Basic gene information | Gene symbol | SSX2 |
Gene name | synovial sarcoma, X breakpoint 2 |
Synonyms | CT5.2|CT5.2A|HD21|HOM-MEL-40|SSX |
Cytomap | UCSC genome browser: Xp11.22 |
Type of gene | protein-coding |
RefGenes | NM_001278697.1, NM_003147.5,NM_175698.2, |
Description | cancer/testis antigen 5.2cancer/testis antigen family 5, member 2aprotein SSX2sarcoma, synovial, X-chromosome-related 2synovial sarcoma, X breakpoint 2Btumor antigen HOM-MEL-40 |
Modification date | 20141222 |
dbXrefs | MIM : 300192 |
HGNC : HGNC |
Ensembl : ENSG00000241476 |
HPRD : 02180 |
Vega : OTTHUMG00000022697 |
Protein | UniProt: go to UniProt's Cross Reference DB Table |
Expression | CleanEX: HS_SSX2 |
BioGPS: 6757 |
Pathway | NCI Pathway Interaction Database: SSX2 |
KEGG: SSX2 |
REACTOME: SSX2 |
Pathway Commons: SSX2 |
Context | iHOP: SSX2 |
ligand binding site mutation search in PubMed: SSX2 |
UCL Cancer Institute: SSX2 |
Assigned class in TissGDB* | A |
Included tissue-specific gene expression resources | HPA,TiGER,GTEx |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | SkinTestis |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | SKCMTGCT |
Reference showing the relevant tissue of SSX2 | Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer.Cancer Res. 2011 Nov 1;71(21):6785-95. doi: 10.1158/0008-5472.CAN-11-2127. (pmid:21880588) go to article |
Description by TissGene annotations | Cancer gene Fused withOncogene
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BRCA (tumor) | BRCA (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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COAD (tumor) | COAD (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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HNSC (tumor) | HNSC (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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KICH (tumor) | KICH (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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KIRC (tumor) | KIRC (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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KIRP (tumor) | KIRP (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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LIHC (tumor) | LIHC (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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LUAD (tumor) | LUAD (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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LUSC (tumor) | LUSC (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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PRAD (tumor) | PRAD (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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STAD (tumor) | STAD (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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THCA (tumor) | THCA (normal) |
SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (tumor) | SSX2, SMARCA2, RNF2, SSX2IP, RAB3IP (normal) |
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Disease ID | Disease name | # pubmeds | Source |
umls:C0039101 | synovial sarcoma | 128 | BeFree,CTD_human,LHGDN,ORPHANET |
umls:C0153594 | Malignant neoplasm of testis | 21 | BeFree |
umls:C1261473 | Sarcoma | 17 | BeFree |
umls:C0025202 | melanoma | 10 | BeFree |
umls:C0596263 | Carcinogenesis | 10 | BeFree |
umls:C0027627 | Neoplasm Metastasis | 7 | BeFree |
umls:C0006142 | Malignant neoplasm of breast | 6 | BeFree |
umls:C0037579 | Soft Tissue Neoplasms | 4 | BeFree |
umls:C0334507 | Synovial sarcoma, biphasic | 4 | BeFree |
umls:C0678222 | Breast Carcinoma | 4 | BeFree |
umls:C1334801 | Monophasic Synovial Sarcoma | 3 | BeFree |
umls:C0026764 | Multiple Myeloma | 2 | BeFree |
umls:C0376358 | Malignant neoplasm of prostate | 2 | BeFree |
umls:C0600139 | Prostate carcinoma | 2 | BeFree |
umls:C0751690 | Malignant Peripheral Nerve Sheath Tumor | 2 | BeFree |
umls:C0855071 | Synovial sarcoma non-metastatic | 2 | BeFree |
umls:C1527249 | Colorectal Cancer | 2 | BeFree |
umls:C0007102 | Malignant tumor of colon | 1 | BeFree |
umls:C0014859 | Esophageal Neoplasms | 1 | BeFree |
umls:C0023467 | Leukemia, Myelocytic, Acute | 1 | BeFree |
umls:C0023470 | Myeloid Leukemia | 1 | BeFree |
umls:C0024299 | Lymphoma | 1 | BeFree |
umls:C0026470 | Monoclonal Gammopathy of Undetermined Significance | 1 | BeFree |
umls:C0029463 | Osteosarcoma | 1 | BeFree |
umls:C0031117 | Peripheral Neuropathy | 1 | CTD_human |
umls:C0033578 | Prostatic Neoplasms | 1 | CTD_human |
umls:C0035412 | Rhabdomyosarcoma | 1 | BeFree |
umls:C0036631 | Seminoma | 1 | BeFree |
umls:C0086692 | Benign Neoplasm | 1 | BeFree |
umls:C0152018 | Esophageal carcinoma | 1 | BeFree |
umls:C0153676 | Secondary malignant neoplasm of lung | 1 | BeFree |
umls:C0205748 | Dysplastic Nevus | 1 | BeFree |
umls:C0334471 | Round cell liposarcoma | 1 | BeFree |
umls:C0546837 | Malignant neoplasm of esophagus | 1 | BeFree |
umls:C0585442 | Osteosarcoma of bone | 1 | BeFree |
umls:C0936223 | Metastatic Prostate Carcinoma | 1 | BeFree |
umls:C1275278 | Extraskeletal Myxoid Chondrosarcoma | 1 | BeFree |
umls:C1334699 | Mesenchymal Cell Neoplasm | 1 | BeFree |
umls:C2239176 | Liver carcinoma | 1 | BeFree,LHGDN |