TissGeneSummary for ANKRD30B |
Gene summary |
Basic gene information | Gene symbol | ANKRD30B |
Gene name | ankyrin repeat domain 30B | |
Synonyms | NY-BR-1.1 | |
Cytomap | UCSC genome browser: 18p11.21 | |
Type of gene | protein-coding | |
RefGenes | NM_001029862.1, NM_001145029.1, | |
Description | ankyrin repeat domain-containing protein 30Bbreast cancer antigen NY-BR-1.1serologically defined breast cancer antigen NY-BR-1.1 | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000180777 | ||
Vega : OTTHUMG00000178841 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_ANKRD30B | |
BioGPS: 374860 | ||
Pathway | NCI Pathway Interaction Database: ANKRD30B | |
KEGG: ANKRD30B | ||
REACTOME: ANKRD30B | ||
Pathway Commons: ANKRD30B | ||
Context | iHOP: ANKRD30B | |
ligand binding site mutation search in PubMed: ANKRD30B | ||
UCL Cancer Institute: ANKRD30B | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | ||
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of ANKRD30B | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for ANKRD30B |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
THCA | 0.57888604 | -1.168122435 | 1.747008475 | 9.27E-11 | 6.24E-10 |
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TissGene-miRNA for ANKRD30B |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for ANKRD30B |
TissGeneSNV for ANKRD30B |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.F477L | THCA | 2 |
p.A991V | LUAD | 2 |
p.T977M | COAD | 2 |
p.E1360* | UCEC | 2 |
p.E1373K | UCEC | 1 |
p.R1268Q | HNSC | 1 |
p.A376T | HNSC | 1 |
p.P1035T | LGG | 1 |
p.V385F | UCEC | 1 |
p.N681K | HNSC | 1 |
p.F477L | GBM | 1 |
p.Q1265E | HNSC | 1 |
p.A315V | HNSC | 1 |
p.M1128I | LUAD | 1 |
p.D576E | DLBC | 1 |
p.R308G | BRCA | 1 |
p.V64A | LIHC | 1 |
p.S351* | SKCM | 1 |
p.S678F | BLCA | 1 |
p.S1240F | UCEC | 1 |
p.W575* | HNSC | 1 |
p.A1202S | SARC | 1 |
p.T141M | LGG | 1 |
p.E1021D | UCEC | 1 |
p.G312V | LUAD | 1 |
p.Q475* | SKCM | 1 |
p.L1016V | SKCM | 1 |
p.S530P | UCEC | 1 |
p.G605E | SKCM | 1 |
p.D680Y | LUAD | 1 |
p.V64I | UCEC | 1 |
p.L651V | COAD | 1 |
p.D1027H | ESCA | 1 |
p.G959X | THYM | 1 |
p.E521D | HNSC | 1 |
p.S490C | HNSC | 1 |
p.D767H | LUAD | 1 |
p.A395E | LUAD | 1 |
p.A247S | LUAD | 1 |
p.I1058T | PRAD | 1 |
p.L591F | BLCA | 1 |
p.N1345K | PRAD | 1 |
p.E166K | SKCM | 1 |
p.E365K | SKCM | 1 |
p.S626P | UCEC | 1 |
p.S1065I | UCEC | 1 |
p.Q985* | SKCM | 1 |
p.V1228M | LUAD | 1 |
p.E1164K | SKCM | 1 |
p.E498* | OV | 1 |
p.E796D | CESC | 1 |
p.T977M | UVM | 1 |
p.K1046N | SKCM | 1 |
p.G494V | UVM | 1 |
p.H915Y | UCEC | 1 |
p.K986N | UCEC | 1 |
p.R1024I | UCEC | 1 |
p.E289K | PAAD | 1 |
p.C1085F | LUAD | 1 |
p.T302K | LUAD | 1 |
p.S351L | SKCM | 1 |
p.R483* | ESCA | 1 |
p.T602I | LUAD | 1 |
p.Y134D | UCEC | 1 |
p.Q1272H | LUAD | 1 |
p.L102F | SKCM | 1 |
p.Q1018E | BRCA | 1 |
p.K463Q | UCEC | 1 |
p.S402Y | LIHC | 1 |
p.L143V | LUAD | 1 |
p.V1098I | SKCM | 1 |
p.R1034* | BLCA | 1 |
p.P286S | ESCA | 1 |
p.D680G | UCEC | 1 |
p.V1150F | UCEC | 1 |
p.Y590H | LIHC | 1 |
p.M1086I | ESCA | 1 |
p.T804P | KIRC | 1 |
p.P1210T | HNSC | 1 |
p.Q985L | SKCM | 1 |
p.E599V | LUAD | 1 |
p.R290I | UCEC | 1 |
p.F477L | SARC | 1 |
p.H1103Y | GBM | 1 |
p.E961K | SKCM | 1 |
p.R1314* | BLCA | 1 |
p.P286T | ACC | 1 |
p.N100H | HNSC | 1 |
p.L760V | BRCA | 1 |
p.A1153T | UCEC | 1 |
p.L684I | LUAD | 1 |
p.A1141E | LUAD | 1 |
p.P918A | PAAD | 1 |
p.R1314* | SKCM | 1 |
p.A833T | COAD | 1 |
p.D570Y | LUAD | 1 |
p.S574F | PRAD | 1 |
p.E517D | LUAD | 1 |
p.V51F | UCEC | 1 |
p.T291R | LUAD | 1 |
p.R1314X | READ | 1 |
p.L1029S | LIHC | 1 |
p.R1013K | STAD | 1 |
p.H1105P | SKCM | 1 |
p.D486V | UCEC | 1 |
p.E614K | SKCM | 1 |
p.E877D | THYM | 1 |
p.Q1286H | UCEC | 1 |
p.D464Y | UCEC | 1 |
p.A142V | STAD | 1 |
p.P543R | LUAD | 1 |
p.L320M | UCEC | 1 |
p.K1122N | UCEC | 1 |
p.K1135N | BLCA | 1 |
p.L1254I | UCEC | 1 |
p.S1192N | LIHC | 1 |
p.L77I | LUAD | 1 |
p.L209R | ESCA | 1 |
p.W575C | LUAD | 1 |
p.W575C | ACC | 1 |
p.T1136I | LUAD | 1 |
p.S1071F | SKCM | 1 |
p.L1080F | SKCM | 1 |
p.V1217F | COAD | 1 |
p.M1128K | LUAD | 1 |
p.E348K | PAAD | 1 |
p.Q855K | COAD | 1 |
p.T332P | COAD | 1 |
p.R483Q | UVM | 1 |
p.G162V | THYM | 1 |
p.Q1364K | ESCA | 1 |
p.L780F | CESC | 1 |
p.R623K | SKCM | 1 |
p.E289* | LUAD | 1 |
p.C374W | GBM | 1 |
p.Y1112S | LUAD | 1 |
p.T829S | UCEC | 1 |
p.T773N | LUAD | 1 |
p.A208S | LUAD | 1 |
p.A306V | HNSC | 1 |
p.N1066D | LGG | 1 |
p.V1150L | HNSC | 1 |
p.E582Q | BLCA | 1 |
p.D103Y | LUAD | 1 |
p.D1252N | SKCM | 1 |
p.R308C | BLCA | 1 |
p.S660Y | UCEC | 1 |
p.G846D | THYM | 1 |
p.H1179R | SKCM | 1 |
p.S1242I | PCPG | 1 |
p.K664N | UCEC | 1 |
p.Q969* | PAAD | 1 |
p.T736A | UVM | 1 |
p.E537K | HNSC | 1 |
p.E752* | UCEC | 1 |
p.A1124P | LUAD | 1 |
p.Q462E | CESC | 1 |
p.F640L | UCEC | 1 |
p.L298F | HNSC | 1 |
p.G1213R | CESC | 1 |
p.S914P | READ | 1 |
p.K766I | HNSC | 1 |
p.Q841H | UCEC | 1 |
p.I339M | UCEC | 1 |
p.R483Q | BLCA | 1 |
p.E786K | HNSC | 1 |
p.T541I | UCEC | 1 |
p.E796D | COAD | 1 |
p.A893T | UCEC | 1 |
p.E672* | UCEC | 1 |
p.N1345K | PCPG | 1 |
p.E1031K | LUAD | 1 |
p.S510F | UCEC | 1 |
p.T736A | LUAD | 1 |
p.N1068D | LIHC | 1 |
p.E150D | UCEC | 1 |
p.S757R | LUAD | 1 |
p.E387G | UCEC | 1 |
p.D1218E | LUAD | 1 |
p.E1227G | ESCA | 1 |
p.E384K | SKCM | 1 |
p.R118K | LUAD | 1 |
p.E1256K | SKCM | 1 |
p.V522A | BRCA | 1 |
p.R1255K | SKCM | 1 |
p.F477L | COAD | 1 |
p.R341S | THYM | 1 |
p.I426T | LIHC | 1 |
p.Q451E | ESCA | 1 |
p.E633K | SKCM | 1 |
p.L684F | CESC | 1 |
p.K194T | COAD | 1 |
p.E1114* | LUAD | 1 |
p.Q1056P | READ | 1 |
p.G32R | TGCT | 1 |
p.M210I | LUAD | 1 |
p.D570Y | PRAD | 1 |
p.T813A | COAD | 1 |
p.K1089N | LUAD | 1 |
p.E1172K | SARC | 1 |
p.R1023I | UCEC | 1 |
p.K338N | COAD | 1 |
p.A1183V | UCEC | 1 |
p.R341M | THYM | 1 |
p.K338I | SKCM | 1 |
p.R483Q | LGG | 1 |
p.T736A | KIRC | 1 |
p.E1300K | SKCM | 1 |
p.S172N | KIRP | 1 |
p.K1117M | LUAD | 1 |
p.I1118F | UCEC | 1 |
p.G768D | ACC | 1 |
p.L632F | UCEC | 1 |
p.D94H | BRCA | 1 |
p.E87V | LUAD | 1 |
p.A76P | HNSC | 1 |
p.T1156R | UCEC | 1 |
p.E527D | LUAD | 1 |
p.Q1212L | LUAD | 1 |
p.Q597K | SARC | 1 |
p.K686N | LUAD | 1 |
p.E608K | THYM | 1 |
p.M476I | SARC | 1 |
p.L1060F | UCEC | 1 |
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TissGeneCNV for ANKRD30B |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for ANKRD30B |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for ANKRD30B |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for ANKRD30B |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for ANKRD30B |
TissGeneDrug for ANKRD30B |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for ANKRD30B |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |