![]() |
TissGeneSummary for KRT37 |
![]() |
Basic gene information | Gene symbol | KRT37 |
Gene name | keratin 37 | |
Synonyms | HA7|K37|KRTHA7 | |
Cytomap | UCSC genome browser: 17q21.2 | |
Type of gene | protein-coding | |
RefGenes | NM_003770.4, | |
Description | hair keratin, type I Ha7keratin, hair, acidic, 7keratin, type I cuticular Ha7keratin-37 | |
Modification date | 20141207 | |
dbXrefs | MIM : 604541 | |
HGNC : HGNC | ||
Ensembl : ENSG00000108417 | ||
HPRD : 05175 | ||
Vega : OTTHUMG00000133606 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_KRT37 | |
BioGPS: 8688 | ||
Pathway | NCI Pathway Interaction Database: KRT37 | |
KEGG: KRT37 | ||
REACTOME: KRT37 | ||
Pathway Commons: KRT37 | ||
Context | iHOP: KRT37 | |
ligand binding site mutation search in PubMed: KRT37 | ||
UCL Cancer Institute: KRT37 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | TiGER,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | ColonSkin | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | COADSKCM | |
Reference showing the relevant tissue of KRT37 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
![]() |
GO ID | GO term | PubMed ID |
Top |
TissGeneExp for KRT37 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
![]() |
![]() (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
![]() |
![]() (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
![]() |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
![]() |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
BRCA | -0.236357651 | -1.589600633 | 1.353242982 | 3.09E-14 | 1.53E-13 |
Top |
TissGene-miRNA for KRT37 |
![]() (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
Top |
TissGeneMut for KRT37 |
TissGeneSNV for KRT37 |
![]() Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
![]() |
![]() |
![]() (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
![]() |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.E400K | SKCM | 3 |
p.G274E | SKCM | 2 |
p.R277W | GBM | 1 |
p.G209R | LGG | 1 |
p.Q252* | SKCM | 1 |
p.P416T | LUAD | 1 |
p.T422M | COAD | 1 |
p.P65S | LUAD | 1 |
p.V49M | UCEC | 1 |
p.C315Y | UCEC | 1 |
p.D206N | LIHC | 1 |
p.R123C | COAD | 1 |
p.G438E | SKCM | 1 |
p.A217V | COAD | 1 |
p.E411K | CESC | 1 |
p.Q252X | SKCM | 1 |
p.A186S | LUSC | 1 |
p.E255K | SKCM | 1 |
p.N418S | GBM | 1 |
p.T326M | HNSC | 1 |
p.A306D | COAD | 1 |
p.E234G | UCEC | 1 |
p.E144* | SKCM | 1 |
p.G93E | GBM | 1 |
p.T72A | COAD | 1 |
p.P70L | SKCM | 1 |
p.H242D | LUSC | 1 |
p.R405P | SKCM | 1 |
p.C10F | DLBC | 1 |
p.K232N | PAAD | 1 |
p.E260K | SKCM | 1 |
p.A360P | KIRP | 1 |
p.H200Y | LUAD | 1 |
p.E225K | STAD | 1 |
p.S9L | BLCA | 1 |
p.E104K | SKCM | 1 |
p.N48K | LUAD | 1 |
p.A402D | LIHC | 1 |
p.E260* | LUAD | 1 |
p.R156C | SKCM | 1 |
p.E138K | SKCM | 1 |
p.E311K | UCEC | 1 |
p.E260K | GBM | 1 |
p.R64C | ESCA | 1 |
p.A173V | STAD | 1 |
p.V49L | LUAD | 1 |
p.L253Q | LUAD | 1 |
p.S9L | SKCM | 1 |
p.G13C | BRCA | 1 |
p.R54K | SKCM | 1 |
p.V332E | LUAD | 1 |
p.R156C | DLBC | 1 |
p.E245K | SKCM | 1 |
p.R405Q | UCEC | 1 |
p.K247N | STAD | 1 |
p.I91T | UCEC | 1 |
p.P27S | SKCM | 1 |
p.A52T | COAD | 1 |
p.Q227H | UCEC | 1 |
p.T326M | COAD | 1 |
p.S168I | ESCA | 1 |
p.E138K | COAD | 1 |
p.S431N | READ | 1 |
p.E106D | READ | 1 |
p.Q345H | UCEC | 1 |
p.N39S | COAD | 1 |
p.A116V | LGG | 1 |
p.E106K | SKCM | 1 |
p.R258W | COAD | 1 |
p.Q227* | LUAD | 1 |
p.Q235X | COAD | 1 |
p.A217T | PRAD | 1 |
p.N287D | PRAD | 1 |
p.D223E | LUAD | 1 |
p.K341N | LUAD | 1 |
p.H242N | HNSC | 1 |
p.D223Y | LUAD | 1 |
Top |
TissGeneCNV for KRT37 |
![]() (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
![]() |
Top |
TissGeneFusions for KRT37 |
![]() (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Top |
TissGeneNet for KRT37 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
Top |
TissGeneProg for KRT37 |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
![]() |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
![]() |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
![]() |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
![]() |
Top |
TissGeneClin for KRT37 |
TissGeneDrug for KRT37 |
![]() (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
TissGeneDisease for KRT37 |
![]() (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |