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TissGeneSummary for RTP3 |
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Basic gene information | Gene symbol | RTP3 |
Gene name | receptor (chemosensory) transporter protein 3 | |
Synonyms | LTM1|TMEM7|Z3CXXC3 | |
Cytomap | UCSC genome browser: 3p21.3 | |
Type of gene | protein-coding | |
RefGenes | NM_031440.1, | |
Description | receptor transporter protein 3receptor transporting protein 3receptor-transporting protein 3transmembrane protein 7zinc finger, 3CxxC-type 3 | |
Modification date | 20141207 | |
dbXrefs | MIM : 607181 | |
HGNC : HGNC | ||
HPRD : 06214 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_RTP3 | |
BioGPS: 83597 | ||
Pathway | NCI Pathway Interaction Database: RTP3 | |
KEGG: RTP3 | ||
REACTOME: RTP3 | ||
Pathway Commons: RTP3 | ||
Context | iHOP: RTP3 | |
ligand binding site mutation search in PubMed: RTP3 | ||
UCL Cancer Institute: RTP3 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Liver | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | LIHC | |
Reference showing the relevant tissue of RTP3 | ||
Description by TissGene annotations | Significant down-regulated DEG TissgsKTS CNV lost TissGeneKTS |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
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GO ID | GO term | PubMed ID | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste | 16720576 | GO:0006612 | protein targeting to membrane | 16720576 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste | 16720576 | GO:0006612 | protein targeting to membrane | 16720576 |
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TissGeneExp for RTP3 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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![]() (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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![]() (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
HNSC | 0.893808384 | -0.753638128 | 1.647446512 | 1.30E-05 | 7.17E-05 |
KIRP | -0.969600701 | 0.365393049 | -1.33499375 | 3.98E-06 | 1.78E-05 |
LIHC | 7.073263174 | 8.564525174 | -1.491262 | 0.00153 | 0.004021456 |
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TissGene-miRNA for RTP3 |
![]() (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for RTP3 |
TissGeneSNV for RTP3 |
![]() Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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![]() (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.R121Q | SKCM | 2 |
p.R130K | HNSC | 1 |
p.I143M | LUSC | 1 |
p.L70P | THYM | 1 |
p.A51D | LUAD | 1 |
p.P21L | LUAD | 1 |
p.L68M | UCEC | 1 |
p.G129E | SKCM | 1 |
p.P177T | PRAD | 1 |
p.F214L | HNSC | 1 |
p.V224M | LGG | 1 |
p.K124N | BLCA | 1 |
p.L38M | UCEC | 1 |
p.E102K | SKCM | 1 |
p.R17W | STAD | 1 |
p.P21L | UCEC | 1 |
p.M16T | LUAD | 1 |
p.M86I | SKCM | 1 |
p.P138S | SKCM | 1 |
p.P177Q | OV | 1 |
p.Q167K | LUSC | 1 |
p.W8* | SKCM | 1 |
p.E6* | BLCA | 1 |
p.L133S | ESCA | 1 |
p.Q13H | STAD | 1 |
p.Q13K | HNSC | 1 |
p.C203Y | BLCA | 1 |
p.S112* | BLCA | 1 |
p.I207V | PRAD | 1 |
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TissGeneCNV for RTP3 |
![]() (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for RTP3 |
![]() (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for RTP3 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for RTP3 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for RTP3 |
TissGeneDrug for RTP3 |
![]() (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for RTP3 |
![]() (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0023903 | Liver neoplasms | 1 | CTD_human |
umls:C2239176 | Liver carcinoma | 1 | BeFree,CTD_human,LHGDN |