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TissGeneSummary for TEPP |
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Basic gene information | Gene symbol | TEPP |
Gene name | testis, prostate and placenta expressed | |
Synonyms | - | |
Cytomap | UCSC genome browser: 16q21 | |
Type of gene | protein-coding | |
RefGenes | NM_199046.2, NM_199456.2, | |
Description | testis, prostate and placenta-expressed proteintestis/prostate/placenta-expressed protein | |
Modification date | 20141207 | |
dbXrefs | MIM : 610264 | |
HGNC : HGNC | ||
HPRD : 15486 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_TEPP | |
BioGPS: 374739 | ||
Pathway | NCI Pathway Interaction Database: TEPP | |
KEGG: TEPP | ||
REACTOME: TEPP | ||
Pathway Commons: TEPP | ||
Context | iHOP: TEPP | |
ligand binding site mutation search in PubMed: TEPP | ||
UCL Cancer Institute: TEPP | ||
Assigned class in TissGDB* | A | |
Included tissue-specific gene expression resources | HPA,TiGER,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | ProstateTestis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | PRADTGCT | |
Reference showing the relevant tissue of TEPP | TEPP, a new gene specifically expressed in testis, prostate, and placenta and well conserved in chordates. Biochem Biophys Res Commun. 2003 Dec 26;312(4):1209-15. (pmid:14652002) go to articleTEPP, a new gene specifically expressed in testis, prostate, and placenta and well conserved in chordates. Biochem Biophys Res Commun. 2003 Dec 26;312(4):1209-15. (pmid:14652002) go to article | |
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
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GO ID | GO term | PubMed ID |
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TissGeneExp for TEPP |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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![]() (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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![]() (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
KICH | -1.834223927 | -0.155683927 | -1.67854 | 1.11E-08 | 5.87E-08 |
BRCA | -1.603458734 | 0.557189512 | -2.160648246 | 3.66E-32 | 5.43E-31 |
PRAD | -0.842572465 | 0.955221766 | -1.797794231 | 1.30E-11 | 4.08E-10 |
LUSC | -0.13721828 | 1.666995446 | -1.804213725 | 7.80E-10 | 2.71E-09 |
LUAD | 0.30485028 | 1.76359166 | -1.458741379 | 6.49E-06 | 1.95E-05 |
HNSC | -0.660703369 | 0.857745469 | -1.518448837 | 1.71E-06 | 1.21E-05 |
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TissGene-miRNA for TEPP |
![]() (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for TEPP |
TissGeneSNV for TEPP |
![]() Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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![]() (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.R290C | BRCA | 1 |
p.F193L | HNSC | 1 |
p.A77V | UCEC | 1 |
p.A90V | UCEC | 1 |
p.V224A | STAD | 1 |
p.L278M | UCEC | 1 |
p.S286Y | BLCA | 1 |
p.R128H | STAD | 1 |
p.D108N | SKCM | 1 |
p.A135S | UCEC | 1 |
p.P181H | LUAD | 1 |
p.K113Q | TGCT | 1 |
p.E188Q | BLCA | 1 |
p.D67N | UCEC | 1 |
p.T34A | SKCM | 1 |
p.M107I | SKCM | 1 |
p.G214S | STAD | 1 |
p.P40H | COAD | 1 |
p.A90E | LUSC | 1 |
p.Y38* | BLCA | 1 |
p.S259C | HNSC | 1 |
p.L116R | SKCM | 1 |
p.S259Y | BLCA | 1 |
p.R84Q | SKCM | 1 |
p.C253Y | CHOL | 1 |
p.S286C | HNSC | 1 |
p.G198R | PAAD | 1 |
p.W270X | COAD | 1 |
p.A197T | STAD | 1 |
p.C8Y | ESCA | 1 |
p.F248L | STAD | 1 |
p.G141E | SKCM | 1 |
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TissGeneCNV for TEPP |
![]() (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for TEPP |
![]() (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for TEPP |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for TEPP |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for TEPP |
TissGeneDrug for TEPP |
![]() (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for TEPP |
![]() (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0021390 | Inflammatory Bowel Diseases | 1 | BeFree |