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| TissGeneSummary for TF |
 Gene summary |
| Basic gene information | Gene symbol | TF |
| Gene name | transferrin | |
| Synonyms | PRO1557|PRO2086|TFQTL1 | |
| Cytomap | UCSC genome browser: 3q22.1 | |
| Type of gene | protein-coding | |
| RefGenes | NM_001063.3, | |
| Description | beta-1 metal-binding globulinserotransferrinsiderophilin | |
| Modification date | 20141207 | |
| dbXrefs | MIM : 190000 | |
| HGNC : HGNC | ||
| Ensembl : ENSG00000091513 | ||
| HPRD : 01811 | ||
| Vega : OTTHUMG00000150356 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_TF | |
| BioGPS: 7018 | ||
| Pathway | NCI Pathway Interaction Database: TF | |
| KEGG: TF | ||
| REACTOME: TF | ||
| Pathway Commons: TF | ||
| Context | iHOP: TF | |
| ligand binding site mutation search in PubMed: TF | ||
| UCL Cancer Institute: TF | ||
| Assigned class in TissGDB* | B | |
| Included tissue-specific gene expression resources | HPA,TiGER,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | LiverEye | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | LIHCUVM | |
| Reference showing the relevant tissue of TF | ||
| Description by TissGene annotations | ||
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
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| TissGeneExp for TF |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| COAD | -3.052395701 | -0.828553394 | -2.223842308 | 1.28E-06 | 7.08E-06 |
| HNSC | -0.053180943 | 4.59747022 | -4.650651163 | 9.19E-15 | 6.15E-13 |
| BRCA | 0.881255716 | 5.386408347 | -4.505152632 | 3.43E-34 | 5.99E-33 |
| LIHC | 11.68953845 | 13.32902645 | -1.639488 | 1.46E-05 | 5.94E-05 |
| KICH | -3.169607547 | -1.573483547 | -1.596124 | 1.27E-05 | 3.93E-05 |
| THCA | -2.735069039 | -1.50213853 | -1.232930508 | 1.21E-05 | 3.88E-05 |
| STAD | -1.762002672 | 0.254628578 | -2.01663125 | 0.00181 | 0.008445415 |
| KIRP | -2.769477672 | -1.260346422 | -1.50913125 | 0.000332 | 0.001019649 |
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| TissGene-miRNA for TF |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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| TissGeneMut for TF |
| TissGeneSNV for TF |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.R132* | SKCM | 2 |
| p.K618N | BLCA | 1 |
| p.P50L | SKCM | 1 |
| p.S687L | SKCM | 1 |
| p.L681P | COAD | 1 |
| p.G547E | SKCM | 1 |
| p.R42C | KIRC | 1 |
| p.D633Y | LUAD | 1 |
| p.A62S | COAD | 1 |
| p.E394K | SKCM | 1 |
| p.R273X | COAD | 1 |
| p.D435N | SKCM | 1 |
| p.V324A | LIHC | 1 |
| p.M45I | SKCM | 1 |
| p.A539T | UCEC | 1 |
| p.Q555K | PRAD | 1 |
| p.V13I | PRAD | 1 |
| p.D109_splice | UCEC | 1 |
| p.G383R | LUAD | 1 |
| p.E337X | ESCA | 1 |
| p.G294V | BLCA | 1 |
| p.P164H | LUAD | 1 |
| p.P266S | SKCM | 1 |
| p.A605D | STAD | 1 |
| p.S317C | HNSC | 1 |
| p.K489N | LUAD | 1 |
| p.P568L | STAD | 1 |
| p.Q623K | LUAD | 1 |
| p.R663K | LUSC | 1 |
| p.R132X | COAD | 1 |
| p.R103* | UCEC | 1 |
| p.R273* | STAD | 1 |
| p.E279K | SKCM | 1 |
| p.P98L | SKCM | 1 |
| p.A455S | LUSC | 1 |
| p.G146V | LUAD | 1 |
| p.C517S | LUAD | 1 |
| p.F186L | SKCM | 1 |
| p.E501D | STAD | 1 |
| p.E672K | HNSC | 1 |
| p.A594V | COAD | 1 |
| p.K453X | READ | 1 |
| p.F321Y | LUSC | 1 |
| p.V5M | STAD | 1 |
| p.K37M | LUAD | 1 |
| p.C437F | OV | 1 |
| p.P505H | LGG | 1 |
| p.D77N | LUSC | 1 |
| p.R273Q | BLCA | 1 |
| p.L131I | HNSC | 1 |
| p.E394K | COAD | 1 |
| p.A72V | COAD | 1 |
| p.S40N | LGG | 1 |
| p.T269I | SKCM | 1 |
| p.E352K | ESCA | 1 |
| p.P482T | STAD | 1 |
| p.E394K | UCEC | 1 |
| p.C246Y | UCEC | 1 |
| p.E370K | SKCM | 1 |
| p.A145T | PAAD | 1 |
| p.R475T | LUAD | 1 |
| p.L573M | UCEC | 1 |
| p.V451A | UCS | 1 |
| p.L463M | LUAD | 1 |
| p.D296Y | UCEC | 1 |
| p.N235S | SKCM | 1 |
| p.T586S | SKCM | 1 |
| p.C656Y | HNSC | 1 |
| p.D88A | HNSC | 1 |
| p.P482L | SKCM | 1 |
| p.R273X | STAD | 1 |
| p.P307L | SKCM | 1 |
| p.E32K | SKCM | 1 |
| p.A594V | STAD | 1 |
| p.G562E | SKCM | 1 |
| p.R69G | STAD | 1 |
| p.A263S | LUAD | 1 |
| p.D395E | COAD | 1 |
| p.R132X | SKCM | 1 |
| p.E231D | READ | 1 |
| p.D584Y | THYM | 1 |
| p.K452N | UCEC | 1 |
| p.E337Q | BRCA | 1 |
| p.K399N | BLCA | 1 |
| p.R162H | UVM | 1 |
| p.T440I | UCEC | 1 |
| p.P589S | COAD | 1 |
| p.R609Q | SARC | 1 |
| p.P150L | SKCM | 1 |
| p.F498I | STAD | 1 |
| p.A398S | LUSC | 1 |
| p.E438K | THCA | 1 |
| p.L165F | SKCM | 1 |
| p.G309E | SKCM | 1 |
| p.R273Q | UCEC | 1 |
| p.K37E | UCEC | 1 |
| p.P482S | SKCM | 1 |
| p.L131F | STAD | 1 |
| p.L165V | BRCA | 1 |
| p.R132* | UCEC | 1 |
| p.F113L | UCEC | 1 |
| p.G562V | LUAD | 1 |
| p.R42C | STAD | 1 |
| p.N129K | BRCA | 1 |
| p.K452T | ESCA | 1 |
| p.C542F | ESCA | 1 |
| p.P307S | SKCM | 1 |
| p.S687L | LUSC | 1 |
| p.A218V | THYM | 1 |
| p.E75K | SKCM | 1 |
| p.W363C | OV | 1 |
| p.K61E | STAD | 1 |
| p.T654R | SKCM | 1 |
| p.R273Q | SKCM | 1 |
| p.R26T | LUAD | 1 |
| p.K331N | UCEC | 1 |
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| TissGeneCNV for TF |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| TissGeneFusions for TF |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| Chimerdb3.0 | ChiTaRs | NA | BE766500 | TF-TTL | chr3:133485171 | chr2:113280709 | |
| Chimerdb3.0 | ChiTaRs | NA | AF116645 | TF-ALB | chr3:133490909 | chr4:74279289 | |
| Chimerdb3.0 | ChiTaRs | NA | AI110837 | TF-CLDN4 | chr3:133497623 | chr7:73247009 | |
| Chimerdb3.0 | ChiTaRs | NA | AI064867 | TF-MATR3 | chr3:133474221 | chr5:138641490 | |
| Chimerdb3.0 | ChiTaRs | NA | W27988 | TF-TF | chr3:133483752 | chr3:133475763 | |
| Chimerdb3.0 | ChiTaRs | NA | BF948784 | TF-NEAT1 | chr3:133462945 | chr11:65191227 | |
| Chimerdb3.0 | ChiTaRs | NA | BF948793 | TF-NEAT1 | chr3:133462934 | chr11:65191227 | |
| Chimerdb3.0 | ChiTaRs | NA | DA338823 | ZNFX1-AS1-TF | chr20:47896939 | chr3:133465239 | |
| Chimerdb3.0 | ChiTaRs | NA | AI114794 | PICALM-TF | chr11:85700516 | chr3:133472515 | |
| Chimerdb3.0 | ChiTaRs | NA | BG769694 | LGALS1-TF | chr22:38074620 | chr3:133473543 | |
| Chimerdb3.0 | TopHat-Fusion | LUAD | TCGA-69-8255-01A | TF-ALB | Out-of-Frame | chr3:133485222 | chr4:74279261 |
| Chimerdb3.0 | TopHat-Fusion | LUAD | TCGA-69-8255-01A | TF-ALB | Out-of-Frame | chr3:133478016 | chr4:74280751 |
| Chimerdb3.0 | TopHat-Fusion | CHOL | TCGA-W5-AA2U-11A | TF-ALB | Out-of-Frame | chr3:133495926 | chr4:74280769 |
| Chimerdb3.0 | TopHat-Fusion | CHOL | TCGA-W5-AA34-11A | TF-ALB | In-Frame | chr3:133474300 | chr4:74283329 |
| Chimerdb3.0 | TopHat-Fusion | CHOL | TCGA-W5-AA30-11A | TF-ALB | In-Frame | chr3:133478117 | chr4:74283976 |
| Chimerdb3.0 | TopHat-Fusion | CHOL | TCGA-W5-AA34-11A | TF-ALB | Out-of-Frame | chr3:133495892 | chr4:74280797 |
| Chimerdb3.0 | TopHat-Fusion | CHOL | TCGA-W5-AA30-11A | TF-ALB | In-Frame | chr3:133486980 | chr4:74285331 |
| Chimerdb3.0 | TopHat-Fusion | CHOL | TCGA-W5-AA2I-11A | TF-ALB | Out-of-Frame | chr3:133495892 | chr4:74280797 |
| Chimerdb3.0 | TopHat-Fusion | CHOL | TCGA-W5-AA2R-11A | TF-ALB | Out-of-Frame | chr3:133476733 | chr4:74283999 |
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| TissGeneNet for TF |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| BRCA (tumor) | BRCA (normal) |
| TF, SMAD3, YWHAG, CTSL1, MYC, LGALS3, LAMC3, CEBPA, BCLAF1, GTF2F2, TFRC, NR2F1, IGFBP5, RYR1, IGFBP3, PRPF4, MIS12, FNBP1, IGFBP6, IGF1, CUBN (tumor) | TF, GRB2, ESR1, SAFB, IGFBP1, MYC, LGALS3, LAMC3, IL7R, FOXA1, CANX, SH3BP2, RYR1, IGFBP3, FNBP1, KRT72, TIMELESS, IGFBP6, IGF2, IGF1, CUBN (normal) |
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| COAD (tumor) | COAD (normal) |
| TF, HNF4A, GRB2, TUBB3, CTSL1, FN1, MYC, LGALS3, LAMC3, CEBPA, FOXA1, TFRC, NR2F1, IGFBP5, RYR1, IGFBP3, NFIC, FNBP1, IGF2, IGFBP2, IGFBP4 (tumor) | TF, ESR1, FN1, LGALS3, ALB, PSMA3, TTR, NR2F1, APOA1, IGFBP5, RYR1, IGFBP3, FNBP1, KRT72, TIMELESS, IGFBP6, IGF2, IGF1, LUC7L3, CUBN, IGFBP4 (normal) |
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| HNSC (tumor) | HNSC (normal) |
| TF, NCOR1, TUBB3, YWHAG, SAFB, MYC, LGALS3, BCLAF1, PSMA3, GTF2F2, FOXA1, CANX, RYR1, IGFBP3, MIS12, HFE, SERPIND1, IGFBP2, LUC7L3, TFR2, UBL5 (tumor) | TF, GRB2, TUBB3, CTSL1, UPF1, FN1, ISG15, CALR, GTF2F2, FOXA1, TFRC, TTR, NR2F1, APOA1, IGFBP5, IGF1, IGFBP2, LUC7L3, CUBN, TFR2, IGFBP4 (normal) |
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| KICH (tumor) | KICH (normal) |
| TF, GRB2, TUBB3, YWHAG, ESR1, UPF1, IGFBP1, HIF1A, MYC, LGALS3, CEBPA, ALB, CALR, FOXA1, TFRC, APOA1, RYR1, TIMELESS, HFE, SETX, GAST (tumor) | TF, HNF4A, SMAD3, NCOR1, SAFB, UPF1, MYC, PSMA3, GTF2F2, TFRC, TTR, APOA1, RYR1, IGFBP3, PRPF4, FNBP1, IGFBP6, IGF2, HFE, IGF1, UBL5 (normal) |
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| KIRC (tumor) | KIRC (normal) |
| TF, HNF4A, SMAD3, ESR1, PIAS4, IGFBP1, HIF1A, LAMC3, CEBPA, ALB, GTF2F2, TFRC, APOA1, MIS12, NFIC, IGF1, SERPIND1, IGFBP2, CUBN, GAST, IGFBP4 (tumor) | TF, NCOR1, TUBB3, FN1, ISG15, IGFBP1, CALR, FOXA1, TTR, APOA1, IGFBP5, RYR1, IGFBP3, PRPF4, IGF2, SERPIND1, IGFBP2, LUC7L3, SETX, TFR2, IGFBP4 (normal) |
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| KIRP (tumor) | KIRP (normal) |
| TF, GRB2, NCOR1, TUBB3, YWHAG, CTSL1, UPF1, FN1, IGFBP1, HIF1A, LGALS3, CEBPA, IL7R, TFRC, IGFBP5, SH3BP2, RYR1, IGF2, SETX, TFR2, IGFBP4 (tumor) | TF, NCOR1, YWHAG, SAFB, CTSL1, PIAS4, IGFBP1, ALB, FOXA1, TFRC, CANX, TTR, APOA1, IGFBP3, MIS12, IGF2, SERPIND1, IGFBP2, LUC7L3, TFR2, GAST (normal) |
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| LIHC (tumor) | LIHC (normal) |
| TF, HNF4A, GRB2, TUBB3, ESR1, CTSL1, FN1, HIF1A, MYC, CEBPA, ALB, TTR, NR2F1, APOA1, MIS12, HFE, IGF1, SERPIND1, IGFBP2, LUC7L3, TFR2 (tumor) | TF, HNF4A, SMAD3, TUBB3, YWHAG, FN1, IGFBP1, HIF1A, LGALS3, CEBPA, ALB, FOXA1, TTR, APOA1, IGFBP5, RYR1, IGFBP6, SERPIND1, IGFBP2, CUBN, TFR2 (normal) |
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| LUAD (tumor) | LUAD (normal) |
| TF, HNF4A, SMAD3, GRB2, YWHAG, SAFB, ISG15, HIF1A, LAMC3, BCLAF1, GTF2F2, IL7R, FOXA1, TTR, APOA1, MIS12, IGFBP2, LUC7L3, CUBN, SETX, IGFBP4 (tumor) | TF, HNF4A, IGFBP1, HIF1A, MYC, LGALS3, CEBPA, ALB, CALR, FOXA1, TTR, APOA1, IGFBP5, RYR1, IGFBP3, MIS12, NFIC, TIMELESS, IGFBP2, LUC7L3, GAST (normal) |
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| LUSC (tumor) | LUSC (normal) |
| TF, HNF4A, TUBB3, YWHAG, SAFB, PIAS4, ISG15, ALB, GTF2F2, IL7R, FOXA1, CANX, TTR, NR2F1, IGFBP3, TIMELESS, IGF2, IGFBP2, CUBN, TFR2, GAST (tumor) | TF, HNF4A, NCOR1, YWHAG, ESR1, IGFBP1, LGALS3, CEBPA, ALB, GTF2F2, FOXA1, TFRC, TTR, APOA1, SH3BP2, IGFBP3, TIMELESS, SERPIND1, IGFBP2, SETX, UBL5 (normal) |
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| PRAD (tumor) | PRAD (normal) |
| TF, TUBB3, CTSL1, FN1, PIAS4, HIF1A, MYC, CEBPA, ALB, PSMA3, GTF2F2, IL7R, FOXA1, CANX, TTR, NR2F1, RYR1, IGFBP3, MIS12, LUC7L3, TFR2 (tumor) | TF, SMAD3, YWHAG, ESR1, MYC, LGALS3, IL7R, FOXA1, TFRC, CANX, NR2F1, APOA1, IGFBP5, SH3BP2, RYR1, IGFBP3, FNBP1, TIMELESS, HFE, CUBN, IGFBP4 (normal) |
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| STAD (tumor) | STAD (normal) |
| TF, HNF4A, SMAD3, GRB2, TUBB3, YWHAG, ISG15, HIF1A, MYC, ALB, CALR, PSMA3, IL7R, CANX, TTR, APOA1, RYR1, IGFBP3, MIS12, HFE, GAST (tumor) | TF, TUBB3, IGFBP1, LGALS3, CEBPA, ALB, PSMA3, TFRC, TTR, NR2F1, APOA1, RYR1, FNBP1, IGFBP6, IGF2, IGF1, SERPIND1, IGFBP2, LUC7L3, CUBN, TFR2 (normal) |
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| THCA (tumor) | THCA (normal) |
| TF, GRB2, TUBB3, YWHAG, SAFB, FN1, ISG15, MYC, LGALS3, CALR, IL7R, CANX, APOA1, SH3BP2, IGFBP3, FNBP1, KRT72, TIMELESS, IGF1, LUC7L3, TFR2 (tumor) | TF, NCOR1, TUBB3, SAFB, UPF1, MYC, ALB, IL7R, CANX, TTR, APOA1, SH3BP2, NFIC, FNBP1, KRT72, IGF2, HFE, IGF1, SERPIND1, LUC7L3, TFR2 (normal) |
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| TissGeneProg for TF |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| TissGeneClin for TF |
| TissGeneDrug for TF |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| DB01370 | Aluminium | Small molecule | Approved |
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| TissGeneDisease for TF |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0002395 | Alzheimer's Disease | 15 | CTD_human,GAD,LHGDN |
| umls:C0018995 | Hemochromatosis | 5 | BeFree,GAD |
| umls:C0036341 | Schizophrenia | 4 | BeFree,GAD,LHGDN |
| umls:C0521802 | Congenital atransferrinemia | 4 | BeFree,CTD_human,MGD,ORPHANET,UNIPROT |
| umls:C0242383 | Age related macular degeneration | 3 | BeFree |
| umls:C0001973 | Alcoholic Intoxication, Chronic | 2 | CTD_human |
| umls:C0002871 | Anemia | 2 | BeFree,RGD |
| umls:C0003873 | Rheumatoid Arthritis | 2 | GAD,LHGDN |
| umls:C0006118 | Brain Neoplasms | 2 | BeFree |
| umls:C0007131 | Non-Small Cell Lung Carcinoma | 2 | BeFree |
| umls:C0007222 | Cardiovascular Diseases | 2 | GAD |
| umls:C0007786 | Brain Ischemia | 2 | GAD,LHGDN |
| umls:C0015695 | Fatty Liver | 2 | CTD_human |
| umls:C0019158 | Hepatitis | 2 | CTD_human,RGD |
| umls:C0023418 | leukemia | 2 | BeFree |
| umls:C0023893 | Liver Cirrhosis, Experimental | 2 | CTD_mouse,RGD |
| umls:C0023903 | Liver neoplasms | 2 | BeFree |
| umls:C0024667 | Animal Mammary Neoplasms | 2 | CTD_human |
| umls:C0024668 | Mammary Neoplasms, Experimental | 2 | CTD_human |
| umls:C0028754 | Obesity | 2 | CTD_human,RGD |
| umls:C0030567 | Parkinson Disease | 2 | GAD,LHGDN |
| umls:C0038454 | Cerebrovascular accident | 2 | GAD |
| umls:C0041296 | Tuberculosis | 2 | GAD,LHGDN |
| umls:C0162316 | Iron deficiency anemia | 2 | GAD |
| umls:C0376358 | Malignant neoplasm of prostate | 2 | BeFree |
| umls:C0392514 | Hereditary hemochromatosis | 2 | BeFree |
| umls:C0600139 | Prostate carcinoma | 2 | BeFree |
| umls:C2239176 | Liver carcinoma | 2 | BeFree |
| umls:C0000786 | Spontaneous abortion | 1 | GAD |
| umls:C0001349 | Acute-Phase Reaction | 1 | RGD |
| umls:C0003130 | Anoxia | 1 | GAD |
| umls:C0004096 | Asthma | 1 | GAD |
| umls:C0004352 | Autistic Disorder | 1 | CTD_human |
| umls:C0004623 | Bacterial Infections | 1 | LHGDN |
| umls:C0006142 | Malignant neoplasm of breast | 1 | BeFree |
| umls:C0007273 | Carotid Artery Diseases | 1 | GAD |
| umls:C0010674 | Cystic Fibrosis | 1 | GAD,LHGDN |
| umls:C0011570 | Mental Depression | 1 | GAD |
| umls:C0011853 | Diabetes Mellitus, Experimental | 1 | RGD |
| umls:C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 1 | LHGDN |
| umls:C0011881 | Diabetic Nephropathy | 1 | RGD |
| umls:C0013502 | Echinococcosis | 1 | CTD_human |
| umls:C0015814 | Femur Head Necrosis | 1 | GAD |
| umls:C0017636 | Glioblastoma | 1 | BeFree |
| umls:C0021368 | Inflammation | 1 | CTD_human,GAD |
| umls:C0021390 | Inflammatory Bowel Diseases | 1 | GAD |
| umls:C0021655 | Insulin Resistance | 1 | RGD |
| umls:C0022116 | Ischemia | 1 | GAD |
| umls:C0023487 | Acute Promyelocytic Leukemia | 1 | BeFree |
| umls:C0023891 | Liver Cirrhosis, Alcoholic | 1 | GAD |
| umls:C0023976 | Long QT Syndrome | 1 | GAD |
| umls:C0024117 | Chronic Obstructive Airway Disease | 1 | GAD |
| umls:C0024121 | Lung Neoplasms | 1 | LHGDN |
| umls:C0025202 | melanoma | 1 | BeFree |
| umls:C0027051 | Myocardial Infarction | 1 | GAD |
| umls:C0027626 | Neoplasm Invasiveness | 1 | CTD_human |
| umls:C0027627 | Neoplasm Metastasis | 1 | LHGDN |
| umls:C0027726 | Nephrotic Syndrome | 1 | CTD_human |
| umls:C0029445 | Bone necrosis | 1 | GAD |
| umls:C0030305 | Pancreatitis | 1 | LHGDN |
| umls:C0030524 | Paratuberculosis | 1 | CTD_human |
| umls:C0035258 | Restless Legs Syndrome | 1 | CTD_human |
| umls:C0040136 | Thyroid Neoplasm | 1 | LHGDN |
| umls:C0040336 | Tobacco Use Disorder | 1 | GAD |
| umls:C0151699 | Intracranial Hemorrhages | 1 | RGD |
| umls:C0152013 | Adenocarcinoma of lung (disorder) | 1 | CTD_human |
| umls:C0235974 | Pancreatic carcinoma | 1 | BeFree |
| umls:C0271901 | Microcytic hypochromic anemia (disorder) | 1 | CTD_human |
| umls:C0282193 | Iron Overload | 1 | CTD_human |
| umls:C0333463 | Senile Plaques | 1 | BeFree |
| umls:C0346647 | Malignant neoplasm of pancreas | 1 | BeFree |
| umls:C0483368 | Human anaplasmosis due to Anaplasma phagocytophilum | 1 | BeFree |
| umls:C0524851 | Neurodegenerative Disorders | 1 | GAD |
| umls:C0678222 | Breast Carcinoma | 1 | BeFree |
| umls:C0860207 | Drug-Induced Liver Injury | 1 | CTD_human |
| umls:C0867389 | Chronic graft-versus-host disease | 1 | BeFree |
| umls:C1621958 | Glioblastoma Multiforme | 1 | BeFree |
| umls:C2745900 | Promyelocytic leukemia | 1 | BeFree |
| umls:C2936349 | Plaque, Amyloid | 1 | BeFree |
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