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TissGeneSummary for TIPIN |
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Basic gene information | Gene symbol | TIPIN |
Gene name | TIMELESS interacting protein | |
Synonyms | - | |
Cytomap | UCSC genome browser: 15q22.31 | |
Type of gene | protein-coding | |
RefGenes | NM_001289986.1, NM_017858.2, | |
Description | CSM3 homologTIMELESS-interacting protein | |
Modification date | 20141207 | |
dbXrefs | MIM : 610716 | |
HGNC : HGNC | ||
HPRD : 16917 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_TIPIN | |
BioGPS: 54962 | ||
Pathway | NCI Pathway Interaction Database: TIPIN | |
KEGG: TIPIN | ||
REACTOME: TIPIN | ||
Pathway Commons: TIPIN | ||
Context | iHOP: TIPIN | |
ligand binding site mutation search in PubMed: TIPIN | ||
UCL Cancer Institute: TIPIN | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | TiGER,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | BladderTestis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | BLCATGCT | |
Reference showing the relevant tissue of TIPIN | ||
Description by TissGene annotations | TissgsLTS |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
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GO ID | GO term | PubMed ID |
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TissGeneExp for TIPIN |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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![]() (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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![]() (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
BLCA | 0.248235191 | -0.822691124 | 1.070926316 | 1.07E-07 | 6.26E-06 |
LUSC | 0.297991125 | -0.968906914 | 1.266898039 | 5.53E-17 | 4.40E-16 |
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TissGene-miRNA for TIPIN |
![]() (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for TIPIN |
TissGeneSNV for TIPIN |
![]() Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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![]() (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.R142L | READ | 1 |
p.N270D | COAD | 1 |
p.D261H | BRCA | 1 |
p.E198K | PAAD | 1 |
p.E212K | UCEC | 1 |
p.K117N | UCEC | 1 |
p.G254R | SKCM | 1 |
p.A216T | UCEC | 1 |
p.E241K | BLCA | 1 |
p.P56S | SKCM | 1 |
p.A269T | STAD | 1 |
p.E160* | UCEC | 1 |
p.R142Q | THYM | 1 |
p.R58K | SKCM | 1 |
p.Q5* | HNSC | 1 |
p.P27T | THYM | 1 |
p.D168H | BLCA | 1 |
p.R144* | UCEC | 1 |
p.V60A | BRCA | 1 |
p.A162V | THCA | 1 |
p.V84I | UCEC | 1 |
p.I104M | LUAD | 1 |
p.M107I | OV | 1 |
p.D146H | KIRC | 1 |
p.F154C | UCEC | 1 |
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TissGeneCNV for TIPIN |
![]() (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for TIPIN |
![]() (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for TIPIN |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for TIPIN |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for TIPIN |
TissGeneDrug for TIPIN |
![]() (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for TIPIN |
![]() (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0851578 | Sleep Disorders | 1 | GAD |