcinoma	1	BeFree
umls:C2937358	Cerebral Hemorrhage	1	RGD
umls:C3160917	Bladder pain syndrome	1	BeFree
umls:C3665346	Unspecified visual loss	1	BeFree