 |
| |
| |
| |
| |
| |
| |
|
| TissGeneSummary for ZNF679 |
 Gene summary |
| Basic gene information | Gene symbol | ZNF679 |
| Gene name | ||
| Synonyms | ||
| Cytomap | UCSC genome browser: | |
| Type of gene | ||
| RefGenes | ||
| Description | ||
| Modification date | ||
| dbXrefs | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_ZNF679 | |
| BioGPS: 730291 | ||
| Pathway | NCI Pathway Interaction Database: ZNF679 | |
| KEGG: ZNF679 | ||
| REACTOME: ZNF679 | ||
| Pathway Commons: ZNF679 | ||
| Context | iHOP: ZNF679 | |
| ligand binding site mutation search in PubMed: ZNF679 | ||
| UCL Cancer Institute: ZNF679 | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | HPA,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
| Reference showing the relevant tissue of ZNF679 | ||
| Description by TissGene annotations | ||
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
| Top |
| TissGeneExp for ZNF679 |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
 |
| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
 |
| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
 |
| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
 |
| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| Top |
| TissGene-miRNA for ZNF679 |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
| Top |
| TissGeneMut for ZNF679 |
| TissGeneSNV for ZNF679 |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
 |
 |
| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
 |
| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.H262Y | SKCM | 3 |
| p.F25L | UCEC | 2 |
| p.R260K | UCEC | 2 |
| p.R11Q | SKCM | 2 |
| p.F363L | UCEC | 2 |
| p.S26F | SKCM | 2 |
| p.H35Y | SKCM | 2 |
| p.Y352F | COAD | 1 |
| p.R19K | SKCM | 1 |
| p.S130I | UCEC | 1 |
| p.S400I | UCEC | 1 |
| p.L33Q | LUAD | 1 |
| p.R11* | PRAD | 1 |
| p.E299K | SKCM | 1 |
| p.E378V | SKCM | 1 |
| p.R316I | COAD | 1 |
| p.S169L | SKCM | 1 |
| p.N51D | HNSC | 1 |
| p.E209K | SKCM | 1 |
| p.G404V | SKCM | 1 |
| p.E12Q | BLCA | 1 |
| p.S306N | SKCM | 1 |
| p.L123I | KIRC | 1 |
| p.T176K | ESCA | 1 |
| p.E216D | PRAD | 1 |
| p.Y212* | LUAD | 1 |
| p.E24K | SKCM | 1 |
| p.E300K | SKCM | 1 |
| p.H370Y | SKCM | 1 |
| p.L64M | BLCA | 1 |
| p.K167N | COAD | 1 |
| p.D34N | SKCM | 1 |
| p.C186R | BRCA | 1 |
| p.C354F | LUAD | 1 |
| p.Q203K | LUAD | 1 |
| p.R316I | UCEC | 1 |
| p.V83L | LUAD | 1 |
| p.K72E | UCEC | 1 |
| p.Y240C | STAD | 1 |
| p.E143D | LIHC | 1 |
| p.S253L | BLCA | 1 |
| p.E28* | LUAD | 1 |
| p.F249Y | SKCM | 1 |
| p.Q275K | LUAD | 1 |
| p.R42I | LUAD | 1 |
| p.E73K | KIRP | 1 |
| p.D121E | CESC | 1 |
| p.R173K | SKCM | 1 |
| p.Q157* | SKCM | 1 |
| p.G292V | LUAD | 1 |
| p.H262N | LUAD | 1 |
| p.R11Q | LGG | 1 |
| p.S118R | STAD | 1 |
| p.K117Q | SKCM | 1 |
| p.T84I | SKCM | 1 |
| p.S211F | SKCM | 1 |
| p.S252F | LUAD | 1 |
| p.D121G | COAD | 1 |
| p.E237Q | LUAD | 1 |
| p.K343N | COAD | 1 |
| p.R79I | SKCM | 1 |
| p.S400N | DLBC | 1 |
| p.P239T | LUAD | 1 |
| p.A58V | SKCM | 1 |
| p.T375N | UCEC | 1 |
| p.C298F | LUAD | 1 |
| p.T366N | UCEC | 1 |
| p.A58V | HNSC | 1 |
| p.C67Y | PRAD | 1 |
| p.L107V | LGG | 1 |
| p.S10T | BRCA | 1 |
| p.Q37H | PAAD | 1 |
| p.Q203* | CESC | 1 |
| p.G246D | PRAD | 1 |
| p.H234Y | SKCM | 1 |
| p.T291I | SKCM | 1 |
| p.H206D | HNSC | 1 |
| p.A2S | ESCA | 1 |
| p.C410F | ESCA | 1 |
| p.S54F | SKCM | 1 |
| p.L64M | SKCM | 1 |
| p.E73X | ESCA | 1 |
| p.E143K | SKCM | 1 |
| p.E209X | THYM | 1 |
| p.E300* | HNSC | 1 |
| p.E81D | UCEC | 1 |
| p.H86Y | BLCA | 1 |
| p.M401L | DLBC | 1 |
| p.S130I | COAD | 1 |
| p.K315N | SKCM | 1 |
| p.L27Q | LIHC | 1 |
| p.S278I | THYM | 1 |
| p.K229E | SKCM | 1 |
| p.E328K | TGCT | 1 |
| p.H346Y | SKCM | 1 |
| p.R42T | LUAD | 1 |
| p.C223S | LIHC | 1 |
| p.P323R | KIRP | 1 |
| p.K188T | UCEC | 1 |
| p.T17K | KIRP | 1 |
| p.S169L | HNSC | 1 |
| p.E73* | ESCA | 1 |
| p.A360D | PAAD | 1 |
| p.P220S | SARC | 1 |
| p.P98L | COAD | 1 |
| p.G139V | LUAD | 1 |
| p.S130R | UCEC | 1 |
| p.K355E | THCA | 1 |
| p.E29K | SKCM | 1 |
| p.S310F | SKCM | 1 |
| p.R113I | COAD | 1 |
| p.K181N | LUAD | 1 |
| p.C273Y | MESO | 1 |
| p.K78N | LUAD | 1 |
| p.C385Y | LIHC | 1 |
| p.P295S | UCEC | 1 |
| p.D386N | HNSC | 1 |
| p.F184C | LIHC | 1 |
| p.G264R | SKCM | 1 |
| p.T263A | LUAD | 1 |
| p.E47Q | LUAD | 1 |
| p.W75* | SKCM | 1 |
| p.Y212H | ACC | 1 |
| p.E356V | SKCM | 1 |
| p.G190D | SKCM | 1 |
| p.E47D | UCEC | 1 |
| p.E328K | ACC | 1 |
| p.R288I | UCEC | 1 |
| p.R113K | SKCM | 1 |
| p.D20Y | OV | 1 |
| p.K343N | LUAD | 1 |
| p.K61N | PRAD | 1 |
| p.S118C | LIHC | 1 |
| Top |
| TissGeneCNV for ZNF679 |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
 |
| Top |
| TissGeneFusions for ZNF679 |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| Chimerdb3.0 | FusionScan | LUAD | TCGA-05-4402-01A | ZNF679-VOPP1 | In-Frame | chr7:63709534 | chr7:55588823 |
| TCGAfusionPortal | PRADA | LUAD | TCGA-05-4402-01A | ZNF679-VOPP1 | In-frame | Chr7:63709534 | Chr7:55588823 |
| Top |
| TissGeneNet for ZNF679 |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| BRCA (tumor) | BRCA (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| COAD (tumor) | COAD (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| HNSC (tumor) | HNSC (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| KICH (tumor) | KICH (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| KIRC (tumor) | KIRC (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| KIRP (tumor) | KIRP (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| LIHC (tumor) | LIHC (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| LUAD (tumor) | LUAD (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| LUSC (tumor) | LUSC (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| PRAD (tumor) | PRAD (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| STAD (tumor) | STAD (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| THCA (tumor) | THCA (normal) |
| ZNF679, MDFI (tumor) | ZNF679, MDFI (normal) |
 |  |
| Top |
| TissGeneProg for ZNF679 |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
 |
| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Top |
| TissGeneClin for ZNF679 |
| TissGeneDrug for ZNF679 |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Top |
| TissGeneDisease for ZNF679 |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0040336 | Tobacco Use Disorder | 1 | GAD |
Copyright 2016-Present - The University of Texas Health Science Center at Houston (UTHealth) Web File Viewing | How to Report, Fraud, Waste and Abuse | State of Texas | Statewide Search | Texas Homeland Security | Site Policies |