TissGeneSummary for FAM135B |
Gene summary |
Basic gene information | Gene symbol | FAM135B |
Gene name | family with sequence similarity 135, member B | |
Synonyms | C8ORFK32 | |
Cytomap | UCSC genome browser: 8q24.23 | |
Type of gene | protein-coding | |
RefGenes | NM_015912.3, | |
Description | protein FAM135B | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000147724 | ||
HPRD : 14230 | ||
Vega : OTTHUMG00000149864 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_FAM135B | |
BioGPS: 51059 | ||
Pathway | NCI Pathway Interaction Database: FAM135B | |
KEGG: FAM135B | ||
REACTOME: FAM135B | ||
Pathway Commons: FAM135B | ||
Context | iHOP: FAM135B | |
ligand binding site mutation search in PubMed: FAM135B | ||
UCL Cancer Institute: FAM135B | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | TiGER,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | BrainTestis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | GBM,LGGTGCT | |
Reference showing the relevant tissue of FAM135B | ||
Description by TissGene annotations | Protective TissGene in OS Cancer gene Have significant anti-correlated miRNA Fused withTSGene |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for FAM135B |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
LUSC | -3.179276024 | -1.914885828 | -1.264390196 | 1.58E-14 | 9.08E-14 |
BLCA | -2.853875198 | 0.411724802 | -3.2656 | 3.29E-06 | 8.41E-05 |
THCA | -2.883906599 | -1.869625243 | -1.014281356 | 1.08E-08 | 5.36E-08 |
STAD | -1.695495264 | 0.850457861 | -2.545953125 | 1.99E-07 | 4.71E-06 |
COAD | -2.640647668 | 1.746563871 | -4.387211538 | 7.62E-19 | 1.86E-16 |
ESCA | -2.175028787 | 1.055043941 | -3.230072727 | 0.000535 | 0.009595484 |
HNSC | -3.069389886 | -1.987036398 | -1.082353488 | 6.85E-05 | 0.000323113 |
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TissGene-miRNA for FAM135B |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
THYM | hsa-miR-31-5p | MIMAT0000089 | 0.0048 | -0.26 | 122 |
LUAD | hsa-miR-31-5p | MIMAT0000089 | 0.024 | -0.3 | 60 |
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TissGeneMut for FAM135B |
TissGeneSNV for FAM135B |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.R1211Q | SKCM | 3 |
p.D1284N | SKCM | 3 |
p.S657F | SKCM | 3 |
p.H92Y | SKCM | 3 |
p.S1073F | SKCM | 3 |
p.S645R | STAD | 3 |
p.M1345I | SKCM | 3 |
p.G1252E | SKCM | 3 |
p.D1192N | SKCM | 3 |
p.P427S | SKCM | 2 |
p.E481* | LUAD | 2 |
p.E567K | SKCM | 2 |
p.L648M | LUSC | 2 |
p.H491Y | SKCM | 2 |
p.E902K | SKCM | 2 |
p.Q285H | LUSC | 2 |
p.R256C | SKCM | 2 |
p.L359P | LUAD | 2 |
p.D1287N | SKCM | 2 |
p.S221F | SKCM | 2 |
p.G1169E | SKCM | 2 |
p.P563L | SKCM | 2 |
p.S1059F | SKCM | 2 |
p.S11L | SKCM | 2 |
p.D157N | SKCM | 2 |
p.E614K | SKCM | 2 |
p.M470I | SKCM | 2 |
p.A548S | KIRC | 1 |
p.P1065S | SKCM | 1 |
p.G1150E | SKCM | 1 |
p.P1128T | KIRC | 1 |
p.P417L | LUSC | 1 |
p.G1379S | SKCM | 1 |
p.L1033V | ESCA | 1 |
p.A700V | HNSC | 1 |
p.A49T | STAD | 1 |
p.D653H | LUAD | 1 |
p.A418E | HNSC | 1 |
p.Q508* | SKCM | 1 |
p.R136Q | SKCM | 1 |
p.P541L | CESC | 1 |
p.G742S | STAD | 1 |
p.D787N | UCS | 1 |
p.L22I | ESCA | 1 |
p.E1029K | LIHC | 1 |
p.Y1125N | LUSC | 1 |
p.K804N | LUAD | 1 |
p.S165P | SKCM | 1 |
p.N490T | SKCM | 1 |
p.G619E | CESC | 1 |
p.Q602K | LUSC | 1 |
p.N920K | LUAD | 1 |
p.R70Q | UCEC | 1 |
p.W318* | SKCM | 1 |
p.E281K | SKCM | 1 |
p.R242Q | COAD | 1 |
p.P436S | SKCM | 1 |
p.S387I | LUAD | 1 |
p.R1193G | LUAD | 1 |
p.N84H | HNSC | 1 |
p.T1281S | LUAD | 1 |
p.R719Q | LUAD | 1 |
p.E280K | HNSC | 1 |
p.S1274Y | ESCA | 1 |
p.E734K | SKCM | 1 |
p.R1232W | UCEC | 1 |
p.I408M | LUAD | 1 |
p.G619E | SKCM | 1 |
p.P1065T | UCEC | 1 |
p.K634N | ESCA | 1 |
p.G983C | LUAD | 1 |
p.E1394K | SKCM | 1 |
p.E289Q | CESC | 1 |
p.E223K | LUAD | 1 |
p.E1163* | LUAD | 1 |
p.S1226P | STAD | 1 |
p.S1046P | READ | 1 |
p.Y1235N | LUAD | 1 |
p.R892M | LUSC | 1 |
p.A418G | LUAD | 1 |
p.G850W | LUAD | 1 |
p.V1386L | LUAD | 1 |
p.P1249H | STAD | 1 |
p.M100I | SKCM | 1 |
p.P828L | SKCM | 1 |
p.R1289H | HNSC | 1 |
p.V531L | UCEC | 1 |
p.R711W | UCEC | 1 |
p.G731V | LUAD | 1 |
p.P549L | HNSC | 1 |
p.S11L | CESC | 1 |
p.K1107M | CESC | 1 |
p.Q522H | ESCA | 1 |
p.R345Q | SKCM | 1 |
p.R589K | SKCM | 1 |
p.T940M | UCEC | 1 |
p.R1363Q | ESCA | 1 |
p.T7A | UCEC | 1 |
p.V261E | ESCA | 1 |
p.F352L | ESCA | 1 |
p.R719Q | SKCM | 1 |
p.L937V | STAD | 1 |
p.K16T | COAD | 1 |
p.N1365K | LUSC | 1 |
p.Q508* | LUSC | 1 |
p.E729D | UCEC | 1 |
p.E936K | UCEC | 1 |
p.E1390K | SKCM | 1 |
p.R719* | GBM | 1 |
p.L1280M | THYM | 1 |
p.K1178N | UCEC | 1 |
p.L1116V | READ | 1 |
p.R884C | HNSC | 1 |
p.F159L | HNSC | 1 |
p.P296S | SKCM | 1 |
p.E475D | LUAD | 1 |
p.H258N | SKCM | 1 |
p.R678K | READ | 1 |
p.S135R | LUAD | 1 |
p.Y1096H | HNSC | 1 |
p.R1317P | HNSC | 1 |
p.P891S | LUSC | 1 |
p.S606F | LUAD | 1 |
p.P863S | SKCM | 1 |
p.V1030A | SKCM | 1 |
p.S1274F | SKCM | 1 |
p.P637T | LUAD | 1 |
p.E1163K | LGG | 1 |
p.A86S | HNSC | 1 |
p.L1228I | LUAD | 1 |
p.G1169E | HNSC | 1 |
p.V1311A | SKCM | 1 |
p.E515K | SKCM | 1 |
p.R77W | ACC | 1 |
p.D411Y | HNSC | 1 |
p.K561T | ESCA | 1 |
p.Q522H | UCEC | 1 |
p.G1252V | LUSC | 1 |
p.H980L | LUAD | 1 |
p.D306Y | HNSC | 1 |
p.Q1269H | UCEC | 1 |
p.H662Y | BLCA | 1 |
p.L460V | BLCA | 1 |
p.G810V | HNSC | 1 |
p.V450I | UCEC | 1 |
p.D306N | LUSC | 1 |
p.E1050D | LUAD | 1 |
p.S680L | SKCM | 1 |
p.S1046F | LUAD | 1 |
p.P417S | LUSC | 1 |
p.Q1097* | SKCM | 1 |
p.Q1069H | UCEC | 1 |
p.D1085N | LUSC | 1 |
p.L335I | STAD | 1 |
p.G817S | LUAD | 1 |
p.E1131K | SKCM | 1 |
p.I4M | HNSC | 1 |
p.T333S | SKCM | 1 |
p.T617N | ESCA | 1 |
p.R1289C | PRAD | 1 |
p.M314I | SKCM | 1 |
p.T1300R | LUAD | 1 |
p.V695F | HNSC | 1 |
p.D583N | DLBC | 1 |
p.A171S | BRCA | 1 |
p.T371A | KIRP | 1 |
p.K905R | KIRP | 1 |
p.E497K | SKCM | 1 |
p.E1130D | ESCA | 1 |
p.R184H | BRCA | 1 |
p.R253Q | LUAD | 1 |
p.S805N | SKCM | 1 |
p.A237T | STAD | 1 |
p.V1366M | LUAD | 1 |
p.N1375K | LUAD | 1 |
p.E1130K | SKCM | 1 |
p.L1174P | HNSC | 1 |
p.G621R | SKCM | 1 |
p.R539K | SKCM | 1 |
p.L1116V | ESCA | 1 |
p.Y216H | STAD | 1 |
p.G598V | LUAD | 1 |
p.P754L | SKCM | 1 |
p.S11* | LUAD | 1 |
p.Y27C | LUSC | 1 |
p.E481K | SKCM | 1 |
p.P144L | HNSC | 1 |
p.S472C | COAD | 1 |
p.G1248A | HNSC | 1 |
p.P842S | SKCM | 1 |
p.R136Q | COAD | 1 |
p.L1296P | COAD | 1 |
p.E79K | SKCM | 1 |
p.L1228H | LUAD | 1 |
p.L612H | LUSC | 1 |
p.S606F | SKCM | 1 |
p.P417L | SKCM | 1 |
p.E1344K | SKCM | 1 |
p.A899V | LUSC | 1 |
p.V1386L | LUSC | 1 |
p.R1156W | STAD | 1 |
p.P848L | SKCM | 1 |
p.H994Q | SKCM | 1 |
p.A49P | LUAD | 1 |
p.R589K | HNSC | 1 |
p.K305N | SARC | 1 |
p.G952S | SKCM | 1 |
p.G586E | SKCM | 1 |
p.L179F | LUAD | 1 |
p.V972A | HNSC | 1 |
p.H169Y | STAD | 1 |
p.R256H | LUAD | 1 |
p.T319N | KIRC | 1 |
p.E1018D | COAD | 1 |
p.S959L | SKCM | 1 |
p.G1165R | LUAD | 1 |
p.G542C | LUSC | 1 |
p.D1287E | LUAD | 1 |
p.E515X | SKCM | 1 |
p.S995F | SKCM | 1 |
p.T137K | LIHC | 1 |
p.R25K | SKCM | 1 |
p.R145Q | UCEC | 1 |
p.H328N | UCEC | 1 |
p.E1105Q | HNSC | 1 |
p.V8I | ESCA | 1 |
p.H1140Y | SKCM | 1 |
p.L911F | LUAD | 1 |
p.V344I | UCS | 1 |
p.E475D | STAD | 1 |
p.T988N | LUAD | 1 |
p.F1397L | UCEC | 1 |
p.S1046Y | LUAD | 1 |
p.R264W | PAAD | 1 |
p.P427L | LUAD | 1 |
p.W240L | LUSC | 1 |
p.Q954K | OV | 1 |
p.V531L | HNSC | 1 |
p.R701Q | SKCM | 1 |
p.P960S | LUAD | 1 |
p.R1289L | HNSC | 1 |
p.K853N | STAD | 1 |
p.R711G | LUAD | 1 |
p.S684P | HNSC | 1 |
p.F156L | DLBC | 1 |
p.T520I | UCEC | 1 |
p.R701X | UCS | 1 |
p.D685N | SKCM | 1 |
p.S1218Y | UCS | 1 |
p.P708A | LUAD | 1 |
p.R1289H | KIRP | 1 |
p.Q51* | UCEC | 1 |
p.K305N | KIRC | 1 |
p.S645N | HNSC | 1 |
p.R25I | BLCA | 1 |
p.D800N | SKCM | 1 |
p.A103S | BRCA | 1 |
p.Y1404D | STAD | 1 |
p.R948S | BLCA | 1 |
p.T118M | PAAD | 1 |
p.R538K | HNSC | 1 |
p.D660Y | STAD | 1 |
p.Q151K | BLCA | 1 |
p.R1363* | UCEC | 1 |
p.E756Q | LUAD | 1 |
p.M494I | LUSC | 1 |
p.S455F | SKCM | 1 |
p.R565T | KIRC | 1 |
p.H897Y | SKCM | 1 |
p.E1087K | SKCM | 1 |
p.R1289S | HNSC | 1 |
p.E223Q | BLCA | 1 |
p.T1259I | SKCM | 1 |
p.G586R | SKCM | 1 |
p.P549T | LUAD | 1 |
p.E734D | SKCM | 1 |
p.F1044Y | HNSC | 1 |
p.T118M | SARC | 1 |
p.R1380X | SKCM | 1 |
p.M315I | CESC | 1 |
p.P406L | STAD | 1 |
p.T137M | COAD | 1 |
p.S1114G | HNSC | 1 |
p.S222* | ESCA | 1 |
p.G26E | BLCA | 1 |
p.R77Q | MESO | 1 |
p.I83L | LUAD | 1 |
p.E98K | SKCM | 1 |
p.P389L | PRAD | 1 |
p.L592I | LIHC | 1 |
p.Q29K | LUSC | 1 |
p.E1131K | HNSC | 1 |
p.K1103* | LUAD | 1 |
p.S645R | SKCM | 1 |
p.E1394D | UCEC | 1 |
p.G1401E | UCEC | 1 |
p.Q954P | CESC | 1 |
p.H601Q | LUSC | 1 |
p.Y1236H | STAD | 1 |
p.E273* | HNSC | 1 |
p.G928C | LUSC | 1 |
p.G6E | SKCM | 1 |
p.F352I | LUSC | 1 |
p.N447K | STAD | 1 |
p.P891L | SKCM | 1 |
p.G1075R | SKCM | 1 |
p.R457G | KICH | 1 |
p.T765N | LUAD | 1 |
p.S770F | UCEC | 1 |
p.F1392S | OV | 1 |
p.T311M | LUAD | 1 |
p.K881* | BRCA | 1 |
p.E1087K | BLCA | 1 |
p.E650* | SKCM | 1 |
p.W402* | SKCM | 1 |
p.D306H | HNSC | 1 |
p.K1159R | SKCM | 1 |
p.S1152N | SKCM | 1 |
p.S1226L | SKCM | 1 |
p.S11L | COAD | 1 |
p.H238R | UCEC | 1 |
p.L148M | LUAD | 1 |
p.L1398V | BLCA | 1 |
p.A783S | LUSC | 1 |
p.L648M | LUAD | 1 |
p.R77Q | PRAD | 1 |
p.A836G | GBM | 1 |
p.V989A | THCA | 1 |
p.N19K | PAAD | 1 |
p.D787N | BRCA | 1 |
p.E515* | SKCM | 1 |
p.R25T | LUSC | 1 |
p.F259S | GBM | 1 |
p.D555N | LUAD | 1 |
p.I946M | PRAD | 1 |
p.A1017E | LUAD | 1 |
p.S1213_splice | UCEC | 1 |
p.R242X | ESCA | 1 |
p.S165L | SKCM | 1 |
p.F1187I | SKCM | 1 |
p.P774H | HNSC | 1 |
p.G1138E | SKCM | 1 |
p.Q1061H | READ | 1 |
p.L124W | HNSC | 1 |
p.K1101Q | UCS | 1 |
p.R242* | ESCA | 1 |
p.D1085Y | LUAD | 1 |
p.M132R | SKCM | 1 |
p.E517K | SKCM | 1 |
p.V12L | OV | 1 |
p.T311M | UCEC | 1 |
p.Q1097X | SKCM | 1 |
p.L1116V | SKCM | 1 |
p.S435R | ESCA | 1 |
p.L207R | STAD | 1 |
p.G1110R | SKCM | 1 |
p.G850E | SKCM | 1 |
p.T7P | HNSC | 1 |
p.Q29H | LIHC | 1 |
p.S1297I | LUAD | 1 |
p.F429V | UCEC | 1 |
p.W240L | UCEC | 1 |
p.R380W | PAAD | 1 |
p.R719* | HNSC | 1 |
p.E208K | SKCM | 1 |
p.F1392S | LUAD | 1 |
p.R678K | SKCM | 1 |
p.W402X | SKCM | 1 |
p.E1029D | UCEC | 1 |
p.P131T | LUAD | 1 |
p.G215W | UCEC | 1 |
p.P267Q | HNSC | 1 |
p.E223K | SKCM | 1 |
p.G820R | LUSC | 1 |
p.V972L | LUSC | 1 |
p.A251G | LUAD | 1 |
p.E667K | SKCM | 1 |
p.L1350Q | LUAD | 1 |
p.L359R | LUAD | 1 |
p.K620M | HNSC | 1 |
p.E1100* | UCEC | 1 |
p.G731* | LUAD | 1 |
p.A773V | UCEC | 1 |
p.T940M | LUAD | 1 |
p.P740S | PRAD | 1 |
p.A574V | SKCM | 1 |
p.P1314S | LUAD | 1 |
p.S607T | SKCM | 1 |
p.D787E | SKCM | 1 |
p.C641S | ESCA | 1 |
p.H15N | LUAD | 1 |
p.E729K | SKCM | 1 |
p.S329F | SKCM | 1 |
p.W240C | LUAD | 1 |
p.A278V | SKCM | 1 |
p.Q320K | LUAD | 1 |
p.E665K | SKCM | 1 |
p.A103T | UCEC | 1 |
p.Q357H | SKCM | 1 |
p.N209K | UCEC | 1 |
p.H1146D | LUSC | 1 |
p.D446N | PAAD | 1 |
p.R892G | OV | 1 |
p.R760Q | ACC | 1 |
p.E1086K | BLCA | 1 |
p.C518F | HNSC | 1 |
p.L22F | SKCM | 1 |
p.V127L | SKCM | 1 |
p.D108H | LUSC | 1 |
p.L1361F | SKCM | 1 |
p.I1209L | LUAD | 1 |
p.N1257K | SKCM | 1 |
p.S581C | HNSC | 1 |
p.D1358N | SKCM | 1 |
p.P82R | LUSC | 1 |
p.T183N | LUAD | 1 |
p.L937F | LUAD | 1 |
p.R1289G | LUSC | 1 |
p.L359R | BLCA | 1 |
p.H1368Y | SKCM | 1 |
p.R31L | LUSC | 1 |
p.A1343E | PAAD | 1 |
p.F1305L | SKCM | 1 |
p.S811P | THCA | 1 |
p.D108N | ESCA | 1 |
p.E1018Q | HNSC | 1 |
p.S684C | LUSC | 1 |
p.D787H | SKCM | 1 |
p.I654N | SKCM | 1 |
p.Q1298K | UCS | 1 |
p.H1146Q | LUSC | 1 |
p.G542C | LUAD | 1 |
p.A604V | HNSC | 1 |
p.R1325S | LUAD | 1 |
p.R701* | UCS | 1 |
p.A1324D | LGG | 1 |
p.P716S | BLCA | 1 |
p.G599E | SKCM | 1 |
p.F1292I | LUAD | 1 |
p.L22R | LUAD | 1 |
p.R701Q | BRCA | 1 |
p.K789N | LUSC | 1 |
p.E712K | SKCM | 1 |
p.E1163X | READ | 1 |
p.E625V | HNSC | 1 |
p.Y28C | STAD | 1 |
p.S1213G | UCEC | 1 |
p.V67M | UCEC | 1 |
p.R539K | HNSC | 1 |
p.G742S | SKCM | 1 |
p.H724Y | SARC | 1 |
p.V695I | COAD | 1 |
p.D102V | BLCA | 1 |
p.E577D | KIRP | 1 |
p.Y76F | LUAD | 1 |
p.E1197K | SKCM | 1 |
p.D787N | HNSC | 1 |
p.K358N | SKCM | 1 |
p.D910Y | UCEC | 1 |
p.G483V | LUAD | 1 |
p.N1375S | SKCM | 1 |
p.F1292S | LUAD | 1 |
p.S646F | SKCM | 1 |
p.E544* | PAAD | 1 |
p.V133G | STAD | 1 |
p.R1230Q | SKCM | 1 |
p.E577K | SKCM | 1 |
p.L460I | BLCA | 1 |
p.V476F | ACC | 1 |
p.R31* | SKCM | 1 |
p.A796D | SKCM | 1 |
p.R1230Q | READ | 1 |
p.S120N | LUAD | 1 |
p.R31Q | SKCM | 1 |
p.F1057I | SKCM | 1 |
p.L1157M | BLCA | 1 |
p.L454I | HNSC | 1 |
p.R701Q | STAD | 1 |
p.G50W | LUAD | 1 |
p.T1360A | STAD | 1 |
p.H932P | LUAD | 1 |
p.E668K | SKCM | 1 |
p.D399N | UCEC | 1 |
p.P153S | LUSC | 1 |
p.G922V | LUAD | 1 |
p.Q840H | LUSC | 1 |
p.R701Q | UCEC | 1 |
p.P1065A | BLCA | 1 |
p.V993I | UCEC | 1 |
p.T488S | LUSC | 1 |
p.D1137N | BLCA | 1 |
p.G188C | LUAD | 1 |
p.A1356V | HNSC | 1 |
p.E664K | SKCM | 1 |
p.S222X | ESCA | 1 |
p.E689Q | SKCM | 1 |
p.W697L | HNSC | 1 |
p.G674R | LUAD | 1 |
p.E544X | PAAD | 1 |
p.P871S | LUSC | 1 |
p.S803N | STAD | 1 |
p.S312P | UCEC | 1 |
p.N428Y | HNSC | 1 |
p.A128S | LIHC | 1 |
p.V113A | HNSC | 1 |
p.R970I | COAD | 1 |
p.L327M | LUSC | 1 |
p.Y216N | BLCA | 1 |
p.M132I | LUAD | 1 |
p.Q24E | BLCA | 1 |
p.Q854E | COAD | 1 |
p.S2F | HNSC | 1 |
p.A917V | SKCM | 1 |
p.K305E | BRCA | 1 |
p.S693C | COAD | 1 |
p.D583Y | READ | 1 |
p.Q1315R | CESC | 1 |
p.V713A | LUSC | 1 |
p.G1168E | SKCM | 1 |
p.L815I | ESCA | 1 |
p.L829R | STAD | 1 |
p.E289K | HNSC | 1 |
p.L1207H | STAD | 1 |
p.S1297C | LUSC | 1 |
p.R1211Q | COAD | 1 |
p.A350V | STAD | 1 |
p.G621E | SKCM | 1 |
p.S1012F | SKCM | 1 |
p.G420E | SKCM | 1 |
p.T988P | SKCM | 1 |
p.K305N | ACC | 1 |
p.V12I | LUAD | 1 |
p.P1052H | LUSC | 1 |
p.M1328I | LUAD | 1 |
p.G731L | LUAD | 1 |
p.S222* | LUSC | 1 |
p.V450A | STAD | 1 |
p.P1249S | LUAD | 1 |
p.T1191M | LGG | 1 |
p.H1337Y | HNSC | 1 |
p.Q996R | UCEC | 1 |
p.F89L | HNSC | 1 |
p.S1046P | UCEC | 1 |
p.S503L | BRCA | 1 |
p.R703S | HNSC | 1 |
p.R242* | BRCA | 1 |
p.E1133K | UCEC | 1 |
p.G824V | HNSC | 1 |
p.T1021S | LUAD | 1 |
p.S162Y | STAD | 1 |
p.L1207I | UCEC | 1 |
p.P543L | LUAD | 1 |
p.D787Y | KIRC | 1 |
p.H150Y | SKCM | 1 |
p.P427S | LUAD | 1 |
p.K1357N | ESCA | 1 |
p.S741R | BLCA | 1 |
p.H258Y | SKCM | 1 |
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TissGeneCNV for FAM135B |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for FAM135B |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | TopHat-Fusion | LUAD | TCGA-86-7955-01A | EXT1-FAM135B | CDS-5'UTR | chr8:118830673 | chr8:139409895 |
Chimerdb3.0 | TopHat-Fusion | LUAD | TCGA-86-7955-01A | EXT1-FAM135B | CDS-5'UTR | chr8:118830673 | chr8:139403060 |
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TissGeneNet for FAM135B |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for FAM135B |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for FAM135B |
TissGeneDrug for FAM135B |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for FAM135B |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0007137 | Squamous cell carcinoma | 1 | BeFree |
umls:C0029456 | Osteoporosis | 1 | GAD |