TissGeneSummary for CPXCR1 |
Gene summary |
Basic gene information | Gene symbol | CPXCR1 |
Gene name | CPX chromosome region, candidate 1 | |
Synonyms | CT77 | |
Cytomap | UCSC genome browser: Xq21.3 | |
Type of gene | protein-coding | |
RefGenes | NM_001184771.1, NM_033048.5, | |
Description | CPX chromosomal region candidate gene 1 proteincancer/testis antigen 77 | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000147183 | ||
HPRD : 06474 | ||
Vega : OTTHUMG00000021950 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_CPXCR1 | |
BioGPS: 53336 | ||
Pathway | NCI Pathway Interaction Database: CPXCR1 | |
KEGG: CPXCR1 | ||
REACTOME: CPXCR1 | ||
Pathway Commons: CPXCR1 | ||
Context | iHOP: CPXCR1 | |
ligand binding site mutation search in PubMed: CPXCR1 | ||
UCL Cancer Institute: CPXCR1 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of CPXCR1 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
Top |
TissGeneExp for CPXCR1 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
Top |
TissGene-miRNA for CPXCR1 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
Top |
TissGeneMut for CPXCR1 |
TissGeneSNV for CPXCR1 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.G215E | SKCM | 2 |
p.T29K | LUAD | 2 |
p.A164S | LUAD | 2 |
p.Q293L | DLBC | 1 |
p.R230C | READ | 1 |
p.N18K | STAD | 1 |
p.N50K | HNSC | 1 |
p.K174R | ACC | 1 |
p.R230H | STAD | 1 |
p.S150I | LUAD | 1 |
p.P141T | LUAD | 1 |
p.K116N | STAD | 1 |
p.R81* | LUAD | 1 |
p.Y177H | SKCM | 1 |
p.R133* | STAD | 1 |
p.F277L | GBM | 1 |
p.R98G | ESCA | 1 |
p.R234M | LUAD | 1 |
p.Q163* | LUSC | 1 |
p.E88Q | HNSC | 1 |
p.A12T | UCEC | 1 |
p.S235Y | LUSC | 1 |
p.L153I | STAD | 1 |
p.F187L | UCEC | 1 |
p.A193V | COAD | 1 |
p.R230C | LUAD | 1 |
p.R228I | HNSC | 1 |
p.R133* | SKCM | 1 |
p.R201M | LUAD | 1 |
p.L208H | STAD | 1 |
p.A12V | LIHC | 1 |
p.K224E | COAD | 1 |
p.E45D | LUAD | 1 |
p.E191D | HNSC | 1 |
p.R133* | OV | 1 |
p.V265A | LUSC | 1 |
p.D108A | PAAD | 1 |
p.H103Y | BRCA | 1 |
p.C180Y | LIHC | 1 |
p.P207H | LUSC | 1 |
p.R234S | LUAD | 1 |
p.E191K | SKCM | 1 |
p.H203L | STAD | 1 |
p.S200* | LUAD | 1 |
p.Y3* | STAD | 1 |
p.P4T | LUAD | 1 |
p.R81X | COAD | 1 |
p.F285Y | LGG | 1 |
p.R234M | UCEC | 1 |
p.D37N | SKCM | 1 |
p.A121V | BRCA | 1 |
p.R111I | COAD | 1 |
p.H103R | LUAD | 1 |
p.K99X | STAD | 1 |
p.Q93H | LUAD | 1 |
p.Q243P | BLCA | 1 |
p.R81* | STAD | 1 |
p.H154N | LUSC | 1 |
p.A56S | BLCA | 1 |
p.P105H | LUSC | 1 |
p.P97A | LUAD | 1 |
p.K216T | UCEC | 1 |
p.H190Q | LUAD | 1 |
p.G115E | SKCM | 1 |
p.D37A | LGG | 1 |
p.R149K | CESC | 1 |
p.L208F | LUAD | 1 |
p.R234I | LUAD | 1 |
p.I280M | LUAD | 1 |
p.R175* | UCEC | 1 |
p.Q65R | DLBC | 1 |
p.V173A | COAD | 1 |
p.R131H | COAD | 1 |
p.M40I | SKCM | 1 |
p.E68K | SKCM | 1 |
p.R198G | LUAD | 1 |
p.A12V | COAD | 1 |
p.K99* | STAD | 1 |
p.Q43P | BLCA | 1 |
p.E210V | COAD | 1 |
p.V265G | ESCA | 1 |
p.Y288C | LUAD | 1 |
p.R197I | COAD | 1 |
p.E73K | SKCM | 1 |
p.S295* | HNSC | 1 |
p.G252C | PRAD | 1 |
p.C296W | LUAD | 1 |
p.M212I | ESCA | 1 |
p.G282E | KIRC | 1 |
p.I267N | SKCM | 1 |
p.D30H | HNSC | 1 |
p.L257S | SKCM | 1 |
p.N272H | UCEC | 1 |
p.S200L | UCEC | 1 |
Top |
TissGeneCNV for CPXCR1 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
Top |
TissGeneFusions for CPXCR1 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Top |
TissGeneNet for CPXCR1 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
Top |
TissGeneProg for CPXCR1 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Top |
TissGeneClin for CPXCR1 |
TissGeneDrug for CPXCR1 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
TissGeneDisease for CPXCR1 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0038356 | Stomach Neoplasms | 1 | GAD |
umls:C0152415 | Ankyloglossia | 1 | BeFree |