TissGeneSummary for CTAGE1 |
Gene summary |
Basic gene information | Gene symbol | CTAGE1 |
Gene name | cutaneous T-cell lymphoma-associated antigen 1 | |
Synonyms | CT21.1|CT21.2|CTAGE|CTAGE-1|CTAGE-2 | |
Cytomap | UCSC genome browser: 18p11.2 | |
Type of gene | protein-coding | |
RefGenes | NM_022663.1, NM_172241.2, | |
Description | cTAGE family member 2cancer/testis antigen 21.2cancer/testis antigen family 21, member 1cancer/testis antigen family 21, member 2cutaneous T-cell lymphoma-associated antigen 2protein cTAGE-2 | |
Modification date | 20141207 | |
dbXrefs | MIM : 608856 | |
HGNC : HGNC | ||
Ensembl : ENSG00000212710 | ||
HPRD : 16395 | ||
Vega : OTTHUMG00000165867 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_CTAGE1 | |
BioGPS: 64693 | ||
Pathway | NCI Pathway Interaction Database: CTAGE1 | |
KEGG: CTAGE1 | ||
REACTOME: CTAGE1 | ||
Pathway Commons: CTAGE1 | ||
Context | iHOP: CTAGE1 | |
ligand binding site mutation search in PubMed: CTAGE1 | ||
UCL Cancer Institute: CTAGE1 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of CTAGE1 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for CTAGE1 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for CTAGE1 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for CTAGE1 |
TissGeneSNV for CTAGE1 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.S155L | SKCM | 2 |
p.G544E | SKCM | 2 |
p.S152F | SKCM | 2 |
p.W182* | SKCM | 2 |
p.P701L | SKCM | 1 |
p.F739S | ESCA | 1 |
p.P471S | SKCM | 1 |
p.P734Q | LUAD | 1 |
p.M390I | SKCM | 1 |
p.A405S | LUAD | 1 |
p.C117S | ESCA | 1 |
p.G544V | LUSC | 1 |
p.P589L | SKCM | 1 |
p.E374Q | LUAD | 1 |
p.K409* | ESCA | 1 |
p.K409X | ESCA | 1 |
p.R720I | UCEC | 1 |
p.E102K | UCEC | 1 |
p.E88K | HNSC | 1 |
p.G489D | SKCM | 1 |
p.S586* | CESC | 1 |
p.D257N | SKCM | 1 |
p.E459K | SKCM | 1 |
p.R173W | KIRP | 1 |
p.S67N | SKCM | 1 |
p.G685R | BLCA | 1 |
p.P531A | SKCM | 1 |
p.E119D | LIHC | 1 |
p.A565T | KIRC | 1 |
p.L111V | LUAD | 1 |
p.P492T | LUAD | 1 |
p.Q205* | BLCA | 1 |
p.R735S | GBM | 1 |
p.F697L | CESC | 1 |
p.F739S | STAD | 1 |
p.Q419X | SKCM | 1 |
p.L672F | OV | 1 |
p.P584S | SKCM | 1 |
p.Q349K | LUAD | 1 |
p.G301E | SKCM | 1 |
p.R556K | SKCM | 1 |
p.E389K | UCEC | 1 |
p.K420T | BLCA | 1 |
p.E374K | SKCM | 1 |
p.F164S | PAAD | 1 |
p.P650L | SKCM | 1 |
p.S269L | KIRC | 1 |
p.A715V | COAD | 1 |
p.P487A | LUAD | 1 |
p.M620I | SKCM | 1 |
p.E654K | HNSC | 1 |
p.E410K | SKCM | 1 |
p.Y488H | UCEC | 1 |
p.A436V | STAD | 1 |
p.P567S | LUAD | 1 |
p.P725Q | HNSC | 1 |
p.E102K | SKCM | 1 |
p.R368M | COAD | 1 |
p.L639I | UCEC | 1 |
p.P662S | SKCM | 1 |
p.P710S | SKCM | 1 |
p.R106K | SKCM | 1 |
p.W182X | SKCM | 1 |
p.T256M | LGG | 1 |
p.F28L | UCEC | 1 |
p.A587T | SKCM | 1 |
p.E373K | HNSC | 1 |
p.G524E | LUAD | 1 |
p.G281* | PRAD | 1 |
p.D549N | HNSC | 1 |
p.K284* | LUAD | 1 |
p.R735I | UCEC | 1 |
p.L639I | BRCA | 1 |
p.E121* | UCEC | 1 |
p.S503P | CESC | 1 |
p.R214K | SKCM | 1 |
p.E79D | BLCA | 1 |
p.E149V | BLCA | 1 |
p.S546X | KIRC | 1 |
p.E410* | UCEC | 1 |
p.P487S | SKCM | 1 |
p.W202R | LUAD | 1 |
p.G698* | STAD | 1 |
p.F576C | BLCA | 1 |
p.K315E | UCEC | 1 |
p.E114K | SKCM | 1 |
p.M1I | CESC | 1 |
p.E124K | SKCM | 1 |
p.L261M | CESC | 1 |
p.P662A | HNSC | 1 |
p.D634N | SKCM | 1 |
p.R402Q | STAD | 1 |
p.P645S | LGG | 1 |
p.R214S | OV | 1 |
p.I143T | PRAD | 1 |
p.E184K | SKCM | 1 |
p.E264* | UCEC | 1 |
p.D445N | SKCM | 1 |
p.A435S | LUSC | 1 |
p.E171K | HNSC | 1 |
p.R44T | BLCA | 1 |
p.S647L | SKCM | 1 |
p.A158G | TGCT | 1 |
p.E200K | LUAD | 1 |
p.D246N | SKCM | 1 |
p.E64K | SKCM | 1 |
p.P740L | LUSC | 1 |
p.E131D | LUSC | 1 |
p.P689S | SKCM | 1 |
p.W433R | UCEC | 1 |
p.Q168E | BLCA | 1 |
p.D621N | SKCM | 1 |
p.Q419* | SKCM | 1 |
p.K420N | UCEC | 1 |
p.V722I | STAD | 1 |
p.M162I | SKCM | 1 |
p.Q189K | LUAD | 1 |
p.K243R | OV | 1 |
p.S140F | SKCM | 1 |
p.W12L | STAD | 1 |
p.E300* | UCEC | 1 |
p.R173W | STAD | 1 |
p.D4N | COAD | 1 |
p.N326I | GBM | 1 |
p.R17H | STAD | 1 |
p.L504F | SKCM | 1 |
p.P279L | SKCM | 1 |
p.P531L | SKCM | 1 |
p.E190K | SKCM | 1 |
p.R402Q | PAAD | 1 |
p.Q346* | LGG | 1 |
p.E322K | UCEC | 1 |
p.R550T | HNSC | 1 |
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TissGeneCNV for CTAGE1 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for CTAGE1 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for CTAGE1 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for CTAGE1 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for CTAGE1 |
TissGeneDrug for CTAGE1 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for CTAGE1 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0079773 | Lymphoma, T-Cell, Cutaneous | 2 | BeFree,LHGDN |
umls:C0006111 | Brain Diseases | 1 | GAD |