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| TissGeneSummary for MST1R |
 Gene summary |
| Basic gene information | Gene symbol | MST1R |
| Gene name | macrophage stimulating 1 receptor (c-met-related tyrosine kinase) | |
| Synonyms | CD136|CDw136|PTK8|RON | |
| Cytomap | UCSC genome browser: 3p21.3 | |
| Type of gene | protein-coding | |
| RefGenes | NM_001244937.1, NM_002447.2, | |
| Description | MSP receptorMST1R variant RON30MST1R variant RON62PTK8 protein tyrosine kinase 8RON variant 21RON variant E2E3c-met-related tyrosine kinasemacrophage-stimulating protein receptorp185-Ronsoluble RON variant 1soluble RON variant 2soluble RON vari | |
| Modification date | 20141222 | |
| dbXrefs | MIM : 600168 | |
| HGNC : HGNC | ||
| Ensembl : ENSG00000164078 | ||
| HPRD : 02545 | ||
| Vega : OTTHUMG00000156709 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_MST1R | |
| BioGPS: 4486 | ||
| Pathway | NCI Pathway Interaction Database: MST1R | |
| KEGG: MST1R | ||
| REACTOME: MST1R | ||
| Pathway Commons: MST1R | ||
| Context | iHOP: MST1R | |
| ligand binding site mutation search in PubMed: MST1R | ||
| UCL Cancer Institute: MST1R | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | TiGER,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | ColonProstateStomach | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | COADPRADSTAD | |
| Reference showing the relevant tissue of MST1R | ||
| Description by TissGene annotations | Cancer gene Fused withOncogene | |
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID | GO:0009615 | response to virus | 12676986 | GO:0043406 | positive regulation of MAP kinase activity | 12676986 | GO:0051897 | positive regulation of protein kinase B signaling | 12676986 | GO:0009615 | response to virus | 12676986 | GO:0043406 | positive regulation of MAP kinase activity | 12676986 | GO:0051897 | positive regulation of protein kinase B signaling | 12676986 |
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| TissGeneExp for MST1R |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| KIRC | -3.324199146 | -2.219781091 | -1.104418056 | 2.11E-08 | 6.20E-08 |
| THCA | 0.590416791 | -0.889434057 | 1.479850847 | 2.34E-12 | 1.95E-11 |
| BRCA | 0.792390401 | -0.359383284 | 1.151773684 | 3.53E-10 | 1.32E-09 |
| STAD | 3.200462659 | 1.813028284 | 1.387434375 | 0.00141 | 0.006969429 |
| KICH | -3.098080091 | -1.722260091 | -1.37582 | 0.000828 | 0.001812226 |
| LUSC | 0.501714498 | 1.533353713 | -1.031639216 | 0.000791 | 0.001486922 |
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| TissGene-miRNA for MST1R |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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| TissGeneMut for MST1R |
| TissGeneSNV for MST1R |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.R470C | UCEC | 2 |
| p.P664L | UCEC | 1 |
| p.R845Q | BRCA | 1 |
| p.S1041F | SKCM | 1 |
| p.R696Q | KICH | 1 |
| p.R728W | STAD | 1 |
| p.N1107K | SKCM | 1 |
| p.F232Y | GBM | 1 |
| p.R858C | STAD | 1 |
| p.Q1106E | HNSC | 1 |
| p.R1331Q | SKCM | 1 |
| p.G605V | HNSC | 1 |
| p.R142H | UCEC | 1 |
| p.L1146V | CESC | 1 |
| p.E341K | STAD | 1 |
| p.I1113M | BLCA | 1 |
| p.A131V | UCEC | 1 |
| p.V1143M | LUAD | 1 |
| p.E62K | LUAD | 1 |
| p.S992F | SKCM | 1 |
| p.R1053W | LGG | 1 |
| p.P109S | SKCM | 1 |
| p.D1295N | HNSC | 1 |
| p.G952R | LIHC | 1 |
| p.R1136H | LIHC | 1 |
| p.P1365H | OV | 1 |
| p.S812R | SARC | 1 |
| p.R1289H | UCEC | 1 |
| p.D1295H | BLCA | 1 |
| p.C533S | SARC | 1 |
| p.R582T | BLCA | 1 |
| p.S623N | ESCA | 1 |
| p.Q1343L | LIHC | 1 |
| p.R1212Q | SARC | 1 |
| p.R470S | THYM | 1 |
| p.Q9* | BLCA | 1 |
| p.R631Q | THYM | 1 |
| p.T1082I | ESCA | 1 |
| p.A1144D | COAD | 1 |
| p.R1231C | LUSC | 1 |
| p.S867T | ESCA | 1 |
| p.R504H | THYM | 1 |
| p.P6L | BLCA | 1 |
| p.R1145H | COAD | 1 |
| p.G1385V | THCA | 1 |
| p.R308C | LIHC | 1 |
| p.R1108* | PAAD | 1 |
| p.P525S | SKCM | 1 |
| p.G110E | BLCA | 1 |
| p.Q926K | SKCM | 1 |
| p.R1118C | HNSC | 1 |
| p.D565V | STAD | 1 |
| p.T103M | UCEC | 1 |
| p.T420I | SKCM | 1 |
| p.R1053W | PAAD | 1 |
| p.S1064C | OV | 1 |
| p.E573K | HNSC | 1 |
| p.E1340* | CESC | 1 |
| p.D1027N | BLCA | 1 |
| p.T1261I | BLCA | 1 |
| p.R1331X | THYM | 1 |
| p.V890M | UCEC | 1 |
| p.R142H | THYM | 1 |
| p.S1315F | BLCA | 1 |
| p.C536R | PAAD | 1 |
| p.R500Q | STAD | 1 |
| p.G591C | STAD | 1 |
| p.R617Q | UCEC | 1 |
| p.G1118D | SKCM | 1 |
| p.G1336V | THCA | 1 |
| p.M1371I | CESC | 1 |
| p.R832Q | COAD | 1 |
| p.R1342Q | COAD | 1 |
| p.G1050A | COAD | 1 |
| p.V360M | GBM | 1 |
| p.S1056F | SKCM | 1 |
| p.S1047F | SKCM | 1 |
| p.P115S | PAAD | 1 |
| p.D1295G | UCEC | 1 |
| p.T187N | UCEC | 1 |
| p.R282Q | SKCM | 1 |
| p.V498M | STAD | 1 |
| p.H167P | LUSC | 1 |
| p.E1342Q | CESC | 1 |
| p.G514R | STAD | 1 |
| p.S48G | LUAD | 1 |
| p.G1167D | SKCM | 1 |
| p.S1381L | HNSC | 1 |
| p.H667N | SARC | 1 |
| p.R396Q | CESC | 1 |
| p.L999M | BLCA | 1 |
| p.E639Q | LUSC | 1 |
| p.V345I | DLBC | 1 |
| p.R504H | LAML | 1 |
| p.M551I | PAAD | 1 |
| p.S674F | SKCM | 1 |
| p.E876K | BLCA | 1 |
| p.P615S | SKCM | 1 |
| p.E1121* | BLCA | 1 |
| p.D1235E | STAD | 1 |
| p.R535C | STAD | 1 |
| p.S388F | SKCM | 1 |
| p.P863L | SKCM | 1 |
| p.T606I | LGG | 1 |
| p.V188M | STAD | 1 |
| p.D379N | BRCA | 1 |
| p.A69D | UCEC | 1 |
| p.V977F | OV | 1 |
| p.P855S | LUAD | 1 |
| p.E1055K | HNSC | 1 |
| p.I74V | BLCA | 1 |
| p.D1292H | HNSC | 1 |
| p.E705Q | CESC | 1 |
| p.P99L | SKCM | 1 |
| p.A69V | COAD | 1 |
| p.L965F | HNSC | 1 |
| p.V655I | PRAD | 1 |
| p.A200G | STAD | 1 |
| p.R1030W | COAD | 1 |
| p.P160L | LUAD | 1 |
| p.E1046X | ESCA | 1 |
| p.D951Y | BLCA | 1 |
| p.P358R | CESC | 1 |
| p.V498M | LIHC | 1 |
| p.R1108X | PAAD | 1 |
| p.A889T | BLCA | 1 |
| p.G108S | LUAD | 1 |
| p.Q140* | LUAD | 1 |
| p.D372N | CESC | 1 |
| p.E811K | CESC | 1 |
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| TissGeneCNV for MST1R |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| TissGeneFusions for MST1R |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| Chimerdb3.0 | ChiTaRs | NA | BF772180 | MST1R-SIPA1L3 | chr3:49924847 | chr19:38655221 | |
| Chimerdb3.0 | ChiTaRs | NA | BE932152 | SET-MST1R | chr9:131454279 | chr3:49924891 | |
| TCGAfusionPortal | PRADA | LUAD | TCGA-95-7039-01A | MST1R-FNDC3B | In-frame | Chr3:49932600 | Chr3:171904502 |
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| TissGeneNet for MST1R |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| BRCA (tumor) | BRCA (normal) |
| MST1R, PPP1CC, PPP1CA, UBC, YWHAZ, PLXNB2, RELA, SRC, YWHAQ, JAK2, MST1, YWHAE, FURIN, YWHAB, PIK3R1, YWHAH, SFN, GNB1, PLXNB1, PLXNB3, EPOR (tumor) | MST1R, PPP1CC, YWHAZ, PLCG1, GRB2, PLXNB2, SRC, SHC1, YWHAQ, MST1, YWHAB, PIK3R1, STUB1, AKT1, HSP90AA1, SFN, GAB1, PLXNB1, PLXNB3, EPOR, HYAL2 (normal) |
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| COAD (tumor) | COAD (normal) |
| MST1R, PPP1CA, UBC, YWHAZ, PLCG1, PLXNB2, SRC, SHC1, YWHAQ, MST1, FURIN, YWHAB, YES1, PIK3R1, STUB1, AKT1, SFN, GAB1, PLXNB1, PLXNB3, EPOR (tumor) | MST1R, PPP1CA, UBC, PLCG1, GRB2, PLXNB2, YWHAQ, JAK2, MST1, FURIN, YWHAB, YES1, PIK3R1, STUB1, AKT1, SFN, GNB1, GAB1, PLXNB1, EPOR, HYAL2 (normal) |
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| HNSC (tumor) | HNSC (normal) |
| MST1R, PPP1CC, PPP1CA, YWHAZ, GRB2, PLXNB2, RELA, SRC, SHC1, YWHAQ, JAK2, CBL, FURIN, YWHAB, YES1, PIK3R1, STUB1, SFN, PLXNB1, EPOR, HYAL2 (tumor) | MST1R, PPP1CC, PPP1CA, UBC, PLCG1, GRB2, PLXNB2, RELA, SRC, SHC1, JAK2, HSPA8, CBL, YWHAB, YES1, HSP90AA1, SFN, GNB1, PLXNB1, PLXNB3, HYAL2 (normal) |
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| KICH (tumor) | KICH (normal) |
| MST1R, PPP1CA, PLCG1, PLXNB2, RELA, SRC, SHC1, JAK2, MST1, YWHAE, HSPA8, CBL, FURIN, STUB1, AKT1, YWHAH, SFN, GNB1, GAB1, PLXNB3, EPOR (tumor) | MST1R, PPP1CC, PPP1CA, UBC, YWHAZ, GRB2, PLXNB2, RELA, SHC1, JAK2, YWHAE, HSPA8, CBL, FURIN, PIK3R1, AKT1, HSP90AA1, YWHAH, SFN, GNB1, HYAL2 (normal) |
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| KIRC (tumor) | KIRC (normal) |
| MST1R, UBC, YWHAZ, GRB2, PLXNB2, RELA, SRC, SHC1, YWHAQ, MST1, HSPA8, FURIN, YWHAB, PIK3R1, AKT1, YWHAH, SFN, GNB1, PLXNB3, EPOR, HYAL2 (tumor) | MST1R, PPP1CC, PLCG1, PLXNB2, RELA, SRC, YWHAQ, JAK2, MST1, YWHAE, HSPA8, CBL, FURIN, YES1, PIK3R1, AKT1, SFN, PLXNB1, PLXNB3, EPOR, HYAL2 (normal) |
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| KIRP (tumor) | KIRP (normal) |
| MST1R, PPP1CC, YWHAZ, PLCG1, RELA, SRC, SHC1, YWHAQ, MST1, HSPA8, FURIN, YES1, PIK3R1, AKT1, HSP90AA1, YWHAH, SFN, PLXNB1, PLXNB3, EPOR, HYAL2 (tumor) | MST1R, PPP1CC, YWHAZ, PLCG1, PLXNB2, RELA, SRC, MST1, YWHAE, HSPA8, CBL, FURIN, YWHAB, AKT1, HSP90AA1, SFN, GAB1, PLXNB1, PLXNB3, EPOR, HYAL2 (normal) |
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| LIHC (tumor) | LIHC (normal) |
| MST1R, YWHAZ, PLCG1, PLXNB2, SRC, YWHAQ, JAK2, MST1, YWHAE, CBL, FURIN, YWHAB, AKT1, HSP90AA1, YWHAH, SFN, GNB1, GAB1, PLXNB1, PLXNB3, HYAL2 (tumor) | MST1R, YWHAZ, PLXNB2, SRC, SHC1, YWHAQ, JAK2, MST1, CBL, FURIN, YWHAB, YES1, PIK3R1, AKT1, HSP90AA1, YWHAH, SFN, GNB1, GAB1, PLXNB3, EPOR (normal) |
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| LUAD (tumor) | LUAD (normal) |
| MST1R, PPP1CC, PPP1CA, YWHAZ, PLCG1, PLXNB2, SRC, YWHAQ, MST1, YWHAE, HSPA8, CBL, FURIN, YWHAB, YES1, STUB1, GNB1, GAB1, PLXNB1, EPOR, HYAL2 (tumor) | MST1R, PPP1CC, UBC, PLXNB2, RELA, SRC, YWHAQ, JAK2, MST1, YWHAE, YES1, STUB1, AKT1, HSP90AA1, YWHAH, SFN, GNB1, GAB1, PLXNB1, PLXNB3, HYAL2 (normal) |
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| LUSC (tumor) | LUSC (normal) |
| MST1R, PPP1CC, PPP1CA, YWHAZ, GRB2, PLXNB2, SRC, YWHAQ, JAK2, MST1, YWHAE, HSPA8, CBL, FURIN, YWHAB, AKT1, HSP90AA1, GAB1, PLXNB1, PLXNB3, EPOR (tumor) | MST1R, PPP1CC, PPP1CA, YWHAZ, PLXNB2, RELA, SRC, SHC1, YWHAQ, JAK2, MST1, YWHAE, FURIN, STUB1, HSP90AA1, SFN, GNB1, GAB1, PLXNB3, EPOR, HYAL2 (normal) |
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| PRAD (tumor) | PRAD (normal) |
| MST1R, PPP1CC, PPP1CA, UBC, GRB2, PLXNB2, RELA, SRC, SHC1, YWHAQ, JAK2, MST1, YWHAE, HSPA8, FURIN, STUB1, YWHAH, SFN, GNB1, PLXNB1, PLXNB3 (tumor) | MST1R, PPP1CC, PPP1CA, PLCG1, SRC, SHC1, YWHAQ, JAK2, MST1, YWHAE, HSPA8, CBL, PIK3R1, AKT1, HSP90AA1, YWHAH, SFN, GNB1, GAB1, PLXNB1, EPOR (normal) |
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| STAD (tumor) | STAD (normal) |
| MST1R, PPP1CA, PLCG1, GRB2, PLXNB2, SRC, SHC1, YWHAQ, MST1, YWHAE, HSPA8, CBL, FURIN, YWHAB, PIK3R1, YWHAH, SFN, GNB1, GAB1, PLXNB1, PLXNB3 (tumor) | MST1R, PPP1CA, YWHAZ, PLCG1, PLXNB2, RELA, SRC, YWHAQ, JAK2, HSPA8, CBL, YES1, PIK3R1, YWHAH, SFN, GNB1, GAB1, PLXNB1, PLXNB3, EPOR, HYAL2 (normal) |
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| THCA (tumor) | THCA (normal) |
| MST1R, PPP1CC, UBC, PLCG1, RELA, YWHAQ, JAK2, MST1, YWHAE, HSPA8, CBL, FURIN, STUB1, AKT1, HSP90AA1, YWHAH, SFN, GAB1, PLXNB3, EPOR, HYAL2 (tumor) | MST1R, PPP1CC, YWHAZ, PLXNB2, RELA, SRC, SHC1, YWHAQ, MST1, YWHAE, CBL, YWHAB, YES1, PIK3R1, HSP90AA1, YWHAH, SFN, GNB1, GAB1, PLXNB1, HYAL2 (normal) |
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| TissGeneProg for MST1R |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| TissGeneClin for MST1R |
| TissGeneDrug for MST1R |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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| TissGeneDisease for MST1R |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0007131 | Non-Small Cell Lung Carcinoma | 6 | BeFree |
| umls:C0178874 | Tumor Progression | 6 | BeFree |
| umls:C0009402 | Colorectal Carcinoma | 5 | BeFree |
| umls:C0006142 | Malignant neoplasm of breast | 4 | BeFree |
| umls:C0024623 | Malignant neoplasm of stomach | 4 | BeFree |
| umls:C0027627 | Neoplasm Metastasis | 4 | BeFree |
| umls:C0242379 | Malignant neoplasm of lung | 4 | BeFree |
| umls:C0596263 | Carcinogenesis | 4 | BeFree |
| umls:C0684249 | Carcinoma of lung | 4 | BeFree |
| umls:C0699791 | Stomach Carcinoma | 4 | BeFree |
| umls:C0001418 | Adenocarcinoma | 3 | BeFree,LHGDN |
| umls:C0235974 | Pancreatic carcinoma | 3 | BeFree |
| umls:C0346647 | Malignant neoplasm of pancreas | 3 | BeFree |
| umls:C0376358 | Malignant neoplasm of prostate | 3 | BeFree |
| umls:C0600139 | Prostate carcinoma | 3 | BeFree |
| umls:C0678222 | Breast Carcinoma | 3 | BeFree |
| umls:C1527249 | Colorectal Cancer | 3 | BeFree |
| umls:C2239176 | Liver carcinoma | 3 | BeFree |
| umls:C0001430 | Adenoma | 2 | BeFree,LHGDN |
| umls:C0007102 | Malignant tumor of colon | 2 | BeFree |
| umls:C0007134 | Renal Cell Carcinoma | 2 | BeFree,LHGDN |
| umls:C0009324 | Ulcerative Colitis | 2 | BeFree,LHGDN |
| umls:C0009375 | Colonic Neoplasms | 2 | BeFree,LHGDN |
| umls:C0010346 | Crohn Disease | 2 | BeFree,LHGDN |
| umls:C0024121 | Lung Neoplasms | 2 | BeFree |
| umls:C0024299 | Lymphoma | 2 | BeFree |
| umls:C0026769 | Multiple Sclerosis | 2 | BeFree,LHGDN |
| umls:C0029925 | Ovarian Carcinoma | 2 | BeFree |
| umls:C0033578 | Prostatic Neoplasms | 2 | BeFree |
| umls:C0699790 | Colon Carcinoma | 2 | BeFree |
| umls:C1261473 | Sarcoma | 2 | BeFree |
| umls:C1458155 | Mammary Neoplasms | 2 | BeFree,LHGDN |
| umls:C0005684 | Malignant neoplasm of urinary bladder | 1 | BeFree |
| umls:C0005695 | Bladder Neoplasm | 1 | BeFree |
| umls:C0006413 | Burkitt Lymphoma | 1 | BeFree |
| umls:C0007115 | Malignant neoplasm of thyroid | 1 | BeFree |
| umls:C0007137 | Squamous cell carcinoma | 1 | BeFree |
| umls:C0009404 | Colorectal Neoplasms | 1 | LHGDN |
| umls:C0011065 | Cessation of life | 1 | LHGDN |
| umls:C0014070 | Encephalomyelitis | 1 | LHGDN |
| umls:C0014072 | Experimental Autoimmune Encephalomyelitis | 1 | BeFree |
| umls:C0014175 | Endometriosis | 1 | BeFree,LHGDN |
| umls:C0014867 | Esophageal Varices | 1 | BeFree |
| umls:C0017638 | Glioma | 1 | BeFree |
| umls:C0019693 | HIV Infections | 1 | BeFree |
| umls:C0021390 | Inflammatory Bowel Diseases | 1 | GAD |
| umls:C0023418 | leukemia | 1 | BeFree |
| umls:C0027765 | nervous system disorder | 1 | BeFree |
| umls:C0029463 | Osteosarcoma | 1 | CTD_human |
| umls:C0030354 | Papilloma | 1 | BeFree |
| umls:C0032927 | Precancerous Conditions | 1 | BeFree |
| umls:C0036341 | Schizophrenia | 1 | GAD |
| umls:C0042769 | Virus Diseases | 1 | BeFree |
| umls:C0079744 | Diffuse Large B-Cell Lymphoma | 1 | BeFree |
| umls:C0149678 | Epstein-Barr Virus Infections | 1 | BeFree |
| umls:C0149925 | Small cell carcinoma of lung | 1 | BeFree |
| umls:C0206687 | Carcinoma, Endometrioid | 1 | BeFree |
| umls:C0206754 | Neuroendocrine Tumors | 1 | BeFree |
| umls:C0242488 | Acute Lung Injury | 1 | LHGDN |
| umls:C0346255 | Oncocytoma, renal | 1 | BeFree |
| umls:C0549473 | Thyroid carcinoma | 1 | BeFree |
| umls:C0566602 | Primary sclerosing cholangitis | 1 | BeFree |
| umls:C0686619 | Secondary malignant neoplasm of lymph node | 1 | BeFree |
| umls:C0699885 | Carcinoma of bladder | 1 | BeFree |
| umls:C0860207 | Drug-Induced Liver Injury | 1 | CTD_human |
| umls:C0877373 | Advanced cancer | 1 | BeFree |
| umls:C0919267 | ovarian neoplasm | 1 | LHGDN |
| umls:C0949541 | Hurthle Cell Tumor | 1 | BeFree |
| umls:C1112160 | Gastrooesophageal cancer | 1 | BeFree |
| umls:C1140680 | Malignant neoplasm of ovary | 1 | BeFree |
| umls:C1153706 | Endometrial adenocarcinoma | 1 | BeFree |
| umls:C1168401 | Squamous cell carcinoma of the head and neck | 1 | BeFree |
| umls:C1266042 | Chromophobe Renal Cell Carcinoma | 1 | BeFree |
| umls:C1301034 | Pancreatic intraepithelial neoplasia | 1 | BeFree |
| umls:C1333064 | Classical Hodgkin's Lymphoma | 1 | BeFree |
| umls:C1368683 | Epithelioma | 1 | BeFree |
| umls:C1512981 | Mammary Tumorigenesis | 1 | BeFree |
| umls:C1518171 | Malignant Conversion | 1 | BeFree |
| umls:C1569637 | Adenocarcinoma, Endometrioid | 1 | BeFree |
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