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| TissGeneSummary for CCNA1 |
 Gene summary |
| Basic gene information | Gene symbol | CCNA1 |
| Gene name | cyclin A1 | |
| Synonyms | CT146 | |
| Cytomap | UCSC genome browser: 13q12.3-q13 | |
| Type of gene | protein-coding | |
| RefGenes | NM_001111045.1, NM_001111046.1,NM_001111047.1,NM_003914.3, | |
| Description | cyclin-A1 | |
| Modification date | 20141207 | |
| dbXrefs | MIM : 604036 | |
| HGNC : HGNC | ||
| Ensembl : ENSG00000133101 | ||
| HPRD : 04946 | ||
| Vega : OTTHUMG00000016733 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_CCNA1 | |
| BioGPS: 8900 | ||
| Pathway | NCI Pathway Interaction Database: CCNA1 | |
| KEGG: CCNA1 | ||
| REACTOME: CCNA1 | ||
| Pathway Commons: CCNA1 | ||
| Context | iHOP: CCNA1 | |
| ligand binding site mutation search in PubMed: CCNA1 | ||
| UCL Cancer Institute: CCNA1 | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | TiGER,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Bone marrowTestis | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | LAMLTGCT | |
| Reference showing the relevant tissue of CCNA1 | ||
| Description by TissGene annotations | ||
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
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| TissGeneExp for CCNA1 |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| HNSC | 2.985542445 | 0.697212213 | 2.288330233 | 1.83E-05 | 9.78E-05 |
| THCA | 0.766071968 | -1.273846676 | 2.039918644 | 1.10E-09 | 6.31E-09 |
| KIRC | -2.329671605 | -1.174520216 | -1.155151389 | 1.72E-07 | 4.71E-07 |
| STAD | -2.772939314 | -1.282270564 | -1.49066875 | 5.43E-07 | 1.00E-05 |
| LUAD | -0.422723473 | 1.057036872 | -1.479760345 | 0.000213 | 0.000509338 |
| COAD | -2.946023208 | -1.760669362 | -1.185353846 | 0.00011 | 0.000395098 |
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| TissGene-miRNA for CCNA1 |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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| TissGeneMut for CCNA1 |
| TissGeneSNV for CCNA1 |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.V315I | COAD | 2 |
| p.D315N | SKCM | 2 |
| p.S13F | COAD | 1 |
| p.D139N | SKCM | 1 |
| p.H426Y | SKCM | 1 |
| p.V358I | HNSC | 1 |
| p.E26K | STAD | 1 |
| p.D377H | LUAD | 1 |
| p.S415* | UCEC | 1 |
| p.L462F | SKCM | 1 |
| p.M138I | SKCM | 1 |
| p.M326V | SKCM | 1 |
| p.Y22N | COAD | 1 |
| p.S110P | LIHC | 1 |
| p.G16W | THYM | 1 |
| p.Q437K | SKCM | 1 |
| p.Q350* | CESC | 1 |
| p.R353Q | ESCA | 1 |
| p.G289E | SKCM | 1 |
| p.G27E | SKCM | 1 |
| p.R360K | STAD | 1 |
| p.T240M | UCEC | 1 |
| p.Q36H | COAD | 1 |
| p.L228M | COAD | 1 |
| p.A112D | HNSC | 1 |
| p.E2D | LUAD | 1 |
| p.P377A | HNSC | 1 |
| p.R278Q | COAD | 1 |
| p.R354Q | ESCA | 1 |
| p.A65G | LIHC | 1 |
| p.E43G | HNSC | 1 |
| p.K449R | STAD | 1 |
| p.P79L | SKCM | 1 |
| p.H383Y | SKCM | 1 |
| p.L200I | ESCA | 1 |
| p.I303M | STAD | 1 |
| p.P115A | HNSC | 1 |
| p.W360R | LGG | 1 |
| p.R50M | COAD | 1 |
| p.T315N | LUAD | 1 |
| p.E406A | STAD | 1 |
| p.D249V | STAD | 1 |
| p.E300K | SKCM | 1 |
| p.L122H | ESCA | 1 |
| p.C452Y | OV | 1 |
| p.E42G | HNSC | 1 |
| p.G41W | COAD | 1 |
| p.D376H | LUAD | 1 |
| p.P79S | SKCM | 1 |
| p.G27R | SKCM | 1 |
| p.S108T | GBM | 1 |
| p.R94W | CESC | 1 |
| p.E213A | HNSC | 1 |
| p.R359S | LUAD | 1 |
| p.M455I | SKCM | 1 |
| p.L305F | SKCM | 1 |
| p.R244H | UCEC | 1 |
| p.D272N | SKCM | 1 |
| p.T264A | UCEC | 1 |
| p.K233Q | SKCM | 1 |
| p.R146K | SKCM | 1 |
| p.T70P | STAD | 1 |
| p.G255V | LUAD | 1 |
| p.V357M | PAAD | 1 |
| p.P73T | OV | 1 |
| p.V186I | BLCA | 1 |
| p.D316N | SKCM | 1 |
| p.Q132K | SARC | 1 |
| p.L121H | ESCA | 1 |
| p.I104S | UCS | 1 |
| p.L411F | SKCM | 1 |
| p.G254V | LUAD | 1 |
| p.T320A | STAD | 1 |
| p.L190I | PAAD | 1 |
| p.L454F | SKCM | 1 |
| p.S13C | HNSC | 1 |
| p.P140S | SKCM | 1 |
| p.V187I | BLCA | 1 |
| p.D273N | SKCM | 1 |
| p.V254G | LUAD | 1 |
| p.L386V | LUAD | 1 |
| p.P378A | HNSC | 1 |
| p.R61X | READ | 1 |
| p.P304S | SKCM | 1 |
| p.P183S | SKCM | 1 |
| p.R360S | LUSC | 1 |
| p.L191I | PAAD | 1 |
| p.T69P | STAD | 1 |
| p.T314N | LUAD | 1 |
| p.L385V | LUAD | 1 |
| p.F336Y | BLCA | 1 |
| p.K259E | LIHC | 1 |
| p.K234T | STAD | 1 |
| p.Y10C | READ | 1 |
| p.V359I | HNSC | 1 |
| p.T407N | BRCA | 1 |
| p.T101R | SKCM | 1 |
| p.E309K | SKCM | 1 |
| p.S48N | PAAD | 1 |
| p.E26K | PRAD | 1 |
| p.M95I | SKCM | 1 |
| p.S107F | BLCA | 1 |
| p.P122S | SKCM | 1 |
| p.I103S | UCS | 1 |
| p.E170X | COAD | 1 |
| p.R261* | UCEC | 1 |
| p.P122L | SKCM | 1 |
| p.M412I | SKCM | 1 |
| p.P114A | HNSC | 1 |
| p.V356M | PAAD | 1 |
| p.Q355H | UCEC | 1 |
| p.W403R | LGG | 1 |
| p.L348F | SKCM | 1 |
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| TissGeneCNV for CCNA1 |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| TissGeneFusions for CCNA1 |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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| TissGeneNet for CCNA1 |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| BRCA (tumor) | BRCA (normal) |
| CCNA1, KIAA0101, SRC, MCM3, CDK2, TCF4, MCM2, PARK2, MCM4, PGR, PAICS, CDT1, MTHFD1, CKS2, USP2, CDC20, CUX1, TGFB1I1, XPO5, OAT, KLHDC9 (tumor) | CCNA1, CUL1, MCM3, SKP2, HIST1H1B, ARID2, PGR, MCM6, USP2, MYBL2, CDC25A, HIST1H1A, CDC20, ACAT2, ACLY, GOT2, XPO5, CABLES1, KLHDC9, CKS1B, STOML2 (normal) |
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| COAD (tumor) | COAD (normal) |
| CCNA1, COPS6, PPP1CA, CDKN1A, SRC, VHL, CUL1, TCF4, PARK2, PSMD6, MCC, PGR, NPAT, CDT1, USP2, MYBL2, TUFM, TGFB1I1, CABLES1, ATXN2L, LARP4B (tumor) | CCNA1, BRCA1, KIAA0101, E2F1, CDK1, CDK2, TCF4, LRPPRC, MCC, PGR, PAICS, CDT1, CKS2, LRRC59, CDC25A, TUFM, CDC20, TGFB1I1, GOT2, CKS1B, STOML2 (normal) |
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| HNSC (tumor) | HNSC (normal) |
| CCNA1, KIAA1967, BRCA1, CDKN1A, SP1, RBL2, VHL, CUL1, EP300, SKP2, MCM4, TRIM28, RB1, ARID2, CSNK1E, RPA1, RBL1, CDKN1B, MTHFD1, ACAT2, PROCA1 (tumor) | CCNA1, KIAA1967, BRCA1, KIAA0101, E2F1, MCM3, CDK1, MCM2, SEC13, MCC, CDKN1B, MCM6, CDT1, LRRC59, USP2, CDC25A, ACLY, GOT2, XPO5, CABLES1, PROCA1 (normal) |
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| KICH (tumor) | KICH (normal) |
| CCNA1, BRCA1, CDKN1A, E2F1, CDK2, MCM2, LRPPRC, SEC13, MCM4, RB1, PPP2CB, PGR, CSNK1E, CDKN1B, NPAT, MTHFD1, CUX1, OAT, INCA1, RBM4, STOML2 (tumor) | CCNA1, CDKN1A, SRC, CUL1, COPS5, MCM2, SEC13, PSMD6, GNB2L1, PAICS, CKS2, CDC20, CUX1, XPO5, CABLES1, OAT, RBM4, ATXN2L, STOML2, LARP4B, VPS18 (normal) |
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| KIRC (tumor) | KIRC (normal) |
| CCNA1, CDKN1A, KIAA0101, CDK1, CDK2, TCF4, MCM2, PARK2, RB1, PPP2CB, PAICS, MCM6, MTHFD1, FZR1, LRRC59, USP2, XRCC6, CUX1, CAPZA1, GPS2, CKS1B (tumor) | CCNA1, SRC, E2F1, CDK1, CDK2, MCM2, LRPPRC, CSNK1D, PARK2, SEC13, PSMD6, HIST1H1B, MCM4, TRIM28, CDT1, CKS2, MYBL2, CDC25A, CDC20, ACLY, CABLES1 (normal) |
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| KIRP (tumor) | KIRP (normal) |
| CCNA1, CDKN1A, RBL2, CDK1, CDK2, LRPPRC, PARK2, RB1, PPP2CB, MCM6, NPAT, MTHFD1, LRRC59, CDC25A, TUFM, CDC20, XRCC6, CAPZA1, GOT2, PFAS, STOML2 (tumor) | CCNA1, COPS6, MCM3, TCF4, LRPPRC, SEC13, EP300, TRIM28, RB1, ARID2, PGR, CSNK1E, CDKN1B, MTHFD1, USP2, TUFM, CUX1, ACLY, GOT2, GPS2, LARP4B (normal) |
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| LIHC (tumor) | LIHC (normal) |
| CCNA1, SRC, GANAB, COPS5, PARK2, SKP2, EIF3I, APEX1, RB1, CSNK1E, MCM6, MTHFD1, HIST1H1A, TUFM, CUX1, CAPZA1, GPS2, INCA1, RBM4, ATXN2L, PROCA1 (tumor) | CCNA1, KIAA1967, KIAA0101, SRC, CDK1, CDK2, TCF4, TRIM28, RB1, PGR, CSNK1E, RPA1, NPAT, MTHFD1, MYBL2, TGFB1I1, CAPZA1, ACLY, GOT2, ATXN2L, LARP4B (normal) |
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| LUAD (tumor) | LUAD (normal) |
| CCNA1, COPS6, KIAA1967, BRCA1, CDKN1A, CUL1, CDK2, TCF4, MCM2, LRPPRC, HIST1H1B, MCM4, RPA1, PAICS, SRY, USP2, TGFB1I1, OAT, KLHDC9, CKS1B, PROCA1 (tumor) | CCNA1, CDKN1A, TCF4, LRPPRC, PTK2, CSNK1D, PARK2, MCC, PPP2CB, PGR, FZR1, USP2, TGFB1I1, ACLY, PFAS, XPO5, CABLES1, OAT, RBM4, LARP4B, VPS18 (normal) |
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| LUSC (tumor) | LUSC (normal) |
| CCNA1, KIAA1967, BRCA1, GANAB, CUL1, LRPPRC, PARK2, PSMD6, EIF3F, TRIM28, GNB2L1, MTHFD1, SRY, USP2, HIST1H1A, CAPZA1, PFAS, CABLES1, OAT, KLHDC9, PROCA1 (tumor) | CCNA1, COPS6, CDKN1A, CUL1, TCF4, PTK2, CSNK1D, PSMD6, MCC, HIST1H1B, PPP2CB, RPA1, CKS2, LRRC59, HIST1H1A, GOT2, CABLES1, RBM4, ATXN2L, STOML2, LARP4B (normal) |
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| PRAD (tumor) | PRAD (normal) |
| CCNA1, PPP1CA, CDKN1A, VHL, GANAB, PTK2, EIF3I, MCM4, TRIM28, GNB2L1, PAICS, RBL1, NPAT, TUFM, CUX1, ACAT2, ACLY, GOT2, CABLES1, RBM4, KLHDC9 (tumor) | CCNA1, PPP1CA, CDKN1A, GANAB, CUL1, TCF4, MCC, EIF3I, APEX1, TRIM28, PPP2CB, PGR, GNB2L1, PAICS, MCM6, USP2, CDC25A, TGFB1I1, CABLES1, RBM4, LARP4B (normal) |
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| STAD (tumor) | STAD (normal) |
| CCNA1, KIAA0101, E2F1, CUL1, CDK1, TCF4, MCM2, PARK2, MCM4, PGR, CDT1, MTHFD1, MYBL2, CDC25A, TUFM, CDC20, TGFB1I1, ACAT2, CABLES1, KLHDC9, LARP4B (tumor) | CCNA1, PPP1CA, KIAA0101, E2F1, MCM3, CDK1, TCF4, PARK2, MCC, MCM4, PGR, PAICS, CDT1, MTHFD1, USP2, MYBL2, CDC25A, TUFM, CDC20, TGFB1I1, ACAT2 (normal) |
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| THCA (tumor) | THCA (normal) |
| CCNA1, CDKN1A, SP1, KIAA0101, E2F1, GANAB, CUL1, COPS5, CDK2, PTK2, PARK2, PSMD6, HIST1H1B, CKS2, MYBL2, CDC20, CUX1, CABLES1, RBM4, LARP4B, PROCA1 (tumor) | CCNA1, CDKN1A, SRC, CDK2, TCF4, PARK2, MCM4, APEX1, PGR, CSNK1E, MCM6, CKS2, USP2, MYBL2, CDC25A, XRCC6, CUX1, TGFB1I1, CAPZA1, GOT2, CABLES1 (normal) |
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| TissGeneProg for CCNA1 |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| TissGeneClin for CCNA1 |
| TissGeneDrug for CCNA1 |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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| TissGeneDisease for CCNA1 |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0023467 | Leukemia, Myelocytic, Acute | 11 | BeFree |
| umls:C0007847 | Malignant tumor of cervix | 8 | BeFree |
| umls:C0302592 | Cervix carcinoma | 8 | BeFree |
| umls:C0023418 | leukemia | 7 | BeFree,LHGDN |
| umls:C1168401 | Squamous cell carcinoma of the head and neck | 5 | BeFree,CTD_human |
| umls:C0007137 | Squamous cell carcinoma | 3 | BeFree |
| umls:C0027627 | Neoplasm Metastasis | 3 | BeFree |
| umls:C0376358 | Malignant neoplasm of prostate | 3 | BeFree |
| umls:C0596263 | Carcinogenesis | 3 | BeFree |
| umls:C0600139 | Prostate carcinoma | 3 | BeFree |
| umls:C0678222 | Breast Carcinoma | 3 | BeFree |
| umls:C1334177 | Infiltrating Cervical Carcinoma | 3 | BeFree |
| umls:C0004509 | Azoospermia | 2 | BeFree |
| umls:C0006142 | Malignant neoplasm of breast | 2 | BeFree |
| umls:C0009402 | Colorectal Carcinoma | 2 | BeFree |
| umls:C0023449 | Acute lymphocytic leukemia | 2 | BeFree |
| umls:C0033578 | Prostatic Neoplasms | 2 | BeFree,LHGDN |
| umls:C0153594 | Malignant neoplasm of testis | 2 | BeFree |
| umls:C0333875 | High-Grade Squamous Intraepithelial Lesions | 2 | BeFree |
| umls:C0598766 | Leukemogenesis | 2 | BeFree |
| umls:C0684249 | Carcinoma of lung | 2 | BeFree |
| umls:C0751688 | Malignant Squamous Cell Neoplasm | 2 | BeFree |
| umls:C1302773 | Low Grade Squamous Intraepithelial Neoplasia | 2 | BeFree |
| umls:C1527249 | Colorectal Cancer | 2 | BeFree |
| umls:C1961102 | Precursor Cell Lymphoblastic Leukemia Lymphoma | 2 | BeFree |
| umls:C0005684 | Malignant neoplasm of urinary bladder | 1 | BeFree |
| umls:C0005695 | Bladder Neoplasm | 1 | BeFree |
| umls:C0007134 | Renal Cell Carcinoma | 1 | BeFree |
| umls:C0007868 | Cervical dysplasia | 1 | BeFree |
| umls:C0018939 | Hematological Disease | 1 | BeFree |
| umls:C0019693 | HIV Infections | 1 | BeFree |
| umls:C0021364 | Male infertility | 1 | BeFree,GAD |
| umls:C0023464 | Acute biphenotypic leukemia | 1 | BeFree |
| umls:C0023473 | Myeloid Leukemia, Chronic | 1 | BeFree |
| umls:C0023890 | Liver Cirrhosis | 1 | BeFree |
| umls:C0026764 | Multiple Myeloma | 1 | BeFree |
| umls:C0035369 | Retroviridae Infections | 1 | BeFree |
| umls:C0206708 | Cervical Intraepithelial Neoplasia | 1 | BeFree |
| umls:C0238461 | Anaplastic thyroid carcinoma | 1 | BeFree |
| umls:C0242379 | Malignant neoplasm of lung | 1 | BeFree |
| umls:C0278996 | Cancer of Head and Neck | 1 | BeFree |
| umls:C0349459 | Cervical intraepithelial neoplasia grade 2 | 1 | BeFree |
| umls:C0376545 | Hematologic Neoplasms | 1 | BeFree |
| umls:C0686619 | Secondary malignant neoplasm of lymph node | 1 | BeFree |
| umls:C0699885 | Carcinoma of bladder | 1 | BeFree |
| umls:C0855197 | Testicular malignant germ cell tumor | 1 | BeFree |
| umls:C0950124 | Papillomavirus Infections | 1 | CTD_human |
| umls:C1140680 | Malignant neoplasm of ovary | 1 | GAD |
| umls:C1332922 | Cervical Squamous Intraepithelial Neoplasia | 1 | BeFree |
| umls:C1334011 | High Grade Cervical Intraepithelial Neoplasia | 1 | BeFree |
| umls:C1384583 | Congenital absence of germinal epithelium of testes | 1 | BeFree |
| umls:C1458155 | Mammary Neoplasms | 1 | BeFree |
| umls:C1561955 | Fibrinogen Adverse Event | 1 | GAD |
| umls:C1623038 | Cirrhosis | 1 | BeFree |
| umls:C2239176 | Liver carcinoma | 1 | CTD_human |
| umls:C2931822 | Nasopharyngeal carcinoma | 1 | BeFree |
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