TissGeneSummary for TEX13A |
Gene summary |
Basic gene information | Gene symbol | TEX13A |
Gene name | testis expressed 13A | |
Synonyms | - | |
Cytomap | UCSC genome browser: Xq22.3 | |
Type of gene | protein-coding | |
RefGenes | NM_001291277.1, NM_031274.4, | |
Description | testis-expressed sequence 13A protein | |
Modification date | 20141207 | |
dbXrefs | MIM : 300312 | |
HGNC : HGNC | ||
Ensembl : ENSG00000268629 | ||
HPRD : 02257 | ||
Vega : OTTHUMG00000022133 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_TEX13A | |
BioGPS: 56157 | ||
Pathway | NCI Pathway Interaction Database: TEX13A | |
KEGG: TEX13A | ||
REACTOME: TEX13A | ||
Pathway Commons: TEX13A | ||
Context | iHOP: TEX13A | |
ligand binding site mutation search in PubMed: TEX13A | ||
UCL Cancer Institute: TEX13A | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of TEX13A | ||
Description by TissGene annotations | TissgsKTS CNV lost TissGeneKTS |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for TEX13A |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for TEX13A |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for TEX13A |
TissGeneSNV for TEX13A |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.T120M | OV | 1 |
p.E352K | SKCM | 1 |
p.S257R | KIRC | 1 |
p.E119K | SKCM | 1 |
p.G158E | SARC | 1 |
p.R330S | LUAD | 1 |
p.R77H | OV | 1 |
p.G11W | ACC | 1 |
p.P259T | HNSC | 1 |
p.S309F | SKCM | 1 |
p.R370I | LUAD | 1 |
p.P349H | HNSC | 1 |
p.R240K | CESC | 1 |
p.L331F | ACC | 1 |
p.R198K | PAAD | 1 |
p.R393S | KIRC | 1 |
p.E255K | SKCM | 1 |
p.G158R | SKCM | 1 |
p.T316N | PAAD | 1 |
p.R393T | LUAD | 1 |
p.D394Y | BLCA | 1 |
p.E255K | STAD | 1 |
p.E33K | SKCM | 1 |
p.W69* | SKCM | 1 |
p.Q140P | BRCA | 1 |
p.E142K | SKCM | 1 |
p.A26S | HNSC | 1 |
p.R351K | SKCM | 1 |
p.G11R | LGG | 1 |
p.S42Y | LUAD | 1 |
p.S42F | SKCM | 1 |
p.P226S | SKCM | 1 |
p.R89M | UCEC | 1 |
p.Q262X | LIHC | 1 |
p.A180V | UCEC | 1 |
p.T258N | HNSC | 1 |
p.W222C | LUAD | 1 |
p.S102L | SKCM | 1 |
p.I317V | UCEC | 1 |
p.L308P | LUAD | 1 |
p.F293L | LUAD | 1 |
p.P310L | SKCM | 1 |
p.P350T | HNSC | 1 |
p.N38K | HNSC | 1 |
p.D144E | LUSC | 1 |
p.S391L | SARC | 1 |
p.G95C | LUAD | 1 |
p.P297S | SKCM | 1 |
p.S61N | HNSC | 1 |
p.Q313H | LUAD | 1 |
p.E196K | PRAD | 1 |
p.V17A | LUAD | 1 |
p.D340A | UCEC | 1 |
p.P310S | SKCM | 1 |
p.D266N | HNSC | 1 |
p.E215X | PRAD | 1 |
p.A97V | LUSC | 1 |
p.A233S | ACC | 1 |
p.L233M | LUAD | 1 |
p.L162M | PAAD | 1 |
p.E176K | SKCM | 1 |
p.L317I | PAAD | 1 |
p.V228M | COAD | 1 |
p.L249F | BRCA | 1 |
p.L334I | LUAD | 1 |
p.G189* | LUSC | 1 |
p.Y257D | KIRC | 1 |
p.P329Q | LUAD | 1 |
p.T68I | HNSC | 1 |
p.R91G | LUSC | 1 |
p.Q118K | LUSC | 1 |
p.S391P | SKCM | 1 |
p.E121D | UCEC | 1 |
p.E290K | SKCM | 1 |
p.S269L | PAAD | 1 |
p.R282Q | SKCM | 1 |
p.A180G | HNSC | 1 |
p.E37D | BLCA | 1 |
p.Q368* | HNSC | 1 |
p.E196Q | OV | 1 |
p.R89M | PAAD | 1 |
p.V200L | PAAD | 1 |
p.T236R | LUSC | 1 |
p.S289* | LUAD | 1 |
p.A52V | SKCM | 1 |
p.G156E | SKCM | 1 |
p.P8R | LUAD | 1 |
p.E33K | STAD | 1 |
p.E215* | PRAD | 1 |
p.S71G | ESCA | 1 |
p.D110E | LUSC | 1 |
p.D379N | HNSC | 1 |
p.P335L | UVM | 1 |
p.P320S | ESCA | 1 |
p.M347I | LUAD | 1 |
p.G190E | SKCM | 1 |
p.A173V | DLBC | 1 |
p.L36F | READ | 1 |
p.A97T | OV | 1 |
p.A66D | LUSC | 1 |
p.C344Y | TGCT | 1 |
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TissGeneCNV for TEX13A |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for TEX13A |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for TEX13A |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for TEX13A |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for TEX13A |
TissGeneDrug for TEX13A |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for TEX13A |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |