TissGeneSummary for RBM44 |
Gene summary |
Basic gene information | Gene symbol | RBM44 |
Gene name | RNA binding motif protein 44 | |
Synonyms | - | |
Cytomap | UCSC genome browser: 2q37.3 | |
Type of gene | protein-coding | |
RefGenes | NM_198852.1, NM_001080504.2, | |
Description | RNA-binding motif protein 44RNA-binding protein 44 | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000177483 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_RBM44 | |
BioGPS: 375316 | ||
Pathway | NCI Pathway Interaction Database: RBM44 | |
KEGG: RBM44 | ||
REACTOME: RBM44 | ||
Pathway Commons: RBM44 | ||
Context | iHOP: RBM44 | |
ligand binding site mutation search in PubMed: RBM44 | ||
UCL Cancer Institute: RBM44 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of RBM44 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for RBM44 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for RBM44 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for RBM44 |
TissGeneSNV for RBM44 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.S922L | UCEC | 2 |
p.E1021K | LUAD | 1 |
p.Q96* | LUAD | 1 |
p.D135N | DLBC | 1 |
p.L815H | SKCM | 1 |
p.R919I | UCEC | 1 |
p.A418T | UCEC | 1 |
p.E679K | ACC | 1 |
p.D427Y | LUAD | 1 |
p.S268Y | UCEC | 1 |
p.Q308H | UCEC | 1 |
p.R603S | BRCA | 1 |
p.P988T | LUAD | 1 |
p.Q379* | UCEC | 1 |
p.G1028D | DLBC | 1 |
p.L655P | LUAD | 1 |
p.S381F | SKCM | 1 |
p.E216* | UCEC | 1 |
p.K440T | UCEC | 1 |
p.S1034Y | UCEC | 1 |
p.G20R | SKCM | 1 |
p.D388Y | PRAD | 1 |
p.H673R | UCEC | 1 |
p.V902A | OV | 1 |
p.R483K | LUAD | 1 |
p.T429S | LUAD | 1 |
p.R620H | STAD | 1 |
p.M450I | BRCA | 1 |
p.C229R | UCEC | 1 |
p.T88A | STAD | 1 |
p.L905F | LUAD | 1 |
p.G13R | OV | 1 |
p.Q423R | GBM | 1 |
p.F146L | STAD | 1 |
p.M536L | UCEC | 1 |
p.E273D | STAD | 1 |
p.D249N | READ | 1 |
p.T90P | STAD | 1 |
p.T429A | BLCA | 1 |
p.F709L | THYM | 1 |
p.E369* | UCEC | 1 |
p.E194X | STAD | 1 |
p.L637X | COAD | 1 |
p.Q187H | LUAD | 1 |
p.V144F | CESC | 1 |
p.T438A | LIHC | 1 |
p.W786R | OV | 1 |
p.E68X | COAD | 1 |
p.V548I | GBM | 1 |
p.K281Q | UCEC | 1 |
p.G42S | BRCA | 1 |
p.T494I | HNSC | 1 |
p.T456P | COAD | 1 |
p.S411F | SKCM | 1 |
p.V348I | LUAD | 1 |
p.P51S | LUSC | 1 |
p.S92G | DLBC | 1 |
p.E68* | UCEC | 1 |
p.E194* | STAD | 1 |
p.E1009D | READ | 1 |
p.F146L | SKCM | 1 |
p.D879N | UCEC | 1 |
p.F694S | COAD | 1 |
p.D530Y | LUAD | 1 |
p.A424S | LUAD | 1 |
p.S493C | BLCA | 1 |
p.A209T | STAD | 1 |
p.W786R | PRAD | 1 |
p.P116S | LGG | 1 |
p.S940F | SKCM | 1 |
p.D470N | STAD | 1 |
p.G543E | SKCM | 1 |
p.E142K | LUAD | 1 |
p.S460N | HNSC | 1 |
p.S728L | BLCA | 1 |
p.Q152* | BLCA | 1 |
p.K440N | READ | 1 |
p.V138A | BLCA | 1 |
p.M595I | ESCA | 1 |
p.N56T | UCS | 1 |
p.G297C | LUAD | 1 |
p.S381F | LUAD | 1 |
p.R160I | READ | 1 |
p.S70C | LUAD | 1 |
p.R948L | THYM | 1 |
p.G344R | BLCA | 1 |
p.Q423H | LUAD | 1 |
p.S910T | PRAD | 1 |
p.E91D | READ | 1 |
p.R237C | READ | 1 |
p.H445Y | BRCA | 1 |
p.E711G | SKCM | 1 |
p.T534A | STAD | 1 |
p.G220E | OV | 1 |
p.D387N | SKCM | 1 |
p.D341Y | UCEC | 1 |
p.I425M | KIRP | 1 |
p.L317F | BLCA | 1 |
p.S1034C | KIRC | 1 |
p.S83L | SKCM | 1 |
p.E514K | HNSC | 1 |
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TissGeneCNV for RBM44 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for RBM44 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | FusionScan | UCS | TCGA-N8-A56S-01A | ASB1-RBM44 | Out-of-Frame | chr2:239342336 | chr2:238742639 |
Chimerdb3.0 | FusionScan | LUSC | TCGA-63-A5ML-01A | LRRFIP1-RBM44 | CDS-5'UTR | chr2:238668848 | chr2:238722234 |
TCGAfusionPortal | PRADA | BRCA | TCGA-A7-A26G-01A | RAMP1-RBM44 | CDS-5UTR | Chr2:238768370 | Chr2:238722235 |
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TissGeneNet for RBM44 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for RBM44 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for RBM44 |
TissGeneDrug for RBM44 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for RBM44 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |