TissGeneSummary for C1orf94 |
Gene summary |
Basic gene information | Gene symbol | C1orf94 |
Gene name | chromosome 1 open reading frame 94 | |
Synonyms | - | |
Cytomap | UCSC genome browser: 1p34.3 | |
Type of gene | protein-coding | |
RefGenes | NM_001134734.1, NM_032884.4, | |
Description | uncharacterized protein C1orf94 | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000142698 | ||
HPRD : 11310 | ||
Vega : OTTHUMG00000004012 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_C1orf94 | |
BioGPS: 84970 | ||
Pathway | NCI Pathway Interaction Database: C1orf94 | |
KEGG: C1orf94 | ||
REACTOME: C1orf94 | ||
Pathway Commons: C1orf94 | ||
Context | iHOP: C1orf94 | |
ligand binding site mutation search in PubMed: C1orf94 | ||
UCL Cancer Institute: C1orf94 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of C1orf94 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for C1orf94 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for C1orf94 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for C1orf94 |
TissGeneSNV for C1orf94 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.P541S | SKCM | 3 |
p.Q482* | SKCM | 2 |
p.E344K | SKCM | 2 |
p.D261N | SKCM | 2 |
p.D231N | BLCA | 1 |
p.P565S | SKCM | 1 |
p.K257T | STAD | 1 |
p.L162P | ESCA | 1 |
p.G350R | SKCM | 1 |
p.R523C | STAD | 1 |
p.G250V | LUAD | 1 |
p.F598V | STAD | 1 |
p.A214T | ESCA | 1 |
p.G562E | SKCM | 1 |
p.R122K | SKCM | 1 |
p.K213N | COAD | 1 |
p.V189M | SKCM | 1 |
p.G572R | SKCM | 1 |
p.R555Q | UCEC | 1 |
p.P397S | SKCM | 1 |
p.L568F | SKCM | 1 |
p.P111S | BLCA | 1 |
p.L559V | KIRC | 1 |
p.G169V | LUAD | 1 |
p.G440V | LUAD | 1 |
p.S590F | SKCM | 1 |
p.W167L | HNSC | 1 |
p.L239R | SKCM | 1 |
p.H446R | STAD | 1 |
p.Q242H | LUAD | 1 |
p.W271C | LUAD | 1 |
p.R37C | STAD | 1 |
p.R98T | KIRP | 1 |
p.K362E | LUAD | 1 |
p.P382Q | HNSC | 1 |
p.P165T | SKCM | 1 |
p.T439K | LIHC | 1 |
p.P558T | LUAD | 1 |
p.L422P | LUAD | 1 |
p.W461C | LUAD | 1 |
p.E138K | SKCM | 1 |
p.Q14H | UCEC | 1 |
p.K257E | LUAD | 1 |
p.F163S | HNSC | 1 |
p.R222Q | COAD | 1 |
p.P587S | SKCM | 1 |
p.P358S | SKCM | 1 |
p.S85P | UCEC | 1 |
p.K246N | THYM | 1 |
p.F408V | STAD | 1 |
p.G518R | SKCM | 1 |
p.M146I | SKCM | 1 |
p.K385I | LUAD | 1 |
p.S551Y | LUAD | 1 |
p.S351R | LUAD | 1 |
p.E152K | CESC | 1 |
p.D563N | UCEC | 1 |
p.P558H | LUAD | 1 |
p.S170N | CHOL | 1 |
p.F598L | SKCM | 1 |
p.I194V | STAD | 1 |
p.P301S | BLCA | 1 |
p.L184F | SKCM | 1 |
p.G562E | MESO | 1 |
p.A373T | UCEC | 1 |
p.G405V | LUAD | 1 |
p.P168S | SKCM | 1 |
p.S161R | LUAD | 1 |
p.G36S | SKCM | 1 |
p.S141Y | COAD | 1 |
p.G593V | LIHC | 1 |
p.R23S | LIHC | 1 |
p.P486S | SKCM | 1 |
p.P409T | LUSC | 1 |
p.F598V | LUAD | 1 |
p.R312K | SKCM | 1 |
p.R227C | STAD | 1 |
p.S150Y | ACC | 1 |
p.P459Q | LUAD | 1 |
p.P448L | SKCM | 1 |
p.I4V | STAD | 1 |
p.G226S | SKCM | 1 |
p.K252N | BRCA | 1 |
p.A213S | LUSC | 1 |
p.E143* | LIHC | 1 |
p.E416D | ESCA | 1 |
p.R155T | CESC | 1 |
p.G160E | SKCM | 1 |
p.G160R | SKCM | 1 |
p.G407R | SKCM | 1 |
p.P118S | LUAD | 1 |
p.S378* | UCEC | 1 |
p.Q218* | STAD | 1 |
p.R227C | LGG | 1 |
p.K246N | UCEC | 1 |
p.E223* | SARC | 1 |
p.E87D | UCEC | 1 |
p.Q313P | LUAD | 1 |
p.P409L | STAD | 1 |
p.F398I | LUAD | 1 |
p.G595D | ESCA | 1 |
p.R173G | LUAD | 1 |
p.D71N | SKCM | 1 |
p.N553S | SKCM | 1 |
p.L379Q | BLCA | 1 |
p.R412* | SKCM | 1 |
p.R333H | READ | 1 |
p.S577L | SKCM | 1 |
p.E154K | SKCM | 1 |
p.E172K | CESC | 1 |
p.A136V | SKCM | 1 |
p.A214T | HNSC | 1 |
p.Q123P | LUAD | 1 |
p.R332K | BRCA | 1 |
p.G382R | SKCM | 1 |
p.S247Y | LUAD | 1 |
p.R110S | ACC | 1 |
p.K188T | STAD | 1 |
p.D201N | SKCM | 1 |
p.E87D | ESCA | 1 |
p.F243L | UVM | 1 |
p.S361Y | LUAD | 1 |
p.P565L | CESC | 1 |
p.Q537* | SKCM | 1 |
p.R412* | KIRC | 1 |
p.K195I | LUAD | 1 |
p.P468H | LUAD | 1 |
p.A326V | SKCM | 1 |
p.R175S | LIHC | 1 |
p.N597H | UCEC | 1 |
p.Q571* | SKCM | 1 |
p.K67E | LUAD | 1 |
p.E156K | SKCM | 1 |
p.R333C | STAD | 1 |
p.S161R | COAD | 1 |
p.R300S | ACC | 1 |
p.H256R | STAD | 1 |
p.P165L | SKCM | 1 |
p.Y588C | KIRC | 1 |
p.L211V | LUSC | 1 |
p.G595D | LGG | 1 |
p.C212* | ESCA | 1 |
p.G350E | SKCM | 1 |
p.W357L | HNSC | 1 |
p.D41N | BLCA | 1 |
p.K267N | LUAD | 1 |
p.L395I | PAAD | 1 |
p.T284K | CESC | 1 |
p.A300V | COAD | 1 |
p.P324L | PAAD | 1 |
p.P308S | LUAD | 1 |
p.G595V | LUAD | 1 |
p.D432Y | LUAD | 1 |
p.C212X | ESCA | 1 |
p.F353S | HNSC | 1 |
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TissGeneCNV for C1orf94 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for C1orf94 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for C1orf94 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for C1orf94 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for C1orf94 |
TissGeneDrug for C1orf94 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for C1orf94 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0027819 | Neuroblastoma | 1 | GAD |