TissGeneSummary for CT47B1 |
Gene summary |
Basic gene information | Gene symbol | CT47B1 |
Gene name | cancer/testis antigen family 47, member B1 | |
Synonyms | CT47.13|CT47A13 | |
Cytomap | UCSC genome browser: Xq24 | |
Type of gene | protein-coding | |
RefGenes | NM_001145718.1, | |
Description | cancer/testis CT47 family, member 13cancer/testis antigen 47.13cancer/testis antigen 47Bcancer/testis antigen family 147, member B1 | |
Modification date | 20141207 | |
dbXrefs | MIM : 300790 | |
HGNC : HGNC | ||
Ensembl : ENSG00000236446 | ||
Vega : OTTHUMG00000187483 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_CT47B1 | |
BioGPS: 643311 | ||
Pathway | NCI Pathway Interaction Database: CT47B1 | |
KEGG: CT47B1 | ||
REACTOME: CT47B1 | ||
Pathway Commons: CT47B1 | ||
Context | iHOP: CT47B1 | |
ligand binding site mutation search in PubMed: CT47B1 | ||
UCL Cancer Institute: CT47B1 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of CT47B1 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for CT47B1 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for CT47B1 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for CT47B1 |
TissGeneSNV for CT47B1 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.E279K | SKCM | 2 |
p.E258K | LUAD | 1 |
p.E238* | UCEC | 1 |
p.E290K | SKCM | 1 |
p.K226* | HNSC | 1 |
p.E243K | SKCM | 1 |
p.V58L | KIRC | 1 |
p.Q197* | PRAD | 1 |
p.Q77R | CESC | 1 |
p.R133P | LUAD | 1 |
p.A55T | PRAD | 1 |
p.E99D | PAAD | 1 |
p.E98K | SKCM | 1 |
p.D288N | SKCM | 1 |
p.225_226EK>D* | HNSC | 1 |
p.A81T | LUAD | 1 |
p.E278K | SKCM | 1 |
p.G176V | COAD | 1 |
p.R133H | BLCA | 1 |
p.D274N | KIRC | 1 |
p.P257T | LUAD | 1 |
p.E282* | PRAD | 1 |
p.T250S | LUAD | 1 |
p.A193S | LUAD | 1 |
p.R150H | UCEC | 1 |
p.G178E | SKCM | 1 |
p.E233K | SKCM | 1 |
p.E96K | SKCM | 1 |
p.A206V | UCEC | 1 |
p.G71S | LUAD | 1 |
p.A74T | CESC | 1 |
p.E34K | BLCA | 1 |
p.T91M | BRCA | 1 |
p.A111V | UCEC | 1 |
p.S38C | LUAD | 1 |
p.E95D | UCEC | 1 |
p.E279* | HNSC | 1 |
p.P116Q | LUAD | 1 |
p.A219T | LGG | 1 |
p.A157T | ACC | 1 |
p.E243V | CESC | 1 |
p.A215D | ESCA | 1 |
p.E238K | CESC | 1 |
p.Q77R | UCEC | 1 |
p.A215T | SKCM | 1 |
p.Q142* | SKCM | 1 |
p.V196I | UCEC | 1 |
p.G36S | HNSC | 1 |
p.E242K | SKCM | 1 |
p.D37Y | LGG | 1 |
p.G79A | LUAD | 1 |
p.E247D | UCEC | 1 |
p.A70T | HNSC | 1 |
p.A103V | CESC | 1 |
p.E217K | HNSC | 1 |
p.G188S | STAD | 1 |
p.T237K | LUAD | 1 |
p.T91M | SKCM | 1 |
p.E238K | SKCM | 1 |
p.G39D | SKCM | 1 |
p.H137Y | BLCA | 1 |
p.A232T | COAD | 1 |
p.E93K | SKCM | 1 |
p.E198G | DLBC | 1 |
p.P257H | LUAD | 1 |
p.E225D | LUAD | 1 |
p.R113S | LUAD | 1 |
p.V58G | LUAD | 1 |
p.S195X | COAD | 1 |
p.G176A | COAD | 1 |
p.P249L | THCA | 1 |
p.S195L | UCEC | 1 |
p.E252Q | BLCA | 1 |
p.S251T | HNSC | 1 |
p.A103V | LUAD | 1 |
p.E258D | LUAD | 1 |
p.E238Q | LUAD | 1 |
p.G53E | SKCM | 1 |
p.P244S | HNSC | 1 |
p.E229K | SKCM | 1 |
p.A199V | LUAD | 1 |
p.E185K | SKCM | 1 |
p.A223T | COAD | 1 |
p.E271D | LUAD | 1 |
p.P249L | SKCM | 1 |
p.G188D | SKCM | 1 |
p.E225D | HNSC | 1 |
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TissGeneCNV for CT47B1 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for CT47B1 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for CT47B1 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for CT47B1 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for CT47B1 |
TissGeneDrug for CT47B1 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for CT47B1 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |