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| TissGeneSummary for BUB1 |
 Gene summary |
| Basic gene information | Gene symbol | BUB1 |
| Gene name | BUB1 mitotic checkpoint serine/threonine kinase | |
| Synonyms | BUB1A|BUB1L|hBUB1 | |
| Cytomap | UCSC genome browser: 2q14 | |
| Type of gene | protein-coding | |
| RefGenes | NM_001278616.1, NM_001278617.1,NM_004336.4, | |
| Description | BUB1 budding uninhibited by benzimidazoles 1 homologbudding uninhibited by benzimidazoles 1 homologmitotic checkpoint serine/threonine-protein kinase BUB1mitotic spindle checkpoint kinaseputative serine/threonine-protein kinase | |
| Modification date | 20141207 | |
| dbXrefs | MIM : 602452 | |
| HGNC : HGNC | ||
| Ensembl : ENSG00000169679 | ||
| HPRD : 03907 | ||
| Vega : OTTHUMG00000153638 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_BUB1 | |
| BioGPS: 699 | ||
| Pathway | NCI Pathway Interaction Database: BUB1 | |
| KEGG: BUB1 | ||
| REACTOME: BUB1 | ||
| Pathway Commons: BUB1 | ||
| Context | iHOP: BUB1 | |
| ligand binding site mutation search in PubMed: BUB1 | ||
| UCL Cancer Institute: BUB1 | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | TiGER,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
| Reference showing the relevant tissue of BUB1 | ||
| Description by TissGene annotations | Cancer gene | |
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID | GO:0007063 | regulation of sister chromatid cohesion | 15723797 | GO:0071173 | spindle assembly checkpoint | 15020684 | GO:0007063 | regulation of sister chromatid cohesion | 15723797 | GO:0071173 | spindle assembly checkpoint | 15020684 |
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| TissGeneExp for BUB1 |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| KIRC | -0.797914883 | -3.970674605 | 3.172759722 | 4.21E-30 | 8.00E-29 |
| KICH | -1.353179883 | -4.158727883 | 2.805548 | 1.75E-07 | 7.68E-07 |
| STAD | 1.965703867 | -0.987596133 | 2.9533 | 3.68E-07 | 7.46E-06 |
| KIRP | -1.025986758 | -4.509383633 | 3.483396875 | 2.37E-12 | 3.64E-11 |
| LUAD | 1.174511841 | -1.557791607 | 2.732303448 | 1.25E-22 | 3.55E-21 |
| HNSC | 2.031583373 | 0.203834536 | 1.827748837 | 1.80E-10 | 3.48E-09 |
| COAD | 2.197994732 | 0.706990886 | 1.491003846 | 3.32E-09 | 3.32E-08 |
| LUSC | 2.286022862 | -1.430965373 | 3.716988235 | 2.04E-35 | 2.87E-33 |
| PRAD | -1.752951421 | -3.106311037 | 1.353359615 | 2.84E-07 | 2.31E-06 |
| LIHC | -0.392077883 | -4.274043883 | 3.881966 | 8.41E-25 | 1.56E-22 |
| BRCA | 1.372086433 | -2.235653041 | 3.607739474 | 5.33E-55 | 1.09E-52 |
| THCA | -1.580258527 | -3.358080561 | 1.777822034 | 2.49E-07 | 1.03E-06 |
| ESCA | 2.358105572 | -1.558485337 | 3.916590909 | 5.86E-05 | 0.002183895 |
| BLCA | 2.390070643 | -0.962792515 | 3.352863158 | 5.44E-06 | 0.000119788 |
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| TissGene-miRNA for BUB1 |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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| TissGeneMut for BUB1 |
| TissGeneSNV for BUB1 |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.E536* | UCEC | 2 |
| p.K279E | LGG | 2 |
| p.R657C | SKCM | 2 |
| p.R820* | LUAD | 1 |
| p.P364S | THYM | 1 |
| p.D952H | BRCA | 1 |
| p.S459P | KICH | 1 |
| p.K299E | LGG | 1 |
| p.S752F | SKCM | 1 |
| p.K299T | STAD | 1 |
| p.I197M | READ | 1 |
| p.E23Q | LUAD | 1 |
| p.V863L | STAD | 1 |
| p.M933I | BLCA | 1 |
| p.S647L | SKCM | 1 |
| p.Q816* | KIRP | 1 |
| p.R677C | UCEC | 1 |
| p.T392K | UCEC | 1 |
| p.M428V | BLCA | 1 |
| p.A337V | STAD | 1 |
| p.R585H | STAD | 1 |
| p.S174* | BLCA | 1 |
| p.E746Q | BLCA | 1 |
| p.K824T | LUSC | 1 |
| p.S203* | LUAD | 1 |
| p.T785I | LIHC | 1 |
| p.S667L | STAD | 1 |
| p.C641F | LUSC | 1 |
| p.L678V | BLCA | 1 |
| p.Q505E | CESC | 1 |
| p.K61N | SKCM | 1 |
| p.A630E | UCEC | 1 |
| p.E535K | LUAD | 1 |
| p.S230P | SKCM | 1 |
| p.S491T | LGG | 1 |
| p.H649D | HNSC | 1 |
| p.T552I | UCEC | 1 |
| p.S667L | READ | 1 |
| p.D890Y | BLCA | 1 |
| p.E573K | SKCM | 1 |
| p.E701* | LGG | 1 |
| p.G195A | BLCA | 1 |
| p.H915R | UCEC | 1 |
| p.R1062C | LUAD | 1 |
| p.E394K | HNSC | 1 |
| p.G554R | STAD | 1 |
| p.A696V | LUAD | 1 |
| p.R146H | COAD | 1 |
| p.P805T | PAAD | 1 |
| p.F38L | CESC | 1 |
| p.Q325E | BLCA | 1 |
| p.F575V | BLCA | 1 |
| p.N534S | OV | 1 |
| p.V626A | LUAD | 1 |
| p.P542S | SKCM | 1 |
| p.L1073I | ESCA | 1 |
| p.C698Y | GBM | 1 |
| p.F971C | UCEC | 1 |
| p.E36D | STAD | 1 |
| p.V362F | STAD | 1 |
| p.E43Q | LUAD | 1 |
| p.Q871* | HNSC | 1 |
| p.L147F | LUSC | 1 |
| p.L658V | BLCA | 1 |
| p.L820V | HNSC | 1 |
| p.H1023Y | SKCM | 1 |
| p.M472I | CESC | 1 |
| p.S582C | BLCA | 1 |
| p.H131P | SKCM | 1 |
| p.Q803* | SKCM | 1 |
| p.L882F | LGG | 1 |
| p.I707S | STAD | 1 |
| p.V201M | PAAD | 1 |
| p.P355T | COAD | 1 |
| p.P339H | SKCM | 1 |
| p.P828S | SKCM | 1 |
| p.K945N | LUAD | 1 |
| p.Q345E | BLCA | 1 |
| p.R677C | CESC | 1 |
| p.E50K | COAD | 1 |
| p.Q302P | BLCA | 1 |
| p.E548K | BLCA | 1 |
| p.A13V | LUAD | 1 |
| p.P808S | SKCM | 1 |
| p.R317G | UCEC | 1 |
| p.P957S | SKCM | 1 |
| p.H1023Q | BLCA | 1 |
| p.P562S | SKCM | 1 |
| p.E414K | HNSC | 1 |
| p.D45N | HNSC | 1 |
| p.F818V | UCEC | 1 |
| p.H63Y | SKCM | 1 |
| p.S156L | SKCM | 1 |
| p.S223* | LUAD | 1 |
| p.G583A | DLBC | 1 |
| p.P825T | PAAD | 1 |
| p.S437Y | UCEC | 1 |
| p.R244C | UCEC | 1 |
| p.V221M | PAAD | 1 |
| p.S647L | STAD | 1 |
| p.Q985K | LUSC | 1 |
| p.E233* | BLCA | 1 |
| p.L122I | STAD | 1 |
| p.Q456R | BLCA | 1 |
| p.A317V | PRAD | 1 |
| p.E690D | STAD | 1 |
| p.M1015T | MESO | 1 |
| p.K41N | SKCM | 1 |
| p.L800V | HNSC | 1 |
| p.Q282P | BLCA | 1 |
| p.E129K | BLCA | 1 |
| p.R137T | ESCA | 1 |
| p.G175A | BLCA | 1 |
| p.I1074M | STAD | 1 |
| p.K965N | LUAD | 1 |
| p.A358V | LAML | 1 |
| p.F923L | UCEC | 1 |
| p.E775K | SKCM | 1 |
| p.A183T | UCEC | 1 |
| p.R677C | SKCM | 1 |
| p.H1043Q | BLCA | 1 |
| p.Q796* | KIRP | 1 |
| p.P937S | SKCM | 1 |
| p.S732F | SKCM | 1 |
| p.R157T | ESCA | 1 |
| p.F75C | READ | 1 |
| p.E553K | SKCM | 1 |
| p.Q398H | BLCA | 1 |
| p.D987N | COAD | 1 |
| p.P438Q | PRAD | 1 |
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| TissGeneCNV for BUB1 |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| TissGeneFusions for BUB1 |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| Chimerdb3.0 | ChiTaRs | NA | AU119852 | BUB1-RGS2 | chr2:111430434 | chr1:192780565 | |
| Chimerdb3.0 | ChiTaRs | NA | BG403632 | BUB1-BUB1 | chr2:111395628 | chr2:111395409 |
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| TissGeneNet for BUB1 |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| BRCA (tumor) | BRCA (normal) |
| BUB1, TP53, PLK1, HDAC3, HDAC1, CDK1, DSN1, NUF2, NDC80, BUB1B, ZWINT, AP1B1, RDH12, SIRT5, SPC24, BUB3, RAE1, CDC20, AP2B1, SPC25, CASC5 (tumor) | BUB1, PLK1, HDAC1, PIN1, CDK1, DSN1, NUF2, NDC80, BUB1B, ZWINT, RDH12, SIRT5, EIF4EBP1, SPC24, UBR5, BUB3, RAE1, CDC20, ZW10, SPC25, CASC5 (normal) |
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| COAD (tumor) | COAD (normal) |
| BUB1, TP53, PLK1, SVIL, HDAC1, CDK1, DSN1, NUF2, NDC80, BUB1B, ARIH2, ZWINT, SPC24, BUB3, RAE1, CDC20, AP2B1, ZW10, SPC25, AP3B1, CASC5 (tumor) | BUB1, PLK1, HDAC3, SVIL, HDAC1, CDK1, DSN1, NUF2, NDC80, BUB1B, ZWINT, NSL1, EIF4EBP1, SPC24, BUB3, CDC20, MIS12, AP2B1, ZW10, SPC25, CASC5 (normal) |
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| HNSC (tumor) | HNSC (normal) |
| BUB1, TP53, PLK1, HDAC1, CDK1, DSN1, NUF2, NDC80, BUB1B, ZWINT, AP1B1, RDH12, SPC24, NDEL1, BUB3, RAE1, CDC20, ZW10, SPC25, AP3B1, CASC5 (tumor) | BUB1, APC, PLK1, CDK1, DSN1, NUF2, NDC80, BUB1B, ZWINT, RDH12, NSL1, SPC24, UBR5, NDEL1, BUB3, CDC20, MIS12, AP2B1, ZW10, SPC25, CASC5 (normal) |
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| KICH (tumor) | KICH (normal) |
| BUB1, TP53, APC, PLK1, HDAC3, SVIL, PIN1, CDK1, NUF2, NDC80, BUB1B, ARIH2, PMF1, SIRT5, SPC24, NDEL1, RAE1, CDC20, AP2B1, SPC25, AP4B1 (tumor) | BUB1, TP53, APC, PLK1, HDAC3, HDAC1, CDK1, NUF2, NDC80, BUB1B, CRK, ZWINT, SIRT5, EIF4EBP1, SPC24, UBR5, CDC20, ZW10, SPC25, AP3B1, CASC5 (normal) |
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| KIRC (tumor) | KIRC (normal) |
| BUB1, TP53, PLK1, SVIL, CDK1, DSN1, NUF2, NDC80, BUB1B, ARIH2, ZWINT, PMF1, SIRT5, EIF4EBP1, SPC24, BUB3, CDC20, MIS12, ZW10, SPC25, AP4B1 (tumor) | BUB1, PLK1, HDAC3, PIN1, CDK1, DSN1, NUF2, NDC80, BUB1B, CRK, ZWINT, PMF1, SIRT5, SPC24, UBR5, BUB3, RAE1, CDC20, ZW10, SPC25, CASC5 (normal) |
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| KIRP (tumor) | KIRP (normal) |
| BUB1, TP53, PLK1, SVIL, PIN1, CDK1, NUF2, NDC80, BUB1B, ARIH2, NSL1, PMF1, SIRT5, SPC24, NDEL1, BUB3, CDC20, AP2B1, ZW10, SPC25, AP4B1 (tumor) | BUB1, PLK1, HDAC3, CDK1, DSN1, NUF2, NDC80, BUB1B, ARIH2, ZWINT, NSL1, SIRT5, SPC24, UBR5, BUB3, RAE1, CDC20, MIS12, ZW10, SPC25, CASC5 (normal) |
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| LIHC (tumor) | LIHC (normal) |
| BUB1, APC, PLK1, HDAC1, CDK1, DSN1, NUF2, NDC80, BUB1B, ZWINT, NSL1, EIF4EBP1, UBR5, BUB3, CDC20, MIS12, AP2B1, SPC25, AP3B1, AP4B1, CASC5 (tumor) | BUB1, PLK1, HDAC1, CDK1, DSN1, NUF2, NDC80, BUB1B, ARIH2, ZWINT, SIRT5, SPC24, UBR5, NDEL1, BUB3, RAE1, CDC20, ZW10, SPC25, AP3B1, CASC5 (normal) |
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| LUAD (tumor) | LUAD (normal) |
| BUB1, TP53, APC, PLK1, HDAC3, HDAC1, CDK1, NUF2, NDC80, BUB1B, ZWINT, AP1B1, RDH12, PMF1, EIF4EBP1, NDEL1, BUB3, RAE1, CDC20, SPC25, CASC5 (tumor) | BUB1, TP53, APC, PLK1, HDAC1, CDK1, DSN1, NUF2, NDC80, BUB1B, ZWINT, PMF1, EIF4EBP1, SPC24, UBR5, BUB3, RAE1, CDC20, ZW10, SPC25, CASC5 (normal) |
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| LUSC (tumor) | LUSC (normal) |
| BUB1, TP53, PLK1, HDAC3, HDAC1, CDK1, DSN1, NUF2, NDC80, BUB1B, CRK, ZWINT, NSL1, EIF4EBP1, SPC24, NDEL1, BUB3, CDC20, SPC25, AP3B1, CASC5 (tumor) | BUB1, PLK1, CDK1, DSN1, NUF2, NDC80, BUB1B, ZWINT, NSL1, PMF1, SIRT5, SPC24, NDEL1, BUB3, RAE1, CDC20, MIS12, AP2B1, ZW10, SPC25, CASC5 (normal) |
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| PRAD (tumor) | PRAD (normal) |
| BUB1, TP53, APC, PLK1, HDAC3, PIN1, NUF2, BUB1B, CRK, ZWINT, NSL1, EIF4EBP1, SPC24, BUB3, RAE1, CDC20, MIS12, AP2B1, SPC25, AP3B1, CASC5 (tumor) | BUB1, PLK1, SVIL, PIN1, CDK1, DSN1, NUF2, NDC80, BUB1B, ZWINT, AP1B1, NSL1, PMF1, SPC24, UBR5, NDEL1, BUB3, CDC20, ZW10, SPC25, CASC5 (normal) |
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| STAD (tumor) | STAD (normal) |
| BUB1, TP53, PLK1, SVIL, HDAC1, CDK1, DSN1, NUF2, NDC80, BUB1B, ARIH2, ZWINT, AP1B1, RDH12, EIF4EBP1, SPC24, CDC20, SPC25, AP3B1, AP4B1, CASC5 (tumor) | BUB1, PLK1, SVIL, HDAC1, PIN1, CDK1, DSN1, NUF2, NDC80, BUB1B, ZWINT, EIF4EBP1, SPC24, UBR5, BUB3, RAE1, CDC20, AP2B1, ZW10, SPC25, CASC5 (normal) |
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| THCA (tumor) | THCA (normal) |
| BUB1, TP53, PLK1, SVIL, CDK1, DSN1, NUF2, NDC80, BUB1B, ARIH2, ZWINT, AP1B1, SIRT5, EIF4EBP1, SPC24, BUB3, CDC20, AP2B1, SPC25, AP3B1, CASC5 (tumor) | BUB1, PLK1, SVIL, HDAC1, CDK1, DSN1, NUF2, NDC80, BUB1B, ARIH2, ZWINT, SIRT5, EIF4EBP1, SPC24, NDEL1, BUB3, CDC20, ZW10, SPC25, AP4B1, CASC5 (normal) |
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| TissGeneProg for BUB1 |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| TissGeneClin for BUB1 |
| TissGeneDrug for BUB1 |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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| TissGeneDisease for BUB1 |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0596263 | Carcinogenesis | 9 | BeFree |
| umls:C1527249 | Colorectal Cancer | 9 | BeFree |
| umls:C0027126 | Myotonic Dystrophy | 7 | BeFree |
| umls:C0410226 | Congenital Myotonic Dystrophy | 7 | BeFree |
| umls:C0006142 | Malignant neoplasm of breast | 5 | BeFree,GAD |
| umls:C0678222 | Breast Carcinoma | 5 | BeFree |
| umls:C0009402 | Colorectal Carcinoma | 4 | BeFree |
| umls:C0023418 | leukemia | 4 | BeFree,LHGDN |
| umls:C0699791 | Stomach Carcinoma | 4 | BeFree |
| umls:C0009404 | Colorectal Neoplasms | 3 | BeFree,LHGDN |
| umls:C0024623 | Malignant neoplasm of stomach | 3 | BeFree |
| umls:C0027627 | Neoplasm Metastasis | 3 | BeFree |
| umls:C0001418 | Adenocarcinoma | 2 | BeFree |
| umls:C0017636 | Glioblastoma | 2 | BeFree |
| umls:C0023467 | Leukemia, Myelocytic, Acute | 2 | BeFree,LHGDN |
| umls:C0178874 | Tumor Progression | 2 | BeFree |
| umls:C0242379 | Malignant neoplasm of lung | 2 | BeFree |
| umls:C0549473 | Thyroid carcinoma | 2 | BeFree |
| umls:C0598766 | Leukemogenesis | 2 | BeFree |
| umls:C0684249 | Carcinoma of lung | 2 | BeFree |
| umls:C0699790 | Colon Carcinoma | 2 | BeFree,CLINVAR |
| umls:C1140680 | Malignant neoplasm of ovary | 2 | BeFree,GAD |
| umls:C0001973 | Alcoholic Intoxication, Chronic | 1 | GAD |
| umls:C0004763 | Barrett Esophagus | 1 | LHGDN |
| umls:C0005695 | Bladder Neoplasm | 1 | BeFree |
| umls:C0007102 | Malignant tumor of colon | 1 | BeFree |
| umls:C0007115 | Malignant neoplasm of thyroid | 1 | BeFree |
| umls:C0007131 | Non-Small Cell Lung Carcinoma | 1 | BeFree |
| umls:C0011849 | Diabetes Mellitus | 1 | BeFree |
| umls:C0017661 | IGA Glomerulonephritis | 1 | CTD_human |
| umls:C0023448 | Lymphoid leukemia | 1 | BeFree |
| umls:C0023449 | Acute lymphocytic leukemia | 1 | BeFree |
| umls:C0023493 | Adult T-Cell Lymphoma/Leukemia | 1 | BeFree |
| umls:C0024121 | Lung Neoplasms | 1 | BeFree |
| umls:C0024299 | Lymphoma | 1 | BeFree,LHGDN |
| umls:C0026764 | Multiple Myeloma | 1 | BeFree |
| umls:C0029925 | Ovarian Carcinoma | 1 | BeFree |
| umls:C0030297 | Pancreatic Neoplasm | 1 | LHGDN |
| umls:C0031269 | Peutz-Jeghers Syndrome | 1 | BeFree |
| umls:C0040136 | Thyroid Neoplasm | 1 | LHGDN |
| umls:C0206708 | Cervical Intraepithelial Neoplasia | 1 | BeFree |
| umls:C0235974 | Pancreatic carcinoma | 1 | BeFree |
| umls:C0280100 | Solid tumour | 1 | BeFree |
| umls:C0334588 | Giant Cell Glioblastoma | 1 | BeFree |
| umls:C0346647 | Malignant neoplasm of pancreas | 1 | BeFree |
| umls:C0376358 | Malignant neoplasm of prostate | 1 | BeFree |
| umls:C0474808 | Follicular neoplasm | 1 | BeFree |
| umls:C0600139 | Prostate carcinoma | 1 | BeFree |
| umls:C0686619 | Secondary malignant neoplasm of lymph node | 1 | BeFree |
| umls:C1168401 | Squamous cell carcinoma of the head and neck | 1 | BeFree |
| umls:C1261473 | Sarcoma | 1 | BeFree |
| umls:C1335177 | Ovarian Serous Adenocarcinoma | 1 | BeFree |
| umls:C1654637 | androgen independent prostate cancer | 1 | BeFree |
| umls:C1961102 | Precursor Cell Lymphoblastic Leukemia Lymphoma | 1 | BeFree |
| umls:C2239176 | Liver carcinoma | 1 | BeFree |
| umls:C1850343 | MOSAIC VARIEGATED ANEUPLOIDY SYNDROME | 0 | ORPHANET |
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