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| TissGeneSummary for RPS9 |
 Gene summary |
| Basic gene information | Gene symbol | RPS9 |
| Gene name | ribosomal protein S9 | |
| Synonyms | S9 | |
| Cytomap | UCSC genome browser: 19q13.4 | |
| Type of gene | protein-coding | |
| RefGenes | NM_001013.3, | |
| Description | 40S ribosomal protein S9 | |
| Modification date | 20141207 | |
| dbXrefs | MIM : 603631 | |
| HGNC : HGNC | ||
| Ensembl : ENSG00000170889 | ||
| HPRD : 04696 | ||
| Vega : OTTHUMG00000066618 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_RPS9 | |
| BioGPS: 6203 | ||
| Pathway | NCI Pathway Interaction Database: RPS9 | |
| KEGG: RPS9 | ||
| REACTOME: RPS9 | ||
| Pathway Commons: RPS9 | ||
| Context | iHOP: RPS9 | |
| ligand binding site mutation search in PubMed: RPS9 | ||
| UCL Cancer Institute: RPS9 | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | TiGER,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Bone marrowOvary | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | LAMLOV | |
| Reference showing the relevant tissue of RPS9 | ||
| Description by TissGene annotations | TissgsLTS Fused withOncogene | |
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
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| TissGeneExp for RPS9 |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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| TissGene-miRNA for RPS9 |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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| TissGeneMut for RPS9 |
| TissGeneSNV for RPS9 |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.V149I | OV | 1 |
| p.G188A | CESC | 1 |
| p.S160F | BLCA | 1 |
| p.T49I | SKCM | 1 |
| p.R138Q | UCEC | 1 |
| p.A51S | ACC | 1 |
| p.T148P | PRAD | 1 |
| p.R133P | PRAD | 1 |
| p.K180N | COAD | 1 |
| p.R79W | COAD | 1 |
| p.D190Y | ESCA | 1 |
| p.R83H | THYM | 1 |
| p.E89D | STAD | 1 |
| p.G118C | KIRC | 1 |
| p.R138W | BLCA | 1 |
| p.R10P | BLCA | 1 |
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| TissGeneCNV for RPS9 |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| TissGeneFusions for RPS9 |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| Chimerdb3.0 | ChiTaRs | NA | CD743028 | SRM-RPS9 | chr1:11116695 | chr19:54705354 | |
| Chimerdb3.0 | ChiTaRs | NA | AW410007 | RPS9-P4HB | chr19:54705054 | chr17:79803074 | |
| Chimerdb3.0 | ChiTaRs | NA | BQ924718 | RPS9-BAIAP2L1 | chr19:54711515 | chr7:98015706 | |
| Chimerdb3.0 | ChiTaRs | NA | BU590293 | RPS9-PSMD4 | chr19:54711372 | chr1:151239761 | |
| Chimerdb3.0 | ChiTaRs | NA | BQ063558 | NPIPB7-RPS9 | chr16:28857600 | chr19:54705436 | |
| Chimerdb3.0 | ChiTaRs | NA | AW771764 | RPS9-ZNF7 | chr19:54711515 | chr8:146067220 |
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| TissGeneNet for RPS9 |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| BRCA (tumor) | BRCA (normal) |
| RPS9, IKBKE, CAND1, CUL5, CUL2, TRAF6, YWHAZ, KIAA0101, VHL, CUL3, LYAR, DSTYK, CUL1, MAP3K14, MEPCE, ADAP1, NOP56, CHAF1A, DDX56, PRKAB1, FTSJ1 (tumor) | RPS9, IKBKE, CAND1, CUL5, CUL2, TRAF6, YWHAZ, VHL, HLA-B, CUL3, MAP3K1, LYAR, STAT3, DSTYK, MAP3K14, MEPCE, ADAP1, NOP56, CHAF1A, DDX56, FTSJ1 (normal) |
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| COAD (tumor) | COAD (normal) |
| RPS9, IKBKE, CAND1, CUL2, SUMO2, KIAA0101, HLA-B, CUL3, ESR1, EIF1B, STAT3, DSTYK, SUMO1, COPS5, CD4, MEPCE, NOP56, MYL12A, DDX56, FTSJ1, PSPH (tumor) | RPS9, CUL5, TRAF6, UBC, SUMO2, KIAA0101, VHL, ESR1, EIF1B, MAP3K1, LYAR, STAT3, DSTYK, SUMO1, COPS5, CD4, MAP3K14, NOP56, DDX56, FTSJ1, PSPH (normal) |
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| HNSC (tumor) | HNSC (normal) |
| RPS9, CAND1, CUL5, CUL2, TRAF6, UBC, SUMO2, VHL, CUL3, ESR1, STAT3, DSTYK, SUMO1, CUL1, COPS5, MEPCE, NOP56, DDX56, MAGEB2, FTSJ1, PSPH (tumor) | RPS9, CAND1, CUL5, CUL2, TRAF6, UBC, SUMO2, KIAA0101, VHL, CUL3, MAP3K1, LYAR, STAT3, DSTYK, SUMO1, CUL1, COPS5, MEPCE, NOP56, MYL12A, DDX56 (normal) |
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| KICH (tumor) | KICH (normal) |
| RPS9, CAND1, CUL5, CUL2, TRAF6, YWHAZ, SUMO2, VHL, EIF1B, MAP3K1, STAT3, DSTYK, SUMO1, TSC22D1, COPS5, MEPCE, MYL12A, CHAF1A, DDX56, FTSJ1, PSPH (tumor) | RPS9, CAND1, CUL5, CUL2, TRAF6, SUMO2, VHL, CUL3, MAP3K1, LYAR, STAT3, DSTYK, SUMO1, TSC22D1, CUL1, MEPCE, NOP56, CHAF1A, DDX56, NDRG1, FTSJ1 (normal) |
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| KIRC (tumor) | KIRC (normal) |
| RPS9, IKBKE, CAND1, CUL5, CUL2, TRAF6, UBC, YWHAZ, SUMO2, VHL, HLA-B, CUL3, MAP3K1, DSTYK, SUMO1, TSC22D1, CUL1, COPS5, ADAP1, MYL12A, FTSJ1 (tumor) | RPS9, IKBKE, CAND1, CUL5, CUL2, TRAF6, UBC, SUMO2, VHL, CUL3, ESR1, MAP3K1, STAT3, DSTYK, COPS5, MEPCE, ADAP1, NOP56, MYL12A, DDX56, FTSJ1 (normal) |
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| KIRP (tumor) | KIRP (normal) |
| RPS9, CAND1, CUL5, TRAF6, UBC, SUMO2, HLA-B, ESR1, EIF1B, LYAR, DSTYK, SUMO1, TSC22D1, CUL1, COPS5, ADAP1, NOP56, MYL12A, CHAF1A, FTSJ1, PSPH (tumor) | RPS9, IKBKE, CAND1, CUL5, CUL2, TRAF6, UBC, SUMO2, KIAA0101, VHL, HLA-B, CUL3, MAP3K1, LYAR, STAT3, DSTYK, SUMO1, COPS5, MEPCE, NOP56, DDX56 (normal) |
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| LIHC (tumor) | LIHC (normal) |
| RPS9, CAND1, CUL5, CUL2, TRAF6, YWHAZ, SUMO2, VHL, HLA-B, CUL3, ESR1, EIF1B, MAP3K1, LYAR, STAT3, SUMO1, COPS5, MEPCE, DDX56, MAGEB2, FTSJ1 (tumor) | RPS9, CAND1, CUL5, CUL2, TRAF6, YWHAZ, SUMO2, VHL, CUL3, ESR1, MAP3K1, LYAR, STAT3, DSTYK, SUMO1, CUL1, COPS5, MEPCE, NOP56, DDX56, FTSJ1 (normal) |
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| LUAD (tumor) | LUAD (normal) |
| RPS9, CUL2, TRAF6, YWHAZ, SUMO2, KIAA0101, VHL, HLA-B, EIF1B, STAT3, DSTYK, SUMO1, COPS5, MAP3K14, MEPCE, MYL12A, CHAF1A, DDX56, MAGEB2, FTSJ1, PSPH (tumor) | RPS9, CAND1, CUL5, TRAF6, SUMO2, VHL, EIF1B, MAP3K1, STAT3, DSTYK, SUMO1, TSC22D1, COPS5, MAP3K14, ADAP1, NOP56, MYL12A, CHAF1A, PRKAB1, MAGEB2, FTSJ1 (normal) |
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| LUSC (tumor) | LUSC (normal) |
| RPS9, CAND1, TRAF6, SUMO2, KIAA0101, VHL, EIF1B, MAP3K1, STAT3, DSTYK, SUMO1, TSC22D1, COPS5, CD4, NOP56, MYL12A, DDX56, PRKAB1, NDRG1, FTSJ1, PSPH (tumor) | RPS9, TRAF6, SUMO2, KIAA0101, VHL, HLA-B, EIF1B, STAT3, DSTYK, SUMO1, TSC22D1, CUL1, COPS5, MEPCE, NOP56, MYL12A, CHAF1A, DDX56, PRKAB1, NDRG1, FTSJ1 (normal) |
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| PRAD (tumor) | PRAD (normal) |
| RPS9, CAND1, CUL5, TRAF6, YWHAZ, SUMO2, KIAA0101, HLA-B, EIF1B, MAP3K1, LYAR, DSTYK, SUMO1, TSC22D1, COPS5, NOP56, MYL12A, DDX56, PRKAB1, MAGEB2, PSPH (tumor) | RPS9, CAND1, CUL5, CUL2, TRAF6, UBC, YWHAZ, SUMO2, VHL, CUL3, MAP3K1, LYAR, STAT3, DSTYK, SUMO1, CD4, MEPCE, ADAP1, NOP56, DDX56, FTSJ1 (normal) |
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| STAD (tumor) | STAD (normal) |
| RPS9, CAND1, TRAF6, UBC, SUMO2, KIAA0101, HLA-B, STAT3, DSTYK, SUMO1, COPS5, MAP3K14, MEPCE, ADAP1, NOP56, MYL12A, DDX56, PRKAB1, MAGEB2, FTSJ1, PSPH (tumor) | RPS9, CAND1, CUL5, CUL2, TRAF6, SUMO2, CUL3, EIF1B, MAP3K1, LYAR, STAT3, DSTYK, CUL1, COPS5, MEPCE, NOP56, MYL12A, CHAF1A, DDX56, PRKAB1, FTSJ1 (normal) |
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| THCA (tumor) | THCA (normal) |
| RPS9, CAND1, CUL5, CUL2, TRAF6, SUMO2, KIAA0101, VHL, HLA-B, CUL3, MAP3K1, LYAR, STAT3, DSTYK, SUMO1, COPS5, NOP56, MYL12A, CHAF1A, DDX56, FTSJ1 (tumor) | RPS9, IKBKE, CAND1, CUL5, CUL2, TRAF6, SUMO2, VHL, HLA-B, CUL3, STAT3, DSTYK, SUMO1, CUL1, MEPCE, ADAP1, NOP56, MYL12A, DDX56, FTSJ1, PSPH (normal) |
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| TissGeneProg for RPS9 |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| TissGeneClin for RPS9 |
| TissGeneDrug for RPS9 |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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| TissGeneDisease for RPS9 |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0008626 | Congenital chromosomal disease | 1 | BeFree |
| umls:C0039263 | Takayasu Arteritis | 1 | BeFree |
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