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TissGeneSummary for AGBL5 |
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Basic gene information | Gene symbol | AGBL5 |
Gene name | ATP/GTP binding protein-like 5 | |
Synonyms | CCP5 | |
Cytomap | UCSC genome browser: 2p23.3 | |
Type of gene | protein-coding | |
RefGenes | NM_001035507.2, NM_021831.5,NR_104246.1, | |
Description | ATP/GTP-binding protein-like 5cytosolic carboxypeptidase 5cytosolic carboxypeptidase-like protein 5 | |
Modification date | 20141207 | |
dbXrefs | MIM : 615900 | |
HGNC : HGNC | ||
Ensembl : ENSG00000084693 | ||
HPRD : 07968 | ||
Vega : OTTHUMG00000128406 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_AGBL5 | |
BioGPS: 60509 | ||
Pathway | NCI Pathway Interaction Database: AGBL5 | |
KEGG: AGBL5 | ||
REACTOME: AGBL5 | ||
Pathway Commons: AGBL5 | ||
Context | iHOP: AGBL5 | |
ligand binding site mutation search in PubMed: AGBL5 | ||
UCL Cancer Institute: AGBL5 | ||
Assigned class in TissGDB* | B | |
Included tissue-specific gene expression resources | HPA,TiGER,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | CervixTestis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | CESCTGCT | |
Reference showing the relevant tissue of AGBL5 | ||
Description by TissGene annotations | TissgsLTS Fused withTSGene |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
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GO ID | GO term | PubMed ID |
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TissGeneExp for AGBL5 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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![]() (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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![]() (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
KICH | -0.58698197 | 0.66989003 | -1.256872 | 8.59E-10 | 5.50E-09 |
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TissGene-miRNA for AGBL5 |
![]() (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for AGBL5 |
TissGeneSNV for AGBL5 |
![]() Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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![]() (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.R123* | SKCM | 1 |
p.S632Y | LIHC | 1 |
p.D206N | COAD | 1 |
p.A325T | SARC | 1 |
p.P665S | SKCM | 1 |
p.V874F | BLCA | 1 |
p.E33K | BLCA | 1 |
p.S99N | PRAD | 1 |
p.R783Q | ESCA | 1 |
p.R640Q | STAD | 1 |
p.T133M | STAD | 1 |
p.G446R | LIHC | 1 |
p.G508E | SKCM | 1 |
p.G36A | CESC | 1 |
p.D534N | BLCA | 1 |
p.E481Q | STAD | 1 |
p.R121C | PAAD | 1 |
p.S862I | UCEC | 1 |
p.Y461C | UCEC | 1 |
p.D473N | COAD | 1 |
p.L636F | STAD | 1 |
p.R640Q | BLCA | 1 |
p.Y513C | STAD | 1 |
p.Q708K | ACC | 1 |
p.P698H | UCEC | 1 |
p.P275S | HNSC | 1 |
p.W592* | CESC | 1 |
p.H141Y | LUSC | 1 |
p.P668A | LUAD | 1 |
p.R638W | PAAD | 1 |
p.D273N | CESC | 1 |
p.S348P | STAD | 1 |
p.L880M | STAD | 1 |
p.G215V | COAD | 1 |
p.R490T | HNSC | 1 |
p.G17R | BRCA | 1 |
p.R341H | LGG | 1 |
p.L586F | HNSC | 1 |
p.N859T | LGG | 1 |
p.F54L | READ | 1 |
p.S664F | OV | 1 |
p.L399F | UCEC | 1 |
p.Y161* | HNSC | 1 |
p.R223H | COAD | 1 |
p.R80Q | ESCA | 1 |
p.E414Q | CESC | 1 |
p.G441D | CESC | 1 |
p.E68K | CESC | 1 |
p.E870Q | CESC | 1 |
p.I92S | UCEC | 1 |
p.A240V | LGG | 1 |
p.L137I | STAD | 1 |
p.A39V | LGG | 1 |
p.R638W | BLCA | 1 |
p.P406L | SKCM | 1 |
p.R13H | COAD | 1 |
p.P421A | LUAD | 1 |
p.R121C | SKCM | 1 |
p.I326M | LUSC | 1 |
p.R713H | STAD | 1 |
p.R690L | UCEC | 1 |
p.R147C | ACC | 1 |
p.D172G | LIHC | 1 |
p.R560* | LUAD | 1 |
p.Y861H | OV | 1 |
p.R121H | BLCA | 1 |
p.D488N | BLCA | 1 |
p.D305E | UCEC | 1 |
p.E413* | CESC | 1 |
p.Q351H | SARC | 1 |
p.E145K | BLCA | 1 |
p.P406S | SKCM | 1 |
p.E496K | SKCM | 1 |
p.R223H | PRAD | 1 |
p.R838L | COAD | 1 |
p.D51N | BLCA | 1 |
p.L101M | UCEC | 1 |
p.R238C | UCEC | 1 |
p.R618Q | THYM | 1 |
p.R204S | UCEC | 1 |
p.G522R | SKCM | 1 |
p.T65R | UCEC | 1 |
p.P547S | SKCM | 1 |
p.C197F | SARC | 1 |
p.F265V | UCEC | 1 |
p.P879T | LUAD | 1 |
p.H141N | ESCA | 1 |
p.R142L | KIRP | 1 |
p.R271Q | SKCM | 1 |
p.D163N | BLCA | 1 |
p.R281H | BLCA | 1 |
p.Y102* | UCEC | 1 |
p.G681C | STAD | 1 |
p.D359N | HNSC | 1 |
p.E166* | CESC | 1 |
p.S658Y | UCEC | 1 |
p.D473N | UCEC | 1 |
p.Q475X | LIHC | 1 |
p.L636S | READ | 1 |
p.L711M | PRAD | 1 |
p.P694L | SKCM | 1 |
p.S354Y | UCEC | 1 |
p.R281C | LGG | 1 |
p.V427I | CESC | 1 |
p.R699X | COAD | 1 |
p.Q314K | HNSC | 1 |
p.R111C | UCEC | 1 |
p.E393K | HNSC | 1 |
p.W701C | SARC | 1 |
p.R783Q | BLCA | 1 |
p.E761G | KIRP | 1 |
p.R4C | STAD | 1 |
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TissGeneCNV for AGBL5 |
![]() (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for AGBL5 |
![]() (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | ChiTaRs | NA | BF985017 | AGBL5-PFAS | chr2:27293467 | chr17:8157319 | |
Chimerdb3.0 | ChiTaRs | NA | BF363390 | AGBL5-CHD5 | chr2:27277662 | chr1:6214740 | |
Chimerdb3.0 | ChiTaRs | NA | BQ276611 | S100A10-AGBL5 | chr1:151955762 | chr2:27293356 | |
Chimerdb3.0 | ChiTaRs | NA | AI825607 | AGBL5-LAMB2P1 | chr2:27282402 | chr3:49191189 |
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TissGeneNet for AGBL5 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for AGBL5 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for AGBL5 |
TissGeneDrug for AGBL5 |
![]() (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for AGBL5 |
![]() (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |