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TissGeneSummary for GSG1 |
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Basic gene information | Gene symbol | GSG1 |
Gene name | germ cell associated 1 | |
Synonyms | - | |
Cytomap | UCSC genome browser: 12p13.1 | |
Type of gene | protein-coding | |
RefGenes | NM_001080554.2, NM_001080555.2,NM_001206842.1,NM_001206843.1,NM_001206845.1, NM_031289.3,NM_153823.3, | |
Description | germ cell-specific gene 1 protein | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000111305 | ||
HPRD : 11015 | ||
Vega : OTTHUMG00000150148 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_GSG1 | |
BioGPS: 83445 | ||
Pathway | NCI Pathway Interaction Database: GSG1 | |
KEGG: GSG1 | ||
REACTOME: GSG1 | ||
Pathway Commons: GSG1 | ||
Context | iHOP: GSG1 | |
ligand binding site mutation search in PubMed: GSG1 | ||
UCL Cancer Institute: GSG1 | ||
Assigned class in TissGDB* | B | |
Included tissue-specific gene expression resources | HPA,TiGER,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | TestisEye | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCTUVM | |
Reference showing the relevant tissue of GSG1 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
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GO ID | GO term | PubMed ID |
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TissGeneExp for GSG1 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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![]() (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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![]() (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
KICH | -0.021542613 | 2.898257387 | -2.9198 | 7.71E-10 | 4.97E-09 |
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TissGene-miRNA for GSG1 |
![]() (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for GSG1 |
TissGeneSNV for GSG1 |
![]() Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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![]() (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.E103K | SKCM | 2 |
p.Q318K | STAD | 1 |
p.E64K | BLCA | 1 |
p.Q78K | LUAD | 1 |
p.F240L | BLCA | 1 |
p.F276L | STAD | 1 |
p.L232V | STAD | 1 |
p.P187S | SKCM | 1 |
p.R160K | STAD | 1 |
p.D3H | BLCA | 1 |
p.H184Y | BLCA | 1 |
p.R264W | SKCM | 1 |
p.P286H | LUAD | 1 |
p.R100W | KIRP | 1 |
p.L17I | HNSC | 1 |
p.D331N | STAD | 1 |
p.G303S | COAD | 1 |
p.D270N | PAAD | 1 |
p.P288L | UCEC | 1 |
p.Q306K | SARC | 1 |
p.L148Q | COAD | 1 |
p.R243C | THYM | 1 |
p.H184Y | LUAD | 1 |
p.S7L | BLCA | 1 |
p.A260V | UCEC | 1 |
p.D234N | PAAD | 1 |
p.E51K | BLCA | 1 |
p.V274L | LUAD | 1 |
p.P61S | CESC | 1 |
p.D151N | SKCM | 1 |
p.Q172X | COAD | 1 |
p.E110K | SKCM | 1 |
p.A211T | PRAD | 1 |
p.S5Y | THYM | 1 |
p.E102K | HNSC | 1 |
p.R87W | KIRP | 1 |
p.W252L | HNSC | 1 |
p.E115K | HNSC | 1 |
p.F341L | UCEC | 1 |
p.R180X | STAD | 1 |
p.T265I | LIHC | 1 |
p.V11A | UCEC | 1 |
p.C101F | SKCM | 1 |
p.F23V | UCEC | 1 |
p.E131K | SKCM | 1 |
p.Q172K | ESCA | 1 |
p.S89P | MESO | 1 |
p.S172F | SKCM | 1 |
p.K249T | LGG | 1 |
p.G183R | SKCM | 1 |
p.D3N | STAD | 1 |
p.D3Y | UCEC | 1 |
p.G147R | SKCM | 1 |
p.S105R | STAD | 1 |
p.R91W | COAD | 1 |
p.L6I | LUAD | 1 |
p.M184I | SKCM | 1 |
p.F276L | BLCA | 1 |
p.W216L | HNSC | 1 |
p.G201V | COAD | 1 |
p.E167K | SKCM | 1 |
p.S7P | BLCA | 1 |
p.V63L | HNSC | 1 |
p.E275* | UCEC | 1 |
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TissGeneCNV for GSG1 |
![]() (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for GSG1 |
![]() (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | ChiTaRs | NA | AI016246 | LOC440934-GSG1 | chr2:223186375 | chr12:13241798 |
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TissGeneNet for GSG1 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for GSG1 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for GSG1 |
TissGeneDrug for GSG1 |
![]() (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for GSG1 |
![]() (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0040336 | Tobacco Use Disorder | 1 | GAD |