TissGDB
Tissglogo

Home

Download

 Statistics

 Landscape

Help

Contact
Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory

bullet point

TissGeneSummary

bullet point

TissGeneExp

bullet point

TissGene-miRNA

bullet point

TissGeneMut: TissGeneSNV, TissGeneCNV, and TissGeneFusions

bullet point

TissGeneNet

bullet point

TissGeneProg

bullet point

TissGeneClin: TissGeneDrug and TissGeneDisease

TissGeneSummary for CAT
check button Gene summary
Basic gene informationGene symbolCAT
Gene namecatalase
Synonyms-
CytomapUCSC genome browser: 11p13
Type of geneprotein-coding
RefGenesNM_001752.3,
Description-
Modification date20141207
dbXrefs MIM : 115500
HGNC : HGNC
Ensembl : ENSG00000121691
HPRD : 00282
Vega : OTTHUMG00000044353
ProteinUniProt:
go to UniProt's Cross Reference DB Table
ExpressionCleanEX: HS_CAT
BioGPS: 847
PathwayNCI Pathway Interaction Database: CAT
KEGG: CAT
REACTOME: CAT
Pathway Commons: CAT
ContextiHOP: CAT
ligand binding site mutation search in PubMed: CAT
UCL Cancer Institute: CAT
Assigned class in TissGDB*C
Included tissue-specific gene expression resourcesTiGER,GTEx
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx)Bone marrowLiver
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA)LAMLLIHC
Reference showing the relevant tissue of CAT
Description by TissGene annotationsTissgsLTS
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C.

check button Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez
GO IDGO termPubMed ID
GO:0001649osteoblast differentiation16210410
GO:0042744hydrogen peroxide catabolic process18379038
GO:0051262protein tetramerization10656833
GO:0051289protein homotetramerization21976670
GO:0001649osteoblast differentiation16210410
GO:0042744hydrogen peroxide catabolic process18379038
GO:0051262protein tetramerization10656833
GO:0051289protein homotetramerization21976670


Top
TissGeneExp for CAT

check button Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
gene exp


check button Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01)
gene isoform exp


check button Gene expressions across normal tissues of GTEx data
(GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct)
- Here, we shows the matched tissue types only among our 28 cancer types.
normal gene exp


check button Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
DEG exp

- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05)
Cancer typeMean(exp) in tumorMean(exp) in matched normalLog2FCP-val.FDR
LUAD0.0607519542.095760574-2.0350086218.11E-309.10E-28
LIHC2.3690767813.837006781-1.467932.68E-136.20E-12
KIRC1.175673172.314670392-1.1389972225.49E-245.97E-23
BRCA-0.0103462011.719769588-1.7301157891.70E-384.46E-37
KIRP0.8061374062.156615531-1.3504781251.57E-101.71E-09
LUSC-0.3533492971.953852663-2.3072019612.48E-301.12E-28


Top
TissGene-miRNA for CAT

check button Significantly anti-correlated miRNAs of TissGene across 28 cancer types
(Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016)
(TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21)
(TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16)
(Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25))
Cancer typemiRNA idmiRNA accessionP-val.Coeff.# samples


Top
TissGeneMut for CAT
TissGeneSNV for CAT

check button nsSNV counts per each loci.
Different colors of circles represent different cancer types. Circle size denotes number of samples.
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)
* Click on the image to enlarge it in a new window.
SNV lollipop
bullet point


check button Somatic nucleotide variants of TissGene across 28 cancer types
(X-axis: cancer type and Y-axis: % of mutated samples)
The numbers in parentheses are numbers of samples with mutation (nsSNVs).
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)
SNV distribution

- nsSNVs sorted by frequency.
AAchangeCancer type# samples
p.N369SBLCA1
p.G227RBLCA1
p.A520VBRCA1
p.P179LUCEC1
p.Q442RSTAD1
p.A520VCESC1
p.P151LSKCM1
p.R112WSKCM1
p.E101QBLCA1
p.G32DLGG1
p.D202AKIRP1
p.P151SSKCM1
p.R72THNSC1
p.I343VLUAD1
p.A250VCOAD1
p.I493MBLCA1
p.P49HSTAD1
p.E344KSKCM1
p.E67VSKCM1
p.F334VSTAD1
p.G516EUCEC1
p.V87DSTAD1
p.K177EPRAD1
p.T441SSKCM1
p.R363HUCEC1
p.D498ESKCM1
p.R47HBLCA1
p.E503KLUAD1
p.Q352HLUAD1
p.H235YSKCM1
p.E86QBLCA1
p.D335NUCEC1
p.P296SSKCM1
p.P206SSKCM1
p.I463TBLCA1
p.R354HCOAD1
p.L245FSKCM1
p.A357TPAAD1
p.E330KCESC1
p.Q288RSTAD1
p.G465RBLCA1
p.V450MUVM1
p.P172SSKCM1
p.V146IHNSC1
p.R430WHNSC1
p.L265FHNSC1
p.P296LSARC1
p.R203QLGG1


Top
TissGeneCNV for CAT

check button Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples)
(TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16)
CNV


Top
TissGeneFusions for CAT

check button Fusion genes including TissGene
(ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01)
DatabaseSrcCancer typeSampleFusion geneORF5'-gene BP3'-gene BP
Chimerdb3.0ChiTaRsNABI024383CAT-MARK3chr11:34480259chr14:103958203
Chimerdb3.0ChiTaRsNABI028162CAT-MARK3chr11:34480266chr14:103958203
Chimerdb3.0ChiTaRsNABI022068MARK3-CATchr14:103958302chr11:34480167
Chimerdb3.0FusionScanBRCATCGA-AC-A2BK-01ACAPRIN1-CATIn-Framechr11:34093534chr11:34470738
TCGAfusionPortalPRADABRCATCGA-AN-A0AL-01APDHX-CATOut-of-frameChr11:34982065Chr11:34492505
TCGAfusionPortalPRADABRCATCGA-B6-A0I1-01AELF5-CATIn-frameChr11:34515026Chr11:34485652
TCGAfusionPortalPRADABRCATCGA-E9-A1RB-01APDHX-CATIn-frameChr11:34999729Chr11:34477558
TCGAfusionPortalPRADABRCATCGA-EW-A1P7-01ATLK1-CATIn-frameChr2:171974249Chr11:34470739
TCGAfusionPortalPRADALUADTCGA-55-8510-01AHIPK3-CATIn-frameChr11:33373811Chr11:34470739
TCGAfusionPortalPRADAOVTCGA-13-0905-01BCAT-CD3DOut-of-frameChr11:34460626Chr11:118210209


Top
TissGeneNet for CAT

check button Co-expressed gene networks based on protein-protein interaction data (CePIN)
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(PINA2 ppi data)
BRCA (tumor)BRCA (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
COAD (tumor)COAD (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
HNSC (tumor)HNSC (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
KICH (tumor)KICH (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
KIRC (tumor)KIRC (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
KIRP (tumor)KIRP (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
LIHC (tumor)LIHC (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
LUAD (tumor)LUAD (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
LUSC (tumor)LUSC (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
PRAD (tumor)PRAD (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
STAD (tumor)STAD (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point
THCA (tumor)THCA (normal)
CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (tumor)CAT, UBC, SP1, GRB2, NFYA, PTPN11, EGR1, APP, ABL1, KEAP1, NFYB, SUMO4, NFYC, GCDH, TLR10, USP53, PEX5, ABL2, TYSND1 (normal)
bullet pointbullet point


Top
TissGeneProg for CAT

check button Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image to enlarge it in a new window.
survival 1

check button Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.
survival 2

check button Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.
survival 3

check button Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.
survival 4

Top
TissGeneClin for CAT
TissGeneDrug for CAT

check button Drug information targeting TissGene
(DrugBank Version 5.0.6, 2017-04-01)
DrugBank IDDrug nameDrug activityDrug typeDrug status
DB01213FomepizoleInhibitorSmall moleculeApproved|Vet_approved


Top
TissGeneDisease for CAT

check button Disease information associated with TissGene
(DisGeNet, 2016-06-01)
Disease IDDisease name# pubmedsSource
umls:C0006142Malignant neoplasm of breast27BeFree,GAD
umls:C2239176Liver carcinoma26BeFree,GAD
umls:C0019693HIV Infections25BeFree
umls:C0678222Breast Carcinoma24BeFree
umls:C0042900Vitiligo22BeFree,GAD
umls:C1847835VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)21BeFree
umls:C0023903Liver neoplasms20BeFree,GAD
umls:C0020538Hypertensive disease18BeFree,CTD_human,GAD,LHGDN,RGD
umls:C0011860Diabetes Mellitus, Non-Insulin-Dependent16BeFree,CTD_human,GAD
umls:C0011849Diabetes Mellitus12BeFree,CTD_human,GAD,LHGDN
umls:C0268419Acatalasia12BeFree,CLINVAR,CTD_human,ORPHANET
umls:C0003076Aniridia11BeFree
umls:C0004096Asthma11BeFree,CTD_human,GAD,LHGDN
umls:C0041296Tuberculosis11BeFree
umls:C0011854Diabetes Mellitus, Insulin-Dependent10BeFree,CTD_human,GAD
umls:C0027708Nephroblastoma10BeFree
umls:C0043346Xeroderma Pigmentosum10BeFree
umls:C1458155Mammary Neoplasms10BeFree,CTD_human,LHGDN
umls:C0011881Diabetic Nephropathy8BeFree,GAD,RGD
umls:C0600139Prostate carcinoma8BeFree
umls:C0027627Neoplasm Metastasis7BeFree,CTD_human
umls:C0027819Neuroblastoma7BeFree
umls:C0376358Malignant neoplasm of prostate7BeFree
umls:C0700095Central neuroblastoma7BeFree
umls:C0003873Rheumatoid Arthritis6BeFree,CTD_human,GAD,LHGDN
umls:C0007137Squamous cell carcinoma6BeFree,GAD,LHGDN
umls:C0018203Chronic granulomatous disease6BeFree
umls:C0022116Ischemia6BeFree
umls:C0024141Lupus Erythematosus, Systemic6BeFree,GAD,LHGDN
umls:C0035126Reperfusion Injury6CTD_human,RGD
umls:C0242379Malignant neoplasm of lung6BeFree
umls:C0684249Carcinoma of lung6BeFree
umls:C0004153Atherosclerosis5BeFree,GAD
umls:C0022661Kidney Failure, Chronic5BeFree,CTD_human,GAD,RGD
umls:C0024115Lung diseases5BeFree,LHGDN,RGD
umls:C0024117Chronic Obstructive Airway Disease5BeFree,GAD,LHGDN
umls:C0043459Zellweger Syndrome5BeFree
umls:C0003850Arteriosclerosis4BeFree
umls:C0005283beta Thalassemia4BeFree
umls:C0007621Neoplastic Cell Transformation4CTD_human
umls:C0008626Congenital chromosomal disease4BeFree
umls:C0011847Diabetes4BeFree
umls:C0011853Diabetes Mellitus, Experimental4CTD_human,RGD
umls:C0012860DNA Damage4GAD
umls:C0013080Down Syndrome4BeFree
umls:C0013949Embryopathies4BeFree
umls:C0022658Kidney Diseases4BeFree,GAD
umls:C0025202melanoma4BeFree,GAD
umls:C0038220Status Epilepticus4CTD_human
umls:C0206624Hepatoblastoma4BeFree
umls:C0282527Infantile Refsum Disease (disorder)4BeFree
umls:C0302592Cervix carcinoma4BeFree
umls:C0752120Spinocerebellar Ataxia Type 14BeFree
umls:C2931868Catalase deficiency4BeFree
umls:C0000833Abscess3BeFree
umls:C0001418Adenocarcinoma3BeFree,LHGDN
umls:C0001973Alcoholic Intoxication, Chronic3BeFree
umls:C0002736Amyotrophic Lateral Sclerosis3BeFree
umls:C0007131Non-Small Cell Lung Carcinoma3BeFree,CTD_human
umls:C0007222Cardiovascular Diseases3BeFree,GAD
umls:C0015695Fatty Liver3BeFree,CTD_human,RGD
umls:C0021400Influenza3BeFree
umls:C0032002Pituitary Diseases3BeFree
umls:C0033860Psoriasis3BeFree,CTD_human,LHGDN
umls:C0036572Seizures3CTD_human
umls:C0085207Gestational Diabetes3BeFree
umls:C0085580Essential Hypertension3BeFree
umls:C0206661Gonadoblastoma3BeFree
umls:C0242656Disease Progression3CTD_human
umls:C0343401MRSA - Methicillin resistant Staphylococcus aureus infection3BeFree
umls:C0375023Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site3BeFree
umls:C0752048Hypocatalasemia3BeFree
umls:C0878544Cardiomyopathies3BeFree,CTD_human
umls:C0000768Congenital Abnormality2BeFree
umls:C0001925Albuminuria2GAD
umls:C0002395Alzheimer's Disease2BeFree,GAD
umls:C0003949Asbestosis2BeFree,GAD
umls:C0004135Ataxia Telangiectasia2BeFree
umls:C0004610Bacteremia2BeFree
umls:C0006118Brain Neoplasms2GAD,LHGDN
umls:C0007102Malignant tumor of colon2BeFree
umls:C0007114Malignant neoplasm of skin2BeFree
umls:C0007786Brain Ischemia2CTD_human,RGD
umls:C0007847Malignant tumor of cervix2BeFree
umls:C0008497Choriocarcinoma2BeFree
umls:C0009207Cockayne Syndrome2BeFree
umls:C0009319Colitis2BeFree,RGD
umls:C0009375Colonic Neoplasms2BeFree
umls:C0010068Coronary heart disease2BeFree,GAD
umls:C0011875Diabetic Angiopathies2BeFree,GAD
umls:C0011882Diabetic Neuropathies2BeFree,CTD_human,GAD
umls:C0011884Diabetic Retinopathy2BeFree,RGD
umls:C0014072Experimental Autoimmune Encephalomyelitis2BeFree
umls:C0017152Gastritis2BeFree
umls:C0017160Gastroenteritis2BeFree
umls:C0018081Gonorrhea2BeFree
umls:C0018790Cardiac Arrest2BeFree
umls:C0018801Heart failure2BeFree,CTD_human
umls:C0018802Congestive heart failure2BeFree
umls:C0020429Hyperalgesia2RGD
umls:C0020550Hyperthyroidism2CTD_human,RGD
umls:C0021368Inflammation2GAD,LHGDN
umls:C0023493Adult T-Cell Lymphoma/Leukemia2BeFree
umls:C0023891Liver Cirrhosis, Alcoholic2BeFree,CTD_human,GAD
umls:C0024299Lymphoma2BeFree
umls:C0024305Lymphoma, Non-Hodgkin2BeFree,GAD
umls:C0025362Mental Retardation2BeFree
umls:C0025517Metabolic Diseases2BeFree
umls:C0026946Mycoses2BeFree
umls:C0027051Myocardial Infarction2CTD_human,RGD
umls:C0027055Myocardial Reperfusion Injury2CTD_human,RGD
umls:C0027540Necrosis2CTD_human
umls:C0027626Neoplasm Invasiveness2CTD_human
umls:C0028754Obesity2BeFree
umls:C0029134Optic Neuritis2BeFree
umls:C0029463Osteosarcoma2BeFree
umls:C0029925Ovarian Carcinoma2BeFree
umls:C0036202Sarcoidosis2BeFree
umls:C0038358Gastric ulcer2CTD_human,RGD
umls:C0042373Vascular Diseases2BeFree
umls:C0085576Iron-Refractory Iron Deficiency Anemia2BeFree
umls:C0149925Small cell carcinoma of lung2BeFree
umls:C0162429Malnutrition2BeFree,GAD
umls:C0238461Anaplastic thyroid carcinoma2BeFree
umls:C0282525Adrenoleukodystrophy, Neonatal2BeFree
umls:C0345967Malignant mesothelioma2BeFree
umls:C0476089Endometrial Carcinoma2BeFree
umls:C0497406Overweight2BeFree
umls:C0585442Osteosarcoma of bone2BeFree
umls:C0699790Colon Carcinoma2BeFree
umls:C0856169Endothelial dysfunction2BeFree
umls:C0878521Beta thalassemia trait2BeFree
umls:C1140680Malignant neoplasm of ovary2BeFree
umls:C1168401Squamous cell carcinoma of the head and neck2BeFree
umls:C1269683Major Depressive Disorder2BeFree,CTD_human
umls:C1527249Colorectal Cancer2BeFree,GAD
umls:C1561643Chronic Kidney Diseases2BeFree
umls:C1862941Amyotrophic Lateral Sclerosis, Sporadic2BeFree
umls:C1956346Coronary Artery Disease2BeFree
umls:C2936847Acatalasemia Japanese type2BeFree,CLINVAR
umls:C0001261Actinomycosis1BeFree
umls:C0001339Acute pancreatitis1BeFree
umls:C0001430Adenoma1BeFree
umls:C0002894Refractory anaemia with excess blasts1BeFree
umls:C0003469Anxiety Disorders1BeFree
umls:C0003493Aortic Diseases1CTD_human
umls:C0004030Aspergillosis1BeFree
umls:C0004031Aspergillosis, Allergic Bronchopulmonary1BeFree
umls:C0004045Asphyxia Neonatorum1CTD_human
umls:C0004352Autistic Disorder1CTD_human
umls:C0004626Pneumonia, Bacterial1RGD
umls:C0004763Barrett Esophagus1BeFree
umls:C0004943Behcet Syndrome1CTD_human
umls:C0005586Bipolar Disorder1BeFree
umls:C0005684Malignant neoplasm of urinary bladder1GAD
umls:C0006287Bronchopulmonary Dysplasia1RGD
umls:C0007115Malignant neoplasm of thyroid1BeFree
umls:C0007117Basal cell carcinoma1GAD
umls:C0008370Cholestasis1RGD
umls:C0008384Cholesterol Ester Storage Disease1BeFree
umls:C0009324Ulcerative Colitis1BeFree
umls:C0010495Cutis Laxa1BeFree
umls:C0010674Cystic Fibrosis1BeFree
umls:C0011389Dental Plaque1BeFree
umls:C0011603Dermatitis1BeFree
umls:C0013386Dyskinesia, Drug-Induced1CTD_human
umls:C0013604Edema1CTD_human
umls:C0014009Empyema1BeFree
umls:C0014175Endometriosis1LHGDN
umls:C0015625Fanconi Anemia1BeFree
umls:C0016667Fragile X Syndrome1BeFree
umls:C0016719Friedreich Ataxia1BeFree
umls:C0017638Glioma1CTD_human
umls:C0018784Sensorineural Hearing Loss (disorder)1RGD
umls:C0019158Hepatitis1CTD_human
umls:C0019163Hepatitis B1BeFree
umls:C0019189Hepatitis, Chronic1CTD_human
umls:C0019202Hepatolenticular Degeneration1BeFree
umls:C0019348Herpes Simplex Infections1BeFree
umls:C0020179Huntington Disease1RGD
umls:C0020452Hyperemia1CTD_human
umls:C0020456Hyperglycemia1BeFree
umls:C0020649Hypotension1CTD_human
umls:C0021364Male infertility1BeFree
umls:C0021655Insulin Resistance1GAD
umls:C0021670insulinoma1BeFree
umls:C0022578Keratoconus1BeFree
umls:C0022593Keratosis1CTD_human
umls:C0022610Kernicterus1BeFree
umls:C0022650Kidney Calculi1CTD_human
umls:C0022660Kidney Failure, Acute1BeFree
umls:C0023418leukemia1GAD
umls:C0023524Leukoencephalopathy, Progressive Multifocal1BeFree
umls:C0023860Listeriosis1BeFree
umls:C0023890Liver Cirrhosis1BeFree
umls:C0024530Malaria1BeFree
umls:C0024623Malignant neoplasm of stomach1BeFree
umls:C0024796Marfan Syndrome1CTD_human
umls:C0025500Mesothelioma1CTD_human
umls:C0025958Microcephaly1BeFree
umls:C0026499Monosomy1BeFree
umls:C0026636Mouth Diseases1BeFree
umls:C0026640Mouth Neoplasms1GAD
umls:C0026769Multiple Sclerosis1LHGDN
umls:C0028797Occupational Diseases1GAD
umls:C0029408Degenerative polyarthritis1BeFree
umls:C0029445Bone necrosis1GAD
umls:C0029456Osteoporosis1BeFree
umls:C0029458Osteoporosis, Postmenopausal1CTD_human
umls:C0029882Otitis Media1RGD
umls:C0030297Pancreatic Neoplasm1GAD
umls:C0030305Pancreatitis1GAD
umls:C0030567Parkinson Disease1BeFree
umls:C0031039Pericardial effusion1BeFree
umls:C0031046Pericarditis1BeFree
umls:C0031485Phenylketonurias1RGD
umls:C0031511Pheochromocytoma1BeFree
umls:C0032019Pituitary Neoplasms1BeFree
umls:C0032131Plasmacytoma1BeFree
umls:C0032927Precancerous Conditions1BeFree,CTD_human
umls:C0033626Protein Deficiency1CTD_human
umls:C0033847Pseudoxanthoma Elasticum1GAD
umls:C0034063Pulmonary Edema1CTD_human
umls:C0034065Pulmonary Embolism1CTD_human
umls:C0034067Pulmonary Emphysema1BeFree
umls:C0034150Purpura1LHGDN
umls:C0034960Refsum Disease1BeFree
umls:C0035242Respiratory Tract Diseases1GAD
umls:C0035309Retinal Diseases1RGD
umls:C0037054Sickle Cell Trait1BeFree
umls:C0037286Skin Neoplasms1GAD
umls:C0038362Stomatitis1RGD
umls:C0038454Cerebrovascular accident1BeFree
umls:C0038814Sunburn1GAD
umls:C0038826Superinfection1BeFree
umls:C0041408Turner Syndrome1CTD_human
umls:C0041696Unipolar Depression1BeFree
umls:C0041956Ureteral obstruction1RGD
umls:C0042109Urticaria1LHGDN
umls:C0043119Werner Syndrome1BeFree
umls:C0079474Hallopeau-Siemens Disease1BeFree
umls:C0079744Diffuse Large B-Cell Lymphoma1CTD_human
umls:C0085179Eosinophilia-Myalgia Syndrome1BeFree
umls:C0085762Alcohol abuse1GAD
umls:C0086543Cataract1RGD
umls:C0087012Ataxia, Spinocerebellar1BeFree
umls:C0149521Pancreatitis, Chronic1BeFree,GAD
umls:C0149721Left Ventricular Hypertrophy1RGD
umls:C0149940Sciatic Neuropathy1RGD
umls:C0151526Premature Birth1CTD_human
umls:C0153381Malignant neoplasm of mouth1BeFree
umls:C0162532Variegate Porphyria1BeFree
umls:C0162835Hypopigmentation disorder1BeFree
umls:C0162872Aortic Aneurysm, Thoracic1BeFree
umls:C0206042Fatal Familial Insomnia1BeFree
umls:C0206146Myocardial Stunning1BeFree
umls:C0206659Embryonal Carcinoma1BeFree
umls:C0206664Teratocarcinoma1BeFree
umls:C0206682Follicular thyroid carcinoma1BeFree
umls:C0220641Lip and Oral Cavity Carcinoma1BeFree
umls:C0220810Congenital defects1BeFree
umls:C0221757alpha 1-Antitrypsin Deficiency1BeFree
umls:C0234133Extrapyramidal sign1BeFree
umls:C0235032Neurotoxicity Syndromes1RGD
umls:C0235946Cerebral atrophy1BeFree
umls:C0235974Pancreatic carcinoma1BeFree
umls:C0236969Substance-Related Disorders1GAD
umls:C0238462Medullary carcinoma of thyroid1BeFree
umls:C0238463Papillary thyroid carcinoma1BeFree
umls:C0242339Dyslipidemias1GAD
umls:C0242383Age related macular degeneration1GAD
umls:C0242488Acute Lung Injury1CTD_human
umls:C0243026Sepsis1RGD
umls:C0266929Chronic Periodontitis1BeFree
umls:C0268537Pipecolic acidemia1BeFree
umls:C0270814Spastic syndrome1BeFree
umls:C0271650Impaired glucose tolerance1GAD
umls:C0276651Aspergilloma1BeFree
umls:C0278996Cancer of Head and Neck1GAD
umls:C0281361Adenocarcinoma of pancreas1BeFree
umls:C0333295Acute ulcer1BeFree
umls:C0338656Impaired cognition1BeFree
umls:C0342257Complications of Diabetes Mellitus1GAD
umls:C0349231Phobic anxiety disorder1CTD_human
umls:C0362046Prediabetes syndrome1BeFree
umls:C0374997Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site1BeFree
umls:C0376628Chromosome Breakage1CTD_human
umls:C0403447Chronic Kidney Insufficiency1BeFree
umls:C0428796Senile sclerosis of aortic cusp1BeFree
umls:C0520947Clumsiness - motor delay1BeFree
umls:C0524620Metabolic Syndrome X1BeFree
umls:C0524851Neurodegenerative Disorders1BeFree
umls:C0524909Hepatitis B, Chronic1BeFree
umls:C0549473Thyroid carcinoma1BeFree
umls:C0600260Lung Diseases, Obstructive1BeFree
umls:C0600327Toxic Shock Syndrome1BeFree
umls:C0677886Epithelial ovarian cancer1BeFree
umls:C0699791Stomach Carcinoma1BeFree
umls:C0741260asthma adult onset1BeFree
umls:C0746604mitral valve endocarditis1BeFree
umls:C0812413Malignant Pleural Mesothelioma1BeFree
umls:C0850666Helicobacter pylori infection1BeFree
umls:C0853662Oestrogen deficiency1BeFree
umls:C0860207Drug-Induced Liver Injury1CTD_human
umls:C0870082Hyperkeratosis1BeFree,GAD
umls:C0872054latent infection1BeFree
umls:C0993582Arthritis, Experimental1CTD_human
umls:C1096293Macroangiopathy1BeFree
umls:C1171363Renoprival hypertension1RGD
umls:C1176475Ductal Carcinoma1BeFree
umls:C1258104Diffuse Scleroderma1BeFree
umls:C1263758Female genital tract infection1BeFree
umls:C1275685Avellino corneal dystrophy1BeFree
umls:C1304470Generalized vitiligo1BeFree
umls:C1334177Infiltrating Cervical Carcinoma1BeFree
umls:C1377913Pleural Mesothelioma1BeFree
umls:C1455780Aortic valve sclerosis1BeFree
umls:C1456865Ureteral Calculi1CTD_human
umls:C1519670Tumor Angiogenesis1BeFree
umls:C1520166Xenograft Model1BeFree
umls:C1527349Ductal Breast Carcinoma1BeFree
umls:C1536651Arterial leg ulcer1BeFree
umls:C1566590Delayed Graft Function1GAD
umls:C1696708Prehypertension1RGD
umls:C1709246Non-Neoplastic Disorder1BeFree
umls:C1846064Recurrent infections (sinusitis and bacterial pneumonia and meningitis)1BeFree
umls:C1862939AMYOTROPHIC LATERAL SCLEROSIS 11BeFree
umls:C1955934Trichothiodystrophy Syndromes1BeFree
umls:C2314882Reproductive tract infection1BeFree
umls:C2362324Pediatric Obesity1BeFree
umls:C2747839Radiotoxicity1GAD
umls:C2919828Chronic ulcerative colitis1BeFree
umls:C3249880Solar Erythema1GAD
umls:C3469521FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)1BeFree
umls:C3501835alpha-1-Antitrypsin Deficiency, Autosomal Recessive1BeFree