TissGeneSummary for CATSPERG |
Gene summary |
Basic gene information | Gene symbol | CATSPERG |
Gene name | catsper channel auxiliary subunit gamma | |
Synonyms | C19orf15 | |
Cytomap | UCSC genome browser: 19q13.1 | |
Type of gene | protein-coding | |
RefGenes | NM_021185.4, | |
Description | cation channel sperm-associated protein subunit gamma | |
Modification date | 20141207 | |
dbXrefs | MIM : 613452 | |
HGNC : HGNC | ||
Ensembl : ENSG00000099338 | ||
HPRD : 12698 | ||
Vega : OTTHUMG00000153223 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_CATSPERG | |
BioGPS: 57828 | ||
Pathway | NCI Pathway Interaction Database: CATSPERG | |
KEGG: CATSPERG | ||
REACTOME: CATSPERG | ||
Pathway Commons: CATSPERG | ||
Context | iHOP: CATSPERG | |
ligand binding site mutation search in PubMed: CATSPERG | ||
UCL Cancer Institute: CATSPERG | ||
Assigned class in TissGDB* | B | |
Included tissue-specific gene expression resources | HPA,TiGER,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of CATSPERG | ||
Description by TissGene annotations | Fused withOncogene Fused withTSGene |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for CATSPERG |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
COAD | -2.124811282 | -0.88680359 | -1.238007692 | 2.20E-05 | 9.25E-05 |
LUSC | -1.695802911 | -0.327297029 | -1.368505882 | 3.65E-09 | 1.19E-08 |
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TissGene-miRNA for CATSPERG |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for CATSPERG |
TissGeneSNV for CATSPERG |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.H1001Y | SKCM | 2 |
p.E967K | SKCM | 2 |
p.L948M | UCEC | 1 |
p.S493Y | UCEC | 1 |
p.R1102W | BRCA | 1 |
p.S647N | PAAD | 1 |
p.Q381* | HNSC | 1 |
p.Q943E | LUSC | 1 |
p.A1014T | UCEC | 1 |
p.W556* | LUSC | 1 |
p.Q597E | STAD | 1 |
p.G1135D | STAD | 1 |
p.A302T | ESCA | 1 |
p.G734A | UCEC | 1 |
p.S1139N | HNSC | 1 |
p.E503K | SKCM | 1 |
p.H1001L | SKCM | 1 |
p.I491V | LUAD | 1 |
p.P1063H | UCEC | 1 |
p.P388L | SKCM | 1 |
p.D830V | LIHC | 1 |
p.T936I | UCEC | 1 |
p.R212Q | DLBC | 1 |
p.E395* | LUSC | 1 |
p.W983L | TGCT | 1 |
p.G1122R | BLCA | 1 |
p.A802V | BRCA | 1 |
p.F779L | LUSC | 1 |
p.S496F | SKCM | 1 |
p.S1128F | OV | 1 |
p.E358Q | BLCA | 1 |
p.P868L | SKCM | 1 |
p.E444* | UCEC | 1 |
p.E749Q | BLCA | 1 |
p.W983X | SKCM | 1 |
p.F759L | KIRC | 1 |
p.E1002K | LUAD | 1 |
p.K1096M | UCEC | 1 |
p.T827M | THYM | 1 |
p.S1075T | STAD | 1 |
p.N1047K | LUSC | 1 |
p.E967K | PAAD | 1 |
p.L920V | CESC | 1 |
p.L29P | ACC | 1 |
p.V667G | PRAD | 1 |
p.I517M | LUAD | 1 |
p.P1063L | UCEC | 1 |
p.Y371F | LUAD | 1 |
p.L465I | STAD | 1 |
p.D993Y | UCEC | 1 |
p.S1140F | SKCM | 1 |
p.W983* | SKCM | 1 |
p.S523L | SKCM | 1 |
p.E814D | STAD | 1 |
p.S59G | LIHC | 1 |
p.Y696H | UCEC | 1 |
p.R138C | SARC | 1 |
p.A295T | COAD | 1 |
p.L816M | THCA | 1 |
p.G867V | LUAD | 1 |
p.M1134I | ESCA | 1 |
p.E609K | BLCA | 1 |
p.L612V | BLCA | 1 |
p.Y621H | STAD | 1 |
p.L1009F | SKCM | 1 |
p.A529T | UCEC | 1 |
p.A1152V | SKCM | 1 |
p.A1026V | PRAD | 1 |
p.G952V | LUAD | 1 |
p.P927H | PRAD | 1 |
p.S641W | LUAD | 1 |
p.E1151K | SKCM | 1 |
p.P1027S | SKCM | 1 |
p.R625Q | GBM | 1 |
p.V558G | BRCA | 1 |
p.P804S | THYM | 1 |
p.I491M | BLCA | 1 |
p.S980N | SKCM | 1 |
p.P1063L | SKCM | 1 |
p.R210G | LIHC | 1 |
p.V602I | ACC | 1 |
p.R457P | LUAD | 1 |
p.Y906D | UCEC | 1 |
p.Y485H | HNSC | 1 |
p.I449M | SKCM | 1 |
p.E808* | BLCA | 1 |
p.T1099M | READ | 1 |
p.G776R | KIRC | 1 |
p.D1145E | LUAD | 1 |
p.M1134L | BLCA | 1 |
p.T827M | CESC | 1 |
p.L725F | LUAD | 1 |
p.A1110T | LGG | 1 |
p.E514K | SKCM | 1 |
p.K269N | ESCA | 1 |
p.R337C | SKCM | 1 |
p.R989W | UCEC | 1 |
p.L508R | STAD | 1 |
p.S840I | THYM | 1 |
p.Y746C | LUAD | 1 |
p.V434A | BLCA | 1 |
p.W1103* | SKCM | 1 |
p.R900S | LUAD | 1 |
p.K345N | BLCA | 1 |
p.V950M | HNSC | 1 |
p.T243I | THYM | 1 |
p.S840I | UCEC | 1 |
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TissGeneCNV for CATSPERG |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for CATSPERG |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | FusionScan | BRCA | TCGA-D8-A1XZ-01A | PAK4-CATSPERG | 5'UTR-CDS | chr19:39616559 | chr19:38848917 |
Chimerdb3.0 | FusionScan | BRCA | TCGA-D8-A1XZ-01A | PAK4-CATSPERG | 5'UTR-CDS | chr19:39616559 | chr19:38851128 |
Chimerdb3.0 | FusionScan | BRCA | TCGA-D8-A1XZ-01A | PAK4-CATSPERG | 5'UTR-CDS | chr19:39616559 | chr19:38860798 |
Chimerdb3.0 | FusionScan | MESO | TCGA-SH-A7BD-01A | CATSPERG-RASSF1 | In-Frame | chr19:38828144 | chr3:50369585 |
TCGAfusionPortal | PRADA | BRCA | TCGA-D8-A1XZ-01A | PAK4-CATSPERG | 5UTR-CDS | Chr19:39616559 | Chr19:38848918 |
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TissGeneNet for CATSPERG |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for CATSPERG |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for CATSPERG |
TissGeneDrug for CATSPERG |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for CATSPERG |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |