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| TissGeneSummary for ZNF613 |
 Gene summary |
| Basic gene information | Gene symbol | ZNF613 |
| Gene name | zinc finger protein 613 | |
| Synonyms | - | |
| Cytomap | UCSC genome browser: 19q13.41 | |
| Type of gene | protein-coding | |
| RefGenes | NM_001031721.3, NM_024840.3, | |
| Description | - | |
| Modification date | 20141207 | |
| dbXrefs | HGNC : HGNC | |
| Ensembl : ENSG00000176024 | ||
| HPRD : 15873 | ||
| Vega : OTTHUMG00000182424 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_ZNF613 | |
| BioGPS: 79898 | ||
| Pathway | NCI Pathway Interaction Database: ZNF613 | |
| KEGG: ZNF613 | ||
| REACTOME: ZNF613 | ||
| Pathway Commons: ZNF613 | ||
| Context | iHOP: ZNF613 | |
| ligand binding site mutation search in PubMed: ZNF613 | ||
| UCL Cancer Institute: ZNF613 | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | TiGER,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Prostate | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | PRAD | |
| Reference showing the relevant tissue of ZNF613 | ||
| Description by TissGene annotations | ||
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
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| TissGeneExp for ZNF613 |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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| TissGene-miRNA for ZNF613 |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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| TissGeneMut for ZNF613 |
| TissGeneSNV for ZNF613 |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.R354H | ESCA | 2 |
| p.G256R | LGG | 1 |
| p.T197N | LUAD | 1 |
| p.I472S | PCPG | 1 |
| p.G424E | PAAD | 1 |
| p.R354H | UCEC | 1 |
| p.L562F | UCEC | 1 |
| p.G220R | LGG | 1 |
| p.T421A | UCEC | 1 |
| p.R270C | STAD | 1 |
| p.H530Y | SKCM | 1 |
| p.R354H | LGG | 1 |
| p.R384C | COAD | 1 |
| p.P65L | SARC | 1 |
| p.C293F | KIRP | 1 |
| p.R560L | BLCA | 1 |
| p.S329C | STAD | 1 |
| p.Y260C | PCPG | 1 |
| p.L32M | UCEC | 1 |
| p.N199I | STAD | 1 |
| p.H204Y | SKCM | 1 |
| p.E593K | OV | 1 |
| p.R560H | UCEC | 1 |
| p.R266W | COAD | 1 |
| p.H478D | HNSC | 1 |
| p.S287* | LUSC | 1 |
| p.R270C | SKCM | 1 |
| p.D531Y | READ | 1 |
| p.K384E | HNSC | 1 |
| p.V15A | STAD | 1 |
| p.R419* | UCEC | 1 |
| p.P65S | SARC | 1 |
| p.S438N | PAAD | 1 |
| p.R354H | PAAD | 1 |
| p.G452* | UCEC | 1 |
| p.P179S | SKCM | 1 |
| p.E208K | BLCA | 1 |
| p.R524H | COAD | 1 |
| p.A589V | UCEC | 1 |
| p.R328S | LUAD | 1 |
| p.H169Q | KIRP | 1 |
| p.S607L | SKCM | 1 |
| p.A597V | UCEC | 1 |
| p.D611N | LUSC | 1 |
| p.E257D | CESC | 1 |
| p.E593Q | HNSC | 1 |
| p.R116M | LUAD | 1 |
| p.E509* | LUAD | 1 |
| p.G508W | ESCA | 1 |
| p.E257D | UCEC | 1 |
| p.H474R | PAAD | 1 |
| p.K215N | CESC | 1 |
| p.E69K | BLCA | 1 |
| p.C615Y | UCEC | 1 |
| p.K496N | SKCM | 1 |
| p.K460N | SKCM | 1 |
| p.K398N | STAD | 1 |
| p.G156V | LUAD | 1 |
| p.N587I | LIHC | 1 |
| p.R504K | UCEC | 1 |
| p.I80M | LUAD | 1 |
| p.F437V | STAD | 1 |
| p.P121L | THYM | 1 |
| p.R330S | LUAD | 1 |
| p.P602H | LGG | 1 |
| p.E313K | CESC | 1 |
| p.M576I | UCEC | 1 |
| p.F456V | LUAD | 1 |
| p.R196Q | STAD | 1 |
| p.G63E | CESC | 1 |
| p.D561Y | BLCA | 1 |
| p.H168Y | SKCM | 1 |
| p.W271* | SKCM | 1 |
| p.H330D | LGG | 1 |
| p.R503W | UCEC | 1 |
| p.E20* | LUSC | 1 |
| p.E264K | CESC | 1 |
| p.G317E | LGG | 1 |
| p.C377F | CHOL | 1 |
| p.L24F | THCA | 1 |
| p.E432K | BRCA | 1 |
| p.H523R | HNSC | 1 |
| p.C377F | BRCA | 1 |
| p.R392Q | UCEC | 1 |
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| TissGeneCNV for ZNF613 |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| TissGeneFusions for ZNF613 |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| TCGAfusionPortal | PRADA | BRCA | TCGA-AR-A0U3-01A | ZNF613-CYP2A6 | 5UTR-CDS | Chr19:52433149 | Chr19:41354668 |
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| TissGeneNet for ZNF613 |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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| TissGeneProg for ZNF613 |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| TissGeneClin for ZNF613 |
| TissGeneDrug for ZNF613 |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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| TissGeneDisease for ZNF613 |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
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