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| TissGeneSummary for REG1A |
 Gene summary |
| Basic gene information | Gene symbol | REG1A |
| Gene name | regenerating islet-derived 1 alpha | |
| Synonyms | ICRF|P19|PSP|PSPS|PSPS1|PTP|REG | |
| Cytomap | UCSC genome browser: 2p12 | |
| Type of gene | protein-coding | |
| RefGenes | NM_002909.4, | |
| Description | REG-1-alphaislet cells regeneration factorislet of langerhans regenerating proteinlithostathine 1 alphalithostathine-1-alphapancreatic stone protein, secretorypancreatic thread proteinprotein-Xregenerating islet-derived protein 1-alpharegeneratin | |
| Modification date | 20141207 | |
| dbXrefs | MIM : 167770 | |
| HGNC : HGNC | ||
| Ensembl : ENSG00000115386 | ||
| HPRD : 01338 | ||
| Vega : OTTHUMG00000130016 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_REG1A | |
| BioGPS: 5967 | ||
| Pathway | NCI Pathway Interaction Database: REG1A | |
| KEGG: REG1A | ||
| REACTOME: REG1A | ||
| Pathway Commons: REG1A | ||
| Context | iHOP: REG1A | |
| ligand binding site mutation search in PubMed: REG1A | ||
| UCL Cancer Institute: REG1A | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | TiGER,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Pancreas | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | PAAD | |
| Reference showing the relevant tissue of REG1A | ||
| Description by TissGene annotations | ||
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
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| TissGeneExp for REG1A |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
 |
| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| KIRC | 6.117239932 | 2.204174654 | 3.913065278 | 7.67E-11 | 2.76E-10 |
| LUSC | -0.696589725 | -1.916656391 | 1.220066667 | 8.57E-06 | 1.96E-05 |
| LUAD | -0.500429177 | -1.852806763 | 1.352377586 | 0.00136 | 0.002913543 |
| COAD | 7.190072945 | 2.792646022 | 4.397426923 | 0.000904 | 0.002613013 |
| KICH | -1.888694901 | 0.731125099 | -2.61982 | 0.000281 | 0.000679829 |
| LIHC | 1.148469099 | -1.478128901 | 2.626598 | 0.000117 | 0.000397335 |
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| TissGene-miRNA for REG1A |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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| TissGeneMut for REG1A |
| TissGeneSNV for REG1A |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.W113* | SKCM | 2 |
| p.W113X | SKCM | 2 |
| p.R109H | CESC | 1 |
| p.R33L | LUAD | 1 |
| p.G39D | LUAD | 1 |
| p.S123F | SKCM | 1 |
| p.S142L | LUSC | 1 |
| p.T93P | LUSC | 1 |
| p.R109H | STAD | 1 |
| p.R54C | UCEC | 1 |
| p.R110H | COAD | 1 |
| p.W57* | SKCM | 1 |
| p.Q147K | HNSC | 1 |
| p.R54S | LUAD | 1 |
| p.H112Y | HNSC | 1 |
| p.K89T | STAD | 1 |
| p.W149* | SKCM | 1 |
| p.P37L | LGG | 1 |
| p.W111* | ESCA | 1 |
| p.D151Y | LUAD | 1 |
| p.G39S | LUSC | 1 |
| p.Y7* | LUAD | 1 |
| p.G101V | LUSC | 1 |
| p.K107T | BRCA | 1 |
| p.F158L | UCEC | 1 |
| p.F83I | HNSC | 1 |
| p.S159Y | LUAD | 1 |
| p.D156N | SKCM | 1 |
| p.W124C | LUAD | 1 |
| p.N133D | COAD | 1 |
| p.W149X | SKCM | 1 |
| p.E80D | HNSC | 1 |
| p.M67I | HNSC | 1 |
| p.R110H | READ | 1 |
| p.W111X | ESCA | 1 |
| p.D104N | BLCA | 1 |
| p.V161L | LUSC | 1 |
| p.R54C | PRAD | 1 |
| p.N66K | LUAD | 1 |
| p.R110H | UCEC | 1 |
| p.C137F | LUSC | 1 |
| p.A42D | UCEC | 1 |
| p.R110H | BLCA | 1 |
| p.H103Y | BLCA | 1 |
| p.R54C | THCA | 1 |
| p.K107N | HNSC | 1 |
| p.Q31H | LUAD | 1 |
| p.E55K | CESC | 1 |
| p.S131N | LUAD | 1 |
| p.80_81EG>DC | HNSC | 1 |
| p.R110L | HNSC | 1 |
| p.S117F | SKCM | 1 |
| p.V58I | SKCM | 1 |
| p.G81R | SKCM | 1 |
| p.S131I | LUAD | 1 |
| p.S69L | SKCM | 1 |
| p.A128V | BLCA | 1 |
| p.P105H | HNSC | 1 |
| p.E155K | LUSC | 1 |
| p.C137F | LUAD | 1 |
| p.R44H | STAD | 1 |
| p.T93S | HNSC | 1 |
| p.S20R | LUAD | 1 |
| p.M67I | SKCM | 1 |
| p.R110C | THYM | 1 |
| p.H112R | LIHC | 1 |
| p.K163N | LUAD | 1 |
| p.C47F | HNSC | 1 |
| p.C137Y | BLCA | 1 |
| p.G81C | LUAD | 1 |
| p.P37A | LUSC | 1 |
| p.A85P | LUSC | 1 |
| p.P105Q | HNSC | 1 |
| p.Q21K | HNSC | 1 |
| p.R110C | UCEC | 1 |
| p.R33G | LUSC | 1 |
| p.Q26K | LUAD | 1 |
| p.W57X | SKCM | 1 |
| p.E80K | LUSC | 1 |
| p.A2S | BLCA | 1 |
| p.Q3K | LUAD | 1 |
| p.E52K | SKCM | 1 |
| p.D151G | COAD | 1 |
| p.S45F | BLCA | 1 |
| p.M15I | BLCA | 1 |
| p.G81C | HNSC | 1 |
| p.S91I | LUAD | 1 |
| p.Q31H | HNSC | 1 |
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| TissGeneCNV for REG1A |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| TissGeneFusions for REG1A |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| Chimerdb3.0 | ChiTaRs | NA | CK818890 | REG1A-GNA11 | chr2:79350531 | chr19:3115035 | |
| Chimerdb3.0 | ChiTaRs | NA | BM126025 | REG1A-GNA11 | chr2:79350535 | chr19:3118933 | |
| Chimerdb3.0 | ChiTaRs | NA | CA842583 | REG1A-REG1A | chr2:79350529 | chr2:79350465 | |
| Chimerdb3.0 | ChiTaRs | NA | CK818891 | GNA11-REG1A | chr19:3119254 | chr2:79350483 |
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| TissGeneNet for REG1A |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| BRCA (tumor) | BRCA (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| COAD (tumor) | COAD (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| HNSC (tumor) | HNSC (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| KICH (tumor) | KICH (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| KIRC (tumor) | KIRC (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| KIRP (tumor) | KIRP (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| LIHC (tumor) | LIHC (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| LUAD (tumor) | LUAD (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| LUSC (tumor) | LUSC (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| PRAD (tumor) | PRAD (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| STAD (tumor) | STAD (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
 |  |
| THCA (tumor) | THCA (normal) |
| REG1A, VAV2, HNF4A, STAT3, REG3A (tumor) | REG1A, VAV2, HNF4A, STAT3, REG3A (normal) |
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| TissGeneProg for REG1A |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| TissGeneClin for REG1A |
| TissGeneDrug for REG1A |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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| TissGeneDisease for REG1A |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0206659 | Embryonal Carcinoma | 26 | BeFree |
| umls:C0596263 | Carcinogenesis | 12 | BeFree |
| umls:C0023493 | Adult T-Cell Lymphoma/Leukemia | 8 | BeFree |
| umls:C0009402 | Colorectal Carcinoma | 7 | BeFree |
| umls:C0011854 | Diabetes Mellitus, Insulin-Dependent | 7 | BeFree,LHGDN |
| umls:C0006142 | Malignant neoplasm of breast | 6 | BeFree |
| umls:C0038356 | Stomach Neoplasms | 5 | CTD_mouse,LHGDN |
| umls:C0678222 | Breast Carcinoma | 5 | BeFree |
| umls:C1527249 | Colorectal Cancer | 5 | BeFree |
| umls:C2239176 | Liver carcinoma | 5 | BeFree |
| umls:C0001418 | Adenocarcinoma | 4 | BeFree,LHGDN |
| umls:C0011849 | Diabetes Mellitus | 4 | BeFree |
| umls:C0021390 | Inflammatory Bowel Diseases | 4 | BeFree |
| umls:C0025202 | melanoma | 4 | BeFree |
| umls:C0699791 | Stomach Carcinoma | 4 | BeFree |
| umls:C0949664 | Tauopathies | 4 | BeFree |
| umls:C0002395 | Alzheimer's Disease | 3 | BeFree |
| umls:C0003873 | Rheumatoid Arthritis | 3 | BeFree |
| umls:C0009404 | Colorectal Neoplasms | 3 | BeFree,LHGDN |
| umls:C0011847 | Diabetes | 3 | BeFree |
| umls:C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 3 | BeFree,GAD |
| umls:C0019163 | Hepatitis B | 3 | BeFree |
| umls:C0023418 | leukemia | 3 | BeFree |
| umls:C0024623 | Malignant neoplasm of stomach | 3 | BeFree |
| umls:C0027627 | Neoplasm Metastasis | 3 | BeFree |
| umls:C0029925 | Ovarian Carcinoma | 3 | BeFree |
| umls:C0030305 | Pancreatitis | 3 | BeFree,GAD |
| umls:C0038868 | Progressive supranuclear palsy | 3 | BeFree |
| umls:C0149521 | Pancreatitis, Chronic | 3 | BeFree,RGD |
| umls:C0206664 | Teratocarcinoma | 3 | BeFree |
| umls:C0376358 | Malignant neoplasm of prostate | 3 | BeFree |
| umls:C0600139 | Prostate carcinoma | 3 | BeFree |
| umls:C0684249 | Carcinoma of lung | 3 | BeFree |
| umls:C1140680 | Malignant neoplasm of ovary | 3 | BeFree |
| umls:C0001430 | Adenoma | 2 | BeFree |
| umls:C0002736 | Amyotrophic Lateral Sclerosis | 2 | BeFree |
| umls:C0004364 | Autoimmune Diseases | 2 | BeFree |
| umls:C0007134 | Renal Cell Carcinoma | 2 | BeFree |
| umls:C0007570 | Celiac Disease | 2 | BeFree |
| umls:C0010346 | Crohn Disease | 2 | BeFree |
| umls:C0011853 | Diabetes Mellitus, Experimental | 2 | RGD |
| umls:C0014859 | Esophageal Neoplasms | 2 | BeFree,LHGDN |
| umls:C0017638 | Glioma | 2 | BeFree |
| umls:C0019693 | HIV Infections | 2 | BeFree |
| umls:C0023492 | Leukemia, T-Cell | 2 | BeFree |
| umls:C0026769 | Multiple Sclerosis | 2 | BeFree |
| umls:C0028326 | Noonan Syndrome | 2 | BeFree |
| umls:C0028754 | Obesity | 2 | BeFree |
| umls:C0029408 | Degenerative polyarthritis | 2 | BeFree |
| umls:C0031511 | Pheochromocytoma | 2 | BeFree |
| umls:C0033860 | Psoriasis | 2 | BeFree |
| umls:C0034345 | Pyruvate Dehydrogenase Complex Deficiency Disease | 2 | BeFree |
| umls:C0034885 | Rectal Neoplasms | 2 | BeFree |
| umls:C0149925 | Small cell carcinoma of lung | 2 | BeFree |
| umls:C0175704 | LEOPARD Syndrome | 2 | BeFree |
| umls:C0242379 | Malignant neoplasm of lung | 2 | BeFree |
| umls:C1527408 | Rectal Tumors | 2 | BeFree |
| umls:C0002793 | Anaplasia | 1 | BeFree |
| umls:C0004114 | Astrocytoma | 1 | BeFree |
| umls:C0004763 | Barrett Esophagus | 1 | LHGDN |
| umls:C0004943 | Behcet Syndrome | 1 | BeFree |
| umls:C0006663 | Calcinosis | 1 | GAD |
| umls:C0007131 | Non-Small Cell Lung Carcinoma | 1 | BeFree |
| umls:C0008312 | Primary biliary cirrhosis | 1 | BeFree |
| umls:C0008340 | Choledochal Cyst | 1 | LHGDN |
| umls:C0009324 | Ulcerative Colitis | 1 | BeFree |
| umls:C0009375 | Colonic Neoplasms | 1 | RGD |
| umls:C0010674 | Cystic Fibrosis | 1 | BeFree |
| umls:C0013336 | Dwarfism | 1 | BeFree |
| umls:C0014072 | Experimental Autoimmune Encephalomyelitis | 1 | BeFree |
| umls:C0014743 | Erythema Nodosum | 1 | BeFree |
| umls:C0019158 | Hepatitis | 1 | BeFree |
| umls:C0019159 | Hepatitis A | 1 | BeFree |
| umls:C0020456 | Hyperglycemia | 1 | BeFree |
| umls:C0020538 | Hypertensive disease | 1 | BeFree |
| umls:C0023470 | Myeloid Leukemia | 1 | BeFree |
| umls:C0023487 | Acute Promyelocytic Leukemia | 1 | BeFree |
| umls:C0023903 | Liver neoplasms | 1 | BeFree |
| umls:C0024121 | Lung Neoplasms | 1 | BeFree |
| umls:C0026269 | Mitral Valve Stenosis | 1 | BeFree |
| umls:C0027051 | Myocardial Infarction | 1 | RGD |
| umls:C0027430 | Nasal Polyps | 1 | BeFree |
| umls:C0027819 | Neuroblastoma | 1 | BeFree |
| umls:C0029463 | Osteosarcoma | 1 | BeFree |
| umls:C0030293 | Pancreatic Insufficiency | 1 | BeFree |
| umls:C0032000 | Pituitary Adenoma | 1 | BeFree |
| umls:C0032002 | Pituitary Diseases | 1 | BeFree |
| umls:C0032463 | Polycythemia Vera | 1 | BeFree |
| umls:C0035335 | Retinoblastoma | 1 | BeFree |
| umls:C0040336 | Tobacco Use Disorder | 1 | GAD |
| umls:C0042769 | Virus Diseases | 1 | BeFree |
| umls:C0079773 | Lymphoma, T-Cell, Cutaneous | 1 | BeFree |
| umls:C0085669 | Acute leukemia | 1 | BeFree |
| umls:C0086981 | Sicca Syndrome | 1 | BeFree |
| umls:C0152018 | Esophageal carcinoma | 1 | BeFree |
| umls:C0206093 | Neuroectodermal Tumors | 1 | BeFree |
| umls:C0206624 | Hepatoblastoma | 1 | BeFree |
| umls:C0206696 | Carcinoma, Signet Ring Cell | 1 | BeFree |
| umls:C0206716 | Ganglioglioma | 1 | BeFree |
| umls:C0233715 | Speech impairment | 1 | BeFree |
| umls:C0235782 | Gallbladder Carcinoma | 1 | BeFree |
| umls:C0263361 | Psoriasis vulgaris | 1 | BeFree |
| umls:C0266999 | Vesicular Stomatitis | 1 | BeFree |
| umls:C0267963 | Exocrine pancreatic insufficiency | 1 | BeFree |
| umls:C0271642 | Fibrocalculous pancreatic diabetes | 1 | BeFree |
| umls:C0278498 | Malignant neoplasm of stomach stage IV | 1 | BeFree |
| umls:C0278701 | Gastric Adenocarcinoma | 1 | BeFree |
| umls:C0338656 | Impaired cognition | 1 | BeFree |
| umls:C0349639 | Juvenile Myelomonocytic Leukemia | 1 | BeFree |
| umls:C0375019 | Human T-cell lymphotrophic virus, type I [HTLV-I] | 1 | BeFree |
| umls:C0375021 | Human immunodeficiency virus, type 2 [HIV-2] infection in conditions classified elsewhere and of unspecified site | 1 | BeFree |
| umls:C0376532 | Epilepsy, Rolandic | 1 | BeFree |
| umls:C0521158 | Recurrent tumor | 1 | BeFree |
| umls:C0524620 | Metabolic Syndrome X | 1 | RGD |
| umls:C0524851 | Neurodegenerative Disorders | 1 | BeFree |
| umls:C0546837 | Malignant neoplasm of esophagus | 1 | BeFree |
| umls:C0585442 | Osteosarcoma of bone | 1 | BeFree |
| umls:C0587248 | Costello syndrome (disorder) | 1 | BeFree |
| umls:C0699885 | Carcinoma of bladder | 1 | BeFree |
| umls:C0700095 | Central neuroblastoma | 1 | BeFree |
| umls:C0740457 | Malignant neoplasm of kidney | 1 | BeFree |
| umls:C0744310 | gastritis h pylori | 1 | BeFree |
| umls:C0751072 | Frontotemporal Lobar Degeneration | 1 | BeFree |
| umls:C0850666 | Helicobacter pylori infection | 1 | BeFree |
| umls:C0877008 | Enzyme inhibition disorder | 1 | BeFree |
| umls:C1292769 | Precursor B-cell lymphoblastic leukemia | 1 | BeFree |
| umls:C1319315 | Adenocarcinoma of large intestine | 1 | BeFree |
| umls:C1321872 | Stage IV Skin Melanoma | 1 | BeFree |
| umls:C1335302 | Pancreatic Ductal Adenocarcinoma | 1 | BeFree |
| umls:C1336735 | Treatment related acute myeloid leukaemia | 1 | BeFree |
| umls:C1458155 | Mammary Neoplasms | 1 | LHGDN |
| umls:C1845668 | Perisylvian syndrome | 1 | BeFree |
| umls:C2931352 | Familial renal cell carcinoma | 1 | BeFree |
| umls:C3826457 | Diabetes in children | 1 | BeFree |
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