TissGeneSummary for COL20A1 |
Gene summary |
Basic gene information | Gene symbol | COL20A1 |
Gene name | collagen, type XX, alpha 1 | |
Synonyms | bA261N11.4 | |
Cytomap | UCSC genome browser: 20q13.33 | |
Type of gene | protein-coding | |
RefGenes | NM_020882.2, | |
Description | collagen alpha-1(XX) chaincollagen-like protein | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000101203 | ||
HPRD : 17215 | ||
Vega : OTTHUMG00000032964 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_COL20A1 | |
BioGPS: 57642 | ||
Pathway | NCI Pathway Interaction Database: COL20A1 | |
KEGG: COL20A1 | ||
REACTOME: COL20A1 | ||
Pathway Commons: COL20A1 | ||
Context | iHOP: COL20A1 | |
ligand binding site mutation search in PubMed: COL20A1 | ||
UCL Cancer Institute: COL20A1 | ||
Assigned class in TissGDB* | B | |
Included tissue-specific gene expression resources | ||
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | BrainTestis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | GBM,LGGTGCT | |
Reference showing the relevant tissue of COL20A1 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
Top |
TissGeneExp for COL20A1 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
Top |
TissGene-miRNA for COL20A1 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
Top |
TissGeneMut for COL20A1 |
TissGeneSNV for COL20A1 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.G464A | LUAD | 2 |
p.G261E | SKCM | 2 |
p.G254E | SKCM | 2 |
p.D1116N | SKCM | 1 |
p.E68K | SKCM | 1 |
p.E114* | LIHC | 1 |
p.V1173M | STAD | 1 |
p.D161N | SKCM | 1 |
p.S1072F | SKCM | 1 |
p.S511F | SKCM | 1 |
p.P1232L | SKCM | 1 |
p.S125R | SARC | 1 |
p.F875S | LUSC | 1 |
p.E1213Q | BLCA | 1 |
p.E917* | LUAD | 1 |
p.R1254H | UCS | 1 |
p.R171K | SKCM | 1 |
p.V902I | STAD | 1 |
p.P705L | SKCM | 1 |
p.T644A | UCEC | 1 |
p.G460V | BLCA | 1 |
p.L15Q | KIRC | 1 |
p.R842L | SARC | 1 |
p.P588L | SKCM | 1 |
p.A300S | THYM | 1 |
p.G798V | LUAD | 1 |
p.S599L | CESC | 1 |
p.V1008I | UCEC | 1 |
p.V291M | SKCM | 1 |
p.S200I | SKCM | 1 |
p.L116Q | LUAD | 1 |
p.E240K | STAD | 1 |
p.R1167* | PAAD | 1 |
p.E114X | LIHC | 1 |
p.P892L | HNSC | 1 |
p.E50K | SKCM | 1 |
p.A848T | THCA | 1 |
p.G142R | SKCM | 1 |
p.P904Q | LUAD | 1 |
p.V710A | SKCM | 1 |
p.W487C | THYM | 1 |
p.R709T | LUSC | 1 |
p.K689N | UCEC | 1 |
p.V909I | STAD | 1 |
p.V1061L | SKCM | 1 |
p.Y741S | SKCM | 1 |
p.P712L | SKCM | 1 |
p.G30S | COAD | 1 |
p.E914D | COAD | 1 |
p.H777Y | SKCM | 1 |
p.E247K | STAD | 1 |
p.A281S | LUAD | 1 |
p.Y678C | KIRP | 1 |
p.P777L | SKCM | 1 |
p.Q828H | LIHC | 1 |
p.R1137K | SKCM | 1 |
p.R740C | SKCM | 1 |
p.T876M | UCEC | 1 |
p.V446M | STAD | 1 |
p.W1263* | LUAD | 1 |
p.S1074F | SKCM | 1 |
p.E924K | CESC | 1 |
p.S1023L | ESCA | 1 |
p.R1174* | PAAD | 1 |
p.E1147D | LUAD | 1 |
p.D192N | SKCM | 1 |
p.V746M | SKCM | 1 |
p.S643C | LUAD | 1 |
p.A477T | READ | 1 |
p.E1147Q | HNSC | 1 |
p.T298I | KIRP | 1 |
p.T620S | CESC | 1 |
p.V703I | UCEC | 1 |
p.V58E | LUAD | 1 |
p.S1030L | ESCA | 1 |
p.S636C | LUAD | 1 |
p.R171C | SKCM | 1 |
p.G1112E | SKCM | 1 |
p.D837Y | THYM | 1 |
p.H1110N | LUAD | 1 |
p.R171T | LIHC | 1 |
p.H1117N | LUAD | 1 |
p.Q1116K | COAD | 1 |
p.P666S | ACC | 1 |
p.P1177T | PAAD | 1 |
p.S403F | SKCM | 1 |
p.P555T | HNSC | 1 |
p.R551C | STAD | 1 |
p.P1230L | DLBC | 1 |
p.R1241H | UCS | 1 |
p.G174S | ACC | 1 |
p.V649L | ESCA | 1 |
p.G1124D | UCEC | 1 |
p.Q203H | LUAD | 1 |
p.S49L | SKCM | 1 |
p.V703A | SKCM | 1 |
p.P764L | STAD | 1 |
p.R867W | SKCM | 1 |
p.P866L | UCEC | 1 |
p.G55S | PRAD | 1 |
p.G1286E | SKCM | 1 |
p.G259D | STAD | 1 |
p.P1158S | SKCM | 1 |
p.A864S | SARC | 1 |
p.R1144K | SKCM | 1 |
p.G53S | PAAD | 1 |
p.V1068L | SKCM | 1 |
p.G1148E | SKCM | 1 |
p.E1140D | LUAD | 1 |
p.G1105E | SKCM | 1 |
p.P712S | SKCM | 1 |
p.H403Y | STAD | 1 |
p.P899L | HNSC | 1 |
p.S820G | KIRC | 1 |
p.G1105E | STAD | 1 |
p.G514D | LUAD | 1 |
p.W1250* | LUAD | 1 |
p.G22V | KICH | 1 |
p.A930D | LUAD | 1 |
p.R108Q | UCEC | 1 |
p.P1260L | SKCM | 1 |
p.A855T | THCA | 1 |
p.R625H | THYM | 1 |
p.P784L | SKCM | 1 |
p.R585S | LUSC | 1 |
p.G457A | LUAD | 1 |
p.R471L | LUSC | 1 |
p.Q544H | LUAD | 1 |
p.R582K | GBM | 1 |
p.P790L | STAD | 1 |
p.N1216S | STAD | 1 |
p.E968K | SKCM | 1 |
p.S29I | SARC | 1 |
p.R518W | STAD | 1 |
p.L877F | LIHC | 1 |
p.G1157S | ACC | 1 |
p.A207T | STAD | 1 |
p.T1016M | LUAD | 1 |
p.A472V | GBM | 1 |
p.G870C | ESCA | 1 |
p.S398F | SKCM | 1 |
p.G261R | SKCM | 1 |
p.E791K | SKCM | 1 |
p.G1231S | COAD | 1 |
p.T288M | LUSC | 1 |
p.A155V | SKCM | 1 |
p.A572S | STAD | 1 |
p.Q1122L | LUSC | 1 |
p.G877C | ESCA | 1 |
p.R178C | SKCM | 1 |
p.R1265H | SKCM | 1 |
p.P1233L | LGG | 1 |
p.R108W | STAD | 1 |
p.P995L | LIHC | 1 |
p.R726H | STAD | 1 |
p.G931R | CESC | 1 |
p.P1232T | LUAD | 1 |
p.E784K | SKCM | 1 |
p.Q94H | UCEC | 1 |
p.D145Y | LUAD | 1 |
p.M1269T | DLBC | 1 |
p.W404* | SKCM | 1 |
p.S193I | SKCM | 1 |
p.G613E | SKCM | 1 |
p.C1057F | COAD | 1 |
p.R1167X | COAD | 1 |
p.G433R | SKCM | 1 |
p.G791V | LUAD | 1 |
p.T288M | BRCA | 1 |
p.P128T | STAD | 1 |
p.G232R | SKCM | 1 |
p.E910* | LUAD | 1 |
p.S888I | UCEC | 1 |
p.S52I | SARC | 1 |
p.R1134K | SKCM | 1 |
p.K792* | SKCM | 1 |
p.P1170T | PAAD | 1 |
p.Q25H | CHOL | 1 |
p.R913G | LUAD | 1 |
p.A274S | LUAD | 1 |
p.R1252H | SKCM | 1 |
Top |
TissGeneCNV for COL20A1 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
Top |
TissGeneFusions for COL20A1 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Top |
TissGeneNet for COL20A1 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
Top |
TissGeneProg for COL20A1 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Top |
TissGeneClin for COL20A1 |
TissGeneDrug for COL20A1 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
TissGeneDisease for COL20A1 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0006142 | Malignant neoplasm of breast | 1 | BeFree |
umls:C0678222 | Breast Carcinoma | 1 | BeFree |