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Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory

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TissGeneSummary

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TissGeneExp

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TissGene-miRNA

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TissGeneMut: TissGeneSNV, TissGeneCNV, and TissGeneFusions

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TissGeneNet

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TissGeneProg

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TissGeneClin: TissGeneDrug and TissGeneDisease

TissGeneSummary for LPA
check button Gene summary
Basic gene informationGene symbolLPA
Gene namelipoprotein, Lp(a)
SynonymsAK38|APOA|LP
CytomapUCSC genome browser: 6q26
Type of geneprotein-coding
RefGenesNM_005577.2,
Descriptionantiangiogenic AK38 proteinapo(a)apolipoprotein(a)lp(a)
Modification date20141222
dbXrefs MIM : 152200
HGNC : HGNC
Ensembl : ENSG00000198670
HPRD : 01063
Vega : OTTHUMG00000015956
ProteinUniProt:
go to UniProt's Cross Reference DB Table
ExpressionCleanEX: HS_LPA
BioGPS: 4018
PathwayNCI Pathway Interaction Database: LPA
KEGG: LPA
REACTOME: LPA
Pathway Commons: LPA
ContextiHOP: LPA
ligand binding site mutation search in PubMed: LPA
UCL Cancer Institute: LPA
Assigned class in TissGDB*C
Included tissue-specific gene expression resourcesHPA,GTEx
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx)Liver
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA)LIHC
Reference showing the relevant tissue of LPA
Description by TissGene annotationsTissgsKTS
CNV lost TissGeneKTS
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C.

check button Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez
GO IDGO termPubMed ID


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TissGeneExp for LPA

check button Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
gene exp


check button Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01)
gene isoform exp


check button Gene expressions across normal tissues of GTEx data
(GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct)
- Here, we shows the matched tissue types only among our 28 cancer types.
normal gene exp


check button Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
DEG exp

- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05)
Cancer typeMean(exp) in tumorMean(exp) in matched normalLog2FCP-val.FDR
KICH-2.449060456-0.878364456-1.5706963.25E-059.34E-05
KIRC-1.941640011-0.6734414-1.2681986113.32E-078.80E-07
LIHC4.6444035449.058109544-4.4137061.67E-178.24E-16
LUAD-2.081929283-0.710472387-1.3714568979.11E-126.39E-11
KIRP-2.1022063310.236856169-2.33906257.87E-084.85E-07


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TissGene-miRNA for LPA

check button Significantly anti-correlated miRNAs of TissGene across 28 cancer types
(Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016)
(TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21)
(TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16)
(Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25))
Cancer typemiRNA idmiRNA accessionP-val.Coeff.# samples


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TissGeneMut for LPA
TissGeneSNV for LPA

check button nsSNV counts per each loci.
Different colors of circles represent different cancer types. Circle size denotes number of samples.
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)

* Click on the image to enlarge it in a new window.
SNV lollipop
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check button Somatic nucleotide variants of TissGene across 28 cancer types
(X-axis: cancer type and Y-axis: % of mutated samples)
The numbers in parentheses are numbers of samples with mutation (nsSNVs).
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)
SNV distribution

- nsSNVs sorted by frequency.
AAchangeCancer type# samples
p.R1397*SKCM3
p.E65KSKCM3
p.E1135KSKCM3
p.E1653KSKCM2
p.R1331CSKCM2
p.P1373SSKCM2
p.A1430VSTAD2
p.Q1834HSTAD2
p.C1688*ESCA1
p.V911ICOAD1
p.P1028TLUAD1
p.R1390QSKCM1
p.T1739MOV1
p.P68LSTAD1
p.G1398DACC1
p.P1853SSKCM1
p.W1831*SKCM1
p.E1344GBRCA1
p.P1487SSKCM1
p.A868VLUAD1
p.R37XSKCM1
p.G943RSKCM1
p.S1682IHNSC1
p.R1570SLUAD1
p.A1670VHNSC1
p.R1397QGBM1
p.P1703LSKCM1
p.P1590LLUAD1
p.T1349ALUSC1
p.T1349MOV1
p.E1266KSKCM1
p.M1117ISKCM1
p.T837SLUAD1
p.R1421WESCA1
p.C1720RUCEC1
p.A1491_spliceLUSC1
p.G958*UCEC1
p.T1591ILUAD1
p.G1173ESKCM1
p.E1966KSKCM1
p.G1393ESKCM1
p.Q1622HUCEC1
p.G1621VLUAD1
p.W1123CLUAD1
p.P880HLGG1
p.P1560LSKCM1
p.T1433SLUAD1
p.R820SOV1
p.A1254ETHYM1
p.T1754MUCEC1
p.P1146QPRAD1
p.A977EUCEC1
p.G1727RSKCM1
p.D1774NHNSC1
p.H1978DBLCA1
p.M1231ILUSC1
p.R1840MESCA1
p.S1154FSKCM1
p.Q21KCOAD1
p.P884ALUSC1
p.F1845LCOAD1
p.A868VCOAD1
p.Q1622HLUAD1
p.H1879QLUAD1
p.V1364MTHYM1
p.P1757TLUAD1
p.Y1687FHNSC1
p.N1321SSKCM1
p.M967VLUAD1
p.I916VUCEC1
p.P884TLUAD1
p.P1049SSKCM1
p.D1795GLIHC1
p.Q1386*SKCM1
p.C1228FSKCM1
p.E1599KLUSC1
p.R1464*LGG1
p.C1924FBRCA1
p.E1151KSKCM1
p.D1566NSKCM1
p.T1068ISKCM1
p.Y1312FLUAD1
p.E1599DUCEC1
p.W1343XSKCM1
p.G1186*LUAD1
p.R1422KSKCM1
p.Y1322*LUSC1
p.T1522PSKCM1
p.P1567LREAD1
p.M1195IHNSC1
p.A1976VPAAD1
p.V1070LLUAD1
p.S1191FBLCA1
p.P1246TLUAD1
p.E1583*UCEC1
p.P1362LSKCM1
p.N1219ILUAD1
p.E1091DPAAD1
p.Q933*SARC1
p.A1096VSTAD1
p.V911IKIRP1
p.V1499FLUSC1
p.T1949ISKCM1
p.P918LUCEC1
p.E907KSKCM1
p.R37*HNSC1
p.D1805NSKCM1
p.C1323YBLCA1
p.P1487LSKCM1
p.E932GLUSC1
p.Q1307RSTAD1
p.A18TSKCM1
p.S1886FCOAD1
p.G943RCESC1
p.E1344ASKCM1
p.T1116NLIHC1
p.Q1810HSKCM1
p.T1349MSTAD1
p.E1548XTGCT1
p.W1343*SKCM1
p.E1311KSKCM1
p.H30RSTAD1
p.D27NSKCM1
p.P1531LBLCA1
p.C1688XESCA1
p.R1511XSKCM1
p.G1050ESKCM1
p.P1226SSKCM1
p.R876KSKCM1
p.L2004FSTAD1
p.D1566ALUAD1
p.G2006RLUSC1
p.P410SBRCA1
p.E923KLIHC1
p.R1464QBLCA1
p.D1172NESCA1
p.E1964DSKCM1
p.A1486SLUAD1
p.R1445CSKCM1
p.P1119TLUAD1
p.T1182PSKCM1
p.R1464XUCS1
p.T1185PLUAD1
p.A1980VESCA1
p.R1751KSKCM1
p.D1795GUCEC1
p.A1934DESCA1
p.T45KKIRC1
p.L1798ITHYM1
p.G1072ESKCM1
p.G1727ESKCM1
p.P1269LSKCM1
p.D1392NSKCM1
p.P1497LPRAD1
p.V1701AUCEC1
p.C1323SPCPG1
p.P1492TLUAD1
p.R37*SKCM1
p.G831*KIRC1
p.S1866FSKCM1
p.H30QCESC1
p.G1406ESARC1
p.P1590LSKCM1
p.G1557WLUAD1
p.P1049LSKCM1
p.S852CPAAD1
p.P1538QLUAD1
p.R1177XCOAD1
p.V911ISTAD1
p.R1508QSKCM1
p.W1855*LUAD1
p.A2024DLUAD1
p.N987SLIHC1
p.Q1190*BRCA1
p.E1091KSKCM1
p.Q848KLUAD1
p.H1978YSTAD1
p.K2001ICOAD1
p.A924DSARC1
p.A1733VHNSC1
p.L1253IOV1
p.R37QBRCA1
p.P1112HUCEC1
p.F1791SSKCM1
p.R1692QCESC1
p.G1619SSKCM1
p.C1551FHNSC1
p.T1159MCOAD1
p.Q848KSTAD1
p.E1047KSKCM1
p.P19HKIRP1
p.P878SSKCM1
p.R1100SLGG1
p.T1319SLUAD1
p.R1016LBLCA1
p.G1050WLUSC1
p.P1148SSKCM1
p.Y1503CLUAD1
p.E1977DLUAD1
p.R1647PSKCM1
p.T1484SSKCM1
p.D1452NSKCM1
p.M872ISKCM1
p.T1265MLGG1
p.E1583KSKCM1
p.R1397XSKCM1
p.P1005HLUAD1
p.C1574RHNSC1
p.A924SLUAD1
p.G2035EHNSC1
p.L1690PKIRC1
p.P1542TLUSC1
p.A977EBRCA1
p.G1279RSKCM1
p.G1626DSKCM1
p.G1991ABLCA1
p.R1342KSKCM1
p.T1474PLUAD1
p.E1041KSKCM1
p.S1602CBLCA1
p.R860WSKCM1
p.H1534RLUAD1
p.R1614QOV1
p.E1548KSKCM1
p.R2025LHNSC1
p.R1614WGBM1
p.R1729WREAD1
p.D1167NSKCM1
p.R1570KCOAD1
p.C1579YLUSC1
p.S1623RHNSC1
p.P1226HPAAD1
p.W1123RBLCA1
p.R1464*UCS1
p.S53LBLCA1
p.G2006ESKCM1
p.Q1490HESCA1
p.Q1622LLUAD1
p.T1243PSKCM1
p.R1625QSKCM1
p.I1777TUCEC1
p.Q1718*SKCM1
p.V1252AUCEC1
p.Q26PLUAD1
p.Y885HLUAD1
p.C1551FLUAD1
p.G46*LUSC1
p.T1182IPAAD1
p.V1030FLUAD1
p.R1422SLUSC1
p.V1856LBRCA1
p.V995ALUAD1
p.R1464LHNSC1
p.R1625XCOAD1
p.K2001IUCEC1
p.W1831XSKCM1
p.G1634RSKCM1
p.R1438MESCA1
p.P1208TUCEC1
p.P1269SSKCM1
p.P1428LSKCM1
p.G945*UCEC1
p.P1233LSKCM1
p.A883SLUAD1
p.C1616XSTAD1
p.A912VOV1
p.T888MPRAD1
p.P1094SCOAD1
p.G1406ESKCM1
p.E1375KSKCM1
p.M1117LLUAD1
p.Y1655NSKCM1
p.T1349MBRCA1
p.D1719EREAD1
p.T331MOV1
p.D1167YLGG1
p.E1697*PRAD1
p.A51TKIRP1
p.R1283XCOAD1
p.T1672KLUSC1
p.P1590STHYM1
p.S1597IESCA1
p.Q1559KCOAD1
p.C1616*STAD1
p.R1614LSTAD1
p.R1438STGCT1
p.G1520ESKCM1
p.G1210DSTAD1
p.Y941HKIRP1
p.R1293KSKCM1
p.R974WDLBC1
p.D1501NSKCM1
p.C1168RSTAD1
p.S1528PBLCA1
p.R1511*SKCM1
p.P1368SSKCM1
p.V1051ISKCM1
p.T1349MESCA1
p.V1026LBRCA1


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TissGeneCNV for LPA

check button Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples)
(TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16)
CNV


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TissGeneFusions for LPA

check button Fusion genes including TissGene
(ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01)
DatabaseSrcCancer typeSampleFusion geneORF5'-gene BP3'-gene BP


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TissGeneNet for LPA

check button Co-expressed gene networks based on protein-protein interaction data (CePIN)
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(PINA2 ppi data)
BRCA (tumor)BRCA (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
COAD (tumor)COAD (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
HNSC (tumor)HNSC (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
KICH (tumor)KICH (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
KIRC (tumor)KIRC (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
KIRP (tumor)KIRP (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
LIHC (tumor)LIHC (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
LUAD (tumor)LUAD (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
LUSC (tumor)LUSC (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
PRAD (tumor)PRAD (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
STAD (tumor)STAD (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
bullet pointbullet point
THCA (tumor)THCA (normal)
LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (tumor)LPA, SETDB1, FN1, IGSF21, ELANE, CANX, FBLN5, LRP2, FGB, APOH, CELA1, MMP12 (normal)
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TissGeneProg for LPA

check button Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image to enlarge it in a new window.
survival 1

check button Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image enlarge it in a new window.
survival 2

check button Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image enlarge it in a new window.
survival 3

check button Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image enlarge it in a new window.
survival 4

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TissGeneClin for LPA
TissGeneDrug for LPA

check button Drug information targeting TissGene
(DrugBank Version 5.0.6, 2017-04-01)
DrugBank IDDrug nameDrug activityDrug typeDrug status
DB00513Aminocaproic AcidOtherSmall moleculeApproved|Investigational


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TissGeneDisease for LPA

check button Disease information associated with TissGene
(DisGeNet, 2016-06-01)
Disease IDDisease name# pubmedsSource
umls:C0010068Coronary heart disease52BeFree,CTD_human,GAD,GWASCAT,LHGDN
umls:C1956346Coronary Artery Disease39BeFree,CTD_human,GAD,LHGDN
umls:C0010054Coronary Arteriosclerosis34BeFree
umls:C0004153Atherosclerosis31BeFree,CTD_human,GAD,LHGDN
umls:C0003850Arteriosclerosis29BeFree,LHGDN
umls:C0027051Myocardial Infarction21BeFree,GAD
umls:C0007222Cardiovascular Diseases18BeFree,CTD_human,GAD,LHGDN
umls:C0038454Cerebrovascular accident14BeFree,CTD_human,GAD,LHGDN
umls:C2239176Liver carcinoma9BeFree
umls:C0006142Malignant neoplasm of breast7BeFree
umls:C0029925Ovarian Carcinoma7BeFree
umls:C1140680Malignant neoplasm of ovary7BeFree
umls:C0007102Malignant tumor of colon6BeFree
umls:C0678222Breast Carcinoma6BeFree
umls:C0699790Colon Carcinoma6BeFree
umls:C0011860Diabetes Mellitus, Non-Insulin-Dependent5BeFree,GAD
umls:C0085096Peripheral Vascular Diseases5BeFree,GAD,LHGDN
umls:C0011849Diabetes Mellitus4BeFree,LHGDN
umls:C0020445Hypercholesterolemia, Familial4BeFree
umls:C0022661Kidney Failure, Chronic4BeFree
umls:C0023903Liver neoplasms4BeFree
umls:C0042373Vascular Diseases4BeFree
umls:C0333186Restenosis4BeFree,GAD
umls:C0003873Rheumatoid Arthritis3BeFree
umls:C0020443Hypercholesterolemia3BeFree,CTD_human
umls:C0020538Hypertensive disease3BeFree,LHGDN
umls:C0085580Essential Hypertension3BeFree
umls:C0151744Myocardial Ischemia3BeFree,GAD
umls:C0242339Dyslipidemias3BeFree,GAD
umls:C0948008Ischemic stroke3BeFree
umls:C3272363Ischemic Cerebrovascular Accident3BeFree
umls:C0002395Alzheimer's Disease2BeFree,GAD
umls:C0003507Aortic Valve Stenosis2BeFree
umls:C0007273Carotid Artery Diseases2BeFree,GAD
umls:C0009402Colorectal Carcinoma2BeFree
umls:C0011269Dementia, Vascular2BeFree
umls:C0011854Diabetes Mellitus, Insulin-Dependent2BeFree
umls:C0011884Diabetic Retinopathy2BeFree
umls:C0019693HIV Infections2BeFree
umls:C0020476Hyperlipoproteinemias2BeFree
umls:C0022658Kidney Diseases2BeFree
umls:C0027726Nephrotic Syndrome2BeFree
umls:C0028754Obesity2BeFree,GAD
umls:C0029463Osteosarcoma2BeFree
umls:C0035309Retinal Diseases2BeFree
umls:C0040038Thromboembolism2BeFree,CTD_human
umls:C0155626Acute myocardial infarction2BeFree
umls:C0178874Tumor Progression2BeFree
umls:C0342880Polygenic hypercholesterolemia2BeFree
umls:C0376358Malignant neoplasm of prostate2BeFree
umls:C0585442Osteosarcoma of bone2BeFree
umls:C0596263Carcinogenesis2BeFree
umls:C0600139Prostate carcinoma2BeFree
umls:C0677886Epithelial ovarian cancer2BeFree
umls:C0919267ovarian neoplasm2BeFree
umls:C1704436Peripheral Arterial Diseases2BeFree
umls:C2316810Chronic kidney disease stage 52BeFree
umls:C3542024AORTIC VALVE DISEASE 22BeFree
umls:C0002726Amyloidosis1BeFree
umls:C0002736Amyotrophic Lateral Sclerosis1GAD
umls:C0002875Cooley's anemia1BeFree
umls:C0004096Asthma1GAD
umls:C0005684Malignant neoplasm of urinary bladder1BeFree
umls:C0005779Blood Coagulation Disorders1BeFree
umls:C0007282Carotid Stenosis1LHGDN
umls:C0007766Intracranial Aneurysm1BeFree,GAD
umls:C0007786Brain Ischemia1GAD
umls:C0008495Chorioamnionitis1GAD
umls:C0009375Colonic Neoplasms1BeFree
umls:C0011847Diabetes1BeFree
umls:C0011881Diabetic Nephropathy1LHGDN
umls:C0014072Experimental Autoimmune Encephalomyelitis1BeFree
umls:C0015944Fetal Membranes, Premature Rupture1GAD
umls:C0020517Hypersensitivity1GAD
umls:C0020623Hypolipoproteinemias1CTD_human
umls:C0021775Intermittent Claudication1BeFree
umls:C0022876Premature Obstetric Labor1GAD
umls:C0023434Chronic Lymphocytic Leukemia1BeFree
umls:C0023440Acute Erythroblastic Leukemia1BeFree
umls:C0023487Acute Promyelocytic Leukemia1BeFree
umls:C0024623Malignant neoplasm of stomach1BeFree
umls:C0026769Multiple Sclerosis1BeFree
umls:C0027627Neoplasm Metastasis1BeFree
umls:C0032285Pneumonia1BeFree
umls:C0032914Pre-Eclampsia1GAD
umls:C0034065Pulmonary Embolism1BeFree
umls:C0035078Kidney Failure1BeFree
umls:C0035344Retinopathy of Prematurity1BeFree
umls:C0040053Thrombosis1LHGDN
umls:C0040336Tobacco Use Disorder1GAD
umls:C0042487Venous Thrombosis1CTD_human
umls:C0043459Zellweger Syndrome1BeFree
umls:C0078911AIDS-Associated Nephropathy1BeFree
umls:C0085413Polycystic Kidney, Autosomal Dominant1BeFree
umls:C0151526Premature Birth1GAD
umls:C0151544Gastrointestinal carcinoma1BeFree
umls:C0151650Renal fibrosis1BeFree
umls:C0162291Retinal ischemia1BeFree
umls:C0162871Aortic Aneurysm, Abdominal1BeFree
umls:C0220656Malignant ascites1BeFree
umls:C0333184Calcific stenosis1BeFree
umls:C0342883Cholesteryl Ester Transfer Protein Deficiency1BeFree
umls:C0346429Multiple malignancy1BeFree
umls:C0428791Aortic valve calcification1GWASCAT
umls:C0494463Alzheimer Disease, Late Onset1BeFree
umls:C0524620Metabolic Syndrome X1GAD
umls:C0577631Carotid Atherosclerosis1BeFree
umls:C0685938Malignant neoplasm of gastrointestinal tract1BeFree
umls:C0699791Stomach Carcinoma1BeFree
umls:C0699885Carcinoma of bladder1BeFree
umls:C0751956Acute Cerebrovascular Accidents1BeFree
umls:C0878486Arteriolosclerosis1LHGDN
umls:C0948089Acute Coronary Syndrome1BeFree
umls:C1512981Mammary Tumorigenesis1BeFree
umls:C1520166Xenograft Model1BeFree
umls:C1527249Colorectal Cancer1BeFree
umls:C1559271Non-Malignant Ascites Adverse Event1BeFree
umls:C1800706Idiopathic Pulmonary Fibrosis1BeFree
umls:C1861172Venous Thromboembolism1GAD
umls:C2584620Thrombophilia, hereditary1BeFree
umls:C2919032Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified1GAD
umls:C1835362Lp(A) Deficiency, Congenital0CLINVAR