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| TissGeneSummary for ZNF479 |
 Gene summary |
| Basic gene information | Gene symbol | ZNF479 |
| Gene name | zinc finger protein 479 | |
| Synonyms | KR19 | |
| Cytomap | UCSC genome browser: 7p11.2 | |
| Type of gene | protein-coding | |
| RefGenes | NM_033273.1, | |
| Description | HKr19KRAB zinc finger protein KR19zinc finger protein Kr19 | |
| Modification date | 20141207 | |
| dbXrefs | HGNC : HGNC | |
| Ensembl : ENSG00000185177 | ||
| Vega : OTTHUMG00000156682 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_ZNF479 | |
| BioGPS: 90827 | ||
| Pathway | NCI Pathway Interaction Database: ZNF479 | |
| KEGG: ZNF479 | ||
| REACTOME: ZNF479 | ||
| Pathway Commons: ZNF479 | ||
| Context | iHOP: ZNF479 | |
| ligand binding site mutation search in PubMed: ZNF479 | ||
| UCL Cancer Institute: ZNF479 | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | HPA,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
| Reference showing the relevant tissue of ZNF479 | ||
| Description by TissGene annotations | TissgsKTS CNV lost TissGeneKTS | |
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
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| TissGeneExp for ZNF479 |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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| TissGene-miRNA for ZNF479 |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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| TissGeneMut for ZNF479 |
| TissGeneSNV for ZNF479 |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.K438T | LUAD | 5 |
| p.R11Q | SKCM | 3 |
| p.R295K | CESC | 3 |
| p.H459Y | SKCM | 2 |
| p.W336C | LIHC | 2 |
| p.H319Y | SKCM | 2 |
| p.R38Q | SKCM | 2 |
| p.G471D | UCEC | 2 |
| p.R429I | UCEC | 2 |
| p.R261K | SKCM | 2 |
| p.H487Y | SKCM | 2 |
| p.G9* | LUAD | 2 |
| p.S281Y | LUSC | 1 |
| p.S366L | SKCM | 1 |
| p.F185I | KIRC | 1 |
| p.M82I | SKCM | 1 |
| p.Q95E | ACC | 1 |
| p.R457K | SKCM | 1 |
| p.E462K | SKCM | 1 |
| p.C325W | LUAD | 1 |
| p.G167S | SKCM | 1 |
| p.E441K | BLCA | 1 |
| p.R485I | UCEC | 1 |
| p.C299S | ESCA | 1 |
| p.L448V | THCA | 1 |
| p.R457K | BLCA | 1 |
| p.K232N | LUAD | 1 |
| p.K189T | KIRC | 1 |
| p.A395E | UCEC | 1 |
| p.R258I | UCEC | 1 |
| p.N339T | LUAD | 1 |
| p.H319Y | LUAD | 1 |
| p.R373K | SKCM | 1 |
| p.C148R | LUAD | 1 |
| p.S212F | BLCA | 1 |
| p.P87Q | LUAD | 1 |
| p.R295T | HNSC | 1 |
| p.Q75H | LUAD | 1 |
| p.Q276K | UCEC | 1 |
| p.V165L | UCS | 1 |
| p.K260R | THYM | 1 |
| p.R401T | KIRP | 1 |
| p.H455N | LUAD | 1 |
| p.E12X | COAD | 1 |
| p.Q147K | SARC | 1 |
| p.G237* | BLCA | 1 |
| p.R317K | BLCA | 1 |
| p.Y49F | LUAD | 1 |
| p.H263N | READ | 1 |
| p.R463I | LUSC | 1 |
| p.H505R | LUSC | 1 |
| p.G471S | OV | 1 |
| p.T151A | HNSC | 1 |
| p.H263Y | SKCM | 1 |
| p.K85N | ESCA | 1 |
| p.E294D | BLCA | 1 |
| p.E238D | UCEC | 1 |
| p.V137L | LGG | 1 |
| p.S150T | LUAD | 1 |
| p.K3T | UCEC | 1 |
| p.F278Y | LUAD | 1 |
| p.R349G | CESC | 1 |
| p.C470Y | LGG | 1 |
| p.R280H | PRAD | 1 |
| p.E322K | SKCM | 1 |
| p.S338L | BLCA | 1 |
| p.R289I | STAD | 1 |
| p.L508I | UCEC | 1 |
| p.I233K | SKCM | 1 |
| p.G167R | OV | 1 |
| p.E121K | SKCM | 1 |
| p.K61M | LUAD | 1 |
| p.G140R | HNSC | 1 |
| p.E245* | LUSC | 1 |
| p.K186N | LIHC | 1 |
| p.T320N | LUAD | 1 |
| p.H160Y | SKCM | 1 |
| p.S212Y | HNSC | 1 |
| p.K351E | LIHC | 1 |
| p.G119* | LUAD | 1 |
| p.D20N | SKCM | 1 |
| p.C129F | HNSC | 1 |
| p.E81K | SKCM | 1 |
| p.G331D | HNSC | 1 |
| p.P296H | LUAD | 1 |
| p.Y142X | STAD | 1 |
| p.K78* | BLCA | 1 |
| p.S419I | LUAD | 1 |
| p.L27M | LUAD | 1 |
| p.S170* | LUSC | 1 |
| p.V53F | HNSC | 1 |
| p.P492H | STAD | 1 |
| p.H455N | KIRC | 1 |
| p.N286K | CESC | 1 |
| p.L508I | LUAD | 1 |
| p.E462* | LUAD | 1 |
| p.R261I | UCEC | 1 |
| p.K438T | PRAD | 1 |
| p.R38Q | GBM | 1 |
| p.L284V | HNSC | 1 |
| p.R373I | UCEC | 1 |
| p.S281Y | LUAD | 1 |
| p.R345I | BLCA | 1 |
| p.Y353C | LUAD | 1 |
| p.R349G | OV | 1 |
| p.K122T | CESC | 1 |
| p.Y521C | UCEC | 1 |
| p.T423N | LUAD | 1 |
| p.P7H | LUSC | 1 |
| p.C523F | KIRC | 1 |
| p.N367K | BLCA | 1 |
| p.S74F | UCEC | 1 |
| p.W336L | LIHC | 1 |
| p.R174T | HNSC | 1 |
| p.P99Q | LUAD | 1 |
| p.R19T | LGG | 1 |
| p.G517V | LUAD | 1 |
| p.S281F | SKCM | 1 |
| p.H483N | BRCA | 1 |
| p.K126R | BLCA | 1 |
| p.L256I | LUAD | 1 |
| p.G321V | LUAD | 1 |
| p.T516N | LUAD | 1 |
| p.E350G | SARC | 1 |
| p.V88_splice | LUSC | 1 |
| p.E121D | READ | 1 |
| p.G237V | LUAD | 1 |
| p.S337Y | HNSC | 1 |
| p.S150* | LUAD | 1 |
| p.L33Q | LIHC | 1 |
| p.T432N | UCEC | 1 |
| p.A277D | LUSC | 1 |
| p.G293E | SKCM | 1 |
| p.T479A | SKCM | 1 |
| p.R345K | SKCM | 1 |
| p.H515Y | HNSC | 1 |
| p.R295I | LUAD | 1 |
| p.V145I | LGG | 1 |
| p.E28K | SKCM | 1 |
| p.Y381C | STAD | 1 |
| p.G443S | HNSC | 1 |
| p.R485I | COAD | 1 |
| p.H287N | LUAD | 1 |
| p.E490* | LUAD | 1 |
| p.Q388H | LUAD | 1 |
| p.K164I | LUSC | 1 |
| p.Y493* | LUSC | 1 |
| p.S310* | CESC | 1 |
| p.K232* | HNSC | 1 |
| p.Q276H | OV | 1 |
| p.R50I | COAD | 1 |
| p.R435K | ESCA | 1 |
| p.A354T | HNSC | 1 |
| p.E29K | OV | 1 |
| p.R345I | UCEC | 1 |
| p.R50I | LUSC | 1 |
| p.R90H | CESC | 1 |
| p.R42T | READ | 1 |
| p.R345T | OV | 1 |
| p.Q153K | LUAD | 1 |
| p.E29* | LUSC | 1 |
| p.R485K | SKCM | 1 |
| p.E28Q | HNSC | 1 |
| p.Q360K | LUAD | 1 |
| p.E524* | LUAD | 1 |
| p.S226P | LUAD | 1 |
| p.H160Y | ESCA | 1 |
| p.E468D | LUSC | 1 |
| p.R317I | UCEC | 1 |
| p.E322A | HNSC | 1 |
| p.S193L | SKCM | 1 |
| p.R261I | UCS | 1 |
| p.T453I | STAD | 1 |
| p.K438T | GBM | 1 |
| p.I233T | LGG | 1 |
| p.W252* | SKCM | 1 |
| p.S363N | LUAD | 1 |
| p.R261I | READ | 1 |
| p.L55M | LUAD | 1 |
| p.R317K | UCEC | 1 |
| p.D43G | STAD | 1 |
| p.K267T | READ | 1 |
| p.C330W | LUAD | 1 |
| p.H375Q | DLBC | 1 |
| p.H459N | LUSC | 1 |
| p.E496D | LUAD | 1 |
| p.R392H | PAAD | 1 |
| p.S310P | STAD | 1 |
| p.R342G | COAD | 1 |
| p.E121D | UCEC | 1 |
| p.P87S | UCEC | 1 |
| p.E69Q | LUAD | 1 |
| p.E47V | THYM | 1 |
| p.Y142* | STAD | 1 |
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| TissGeneCNV for ZNF479 |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| TissGeneFusions for ZNF479 |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| Chimerdb3.0 | ChiTaRs | NA | AW272393 | RIN2-ZNF479 | chr20:19876591 | chr7:57199992 |
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| TissGeneNet for ZNF479 |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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| TissGeneProg for ZNF479 |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| TissGeneClin for ZNF479 |
| TissGeneDrug for ZNF479 |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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| TissGeneDisease for ZNF479 |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
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