TissGeneSummary for NUP210L |
Gene summary |
Basic gene information | Gene symbol | NUP210L |
Gene name | nucleoporin 210kDa-like | |
Synonyms | - | |
Cytomap | UCSC genome browser: 1q21.3 | |
Type of gene | protein-coding | |
RefGenes | NM_001159484.1, NM_207308.2, | |
Description | nuclear pore membrane glycoprotein 210-likenuclear pore membrane glycoprotein 210-like (LOC91181)nucleoporin Nup210-like | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000143552 | ||
HPRD : 14852 | ||
Vega : OTTHUMG00000035852 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_NUP210L | |
BioGPS: 91181 | ||
Pathway | NCI Pathway Interaction Database: NUP210L | |
KEGG: NUP210L | ||
REACTOME: NUP210L | ||
Pathway Commons: NUP210L | ||
Context | iHOP: NUP210L | |
ligand binding site mutation search in PubMed: NUP210L | ||
UCL Cancer Institute: NUP210L | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | ||
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of NUP210L | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
Top |
TissGeneExp for NUP210L |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
LUSC | -1.805537028 | -0.559540949 | -1.245996078 | 1.70E-08 | 5.22E-08 |
Top |
TissGene-miRNA for NUP210L |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
Top |
TissGeneMut for NUP210L |
TissGeneSNV for NUP210L |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.E672K | SKCM | 2 |
p.R754C | SKCM | 2 |
p.R734* | GBM | 2 |
p.R734Q | LGG | 2 |
p.A622T | PAAD | 2 |
p.P365S | KIRP | 1 |
p.S1557T | THCA | 1 |
p.P789S | SKCM | 1 |
p.E503D | LUSC | 1 |
p.P288L | SKCM | 1 |
p.R1531M | PAAD | 1 |
p.P464S | SKCM | 1 |
p.A580D | ESCA | 1 |
p.E538* | UCEC | 1 |
p.P236S | STAD | 1 |
p.E1361Q | BLCA | 1 |
p.G740V | LUAD | 1 |
p.Y352C | SKCM | 1 |
p.G480R | SKCM | 1 |
p.G214* | LUSC | 1 |
p.Y419* | LUAD | 1 |
p.K470T | UCEC | 1 |
p.S1256N | SKCM | 1 |
p.E183* | UCEC | 1 |
p.H572Y | BLCA | 1 |
p.R1382P | BLCA | 1 |
p.Q62* | LIHC | 1 |
p.T1187I | LIHC | 1 |
p.P1475S | BLCA | 1 |
p.V1123A | STAD | 1 |
p.L1007R | STAD | 1 |
p.Q1111R | STAD | 1 |
p.I683V | SKCM | 1 |
p.R734X | LGG | 1 |
p.L990M | ESCA | 1 |
p.R688Q | BLCA | 1 |
p.A775V | LGG | 1 |
p.A1452P | LUSC | 1 |
p.L1850V | BLCA | 1 |
p.L742R | HNSC | 1 |
p.E1046Q | HNSC | 1 |
p.N812K | KIRC | 1 |
p.E1727K | BLCA | 1 |
p.P288H | THYM | 1 |
p.A656P | KIRP | 1 |
p.D596N | SKCM | 1 |
p.S884A | SKCM | 1 |
p.F358I | OV | 1 |
p.E1039D | LGG | 1 |
p.S1117F | SKCM | 1 |
p.Y641* | BLCA | 1 |
p.Q722P | LUAD | 1 |
p.M1614I | DLBC | 1 |
p.W820* | SKCM | 1 |
p.M168V | STAD | 1 |
p.E946Q | BLCA | 1 |
p.W820C | SARC | 1 |
p.E503K | SKCM | 1 |
p.V381I | SKCM | 1 |
p.G480E | SKCM | 1 |
p.G517S | SKCM | 1 |
p.P973L | SKCM | 1 |
p.R484C | ESCA | 1 |
p.G280R | LUSC | 1 |
p.L626V | BLCA | 1 |
p.P236S | KIRC | 1 |
p.R300G | KIRP | 1 |
p.R223I | UCEC | 1 |
p.T666K | ACC | 1 |
p.T796I | STAD | 1 |
p.M1537I | SKCM | 1 |
p.A1788S | GBM | 1 |
p.L467R | SKCM | 1 |
p.E210Q | BLCA | 1 |
p.E962* | CESC | 1 |
p.T99R | GBM | 1 |
p.V797F | UCEC | 1 |
p.E1281K | SKCM | 1 |
p.E923D | STAD | 1 |
p.R734* | LGG | 1 |
p.E1679K | SKCM | 1 |
p.V363I | PRAD | 1 |
p.K1091R | LUAD | 1 |
p.R794W | LUAD | 1 |
p.Y1072* | SKCM | 1 |
p.L1488I | THYM | 1 |
p.P1598A | MESO | 1 |
p.H829Y | SARC | 1 |
p.A1481V | CHOL | 1 |
p.T1568S | LUSC | 1 |
p.L626V | BRCA | 1 |
p.E1288Q | CESC | 1 |
p.R734X | LIHC | 1 |
p.M466L | LUAD | 1 |
p.E696A | COAD | 1 |
p.Q1709E | KIRP | 1 |
p.E559G | SKCM | 1 |
p.L1050I | UCEC | 1 |
p.Q1111H | PAAD | 1 |
p.P1855T | CHOL | 1 |
p.F830L | ESCA | 1 |
p.R232Q | SKCM | 1 |
p.P236Q | SKCM | 1 |
p.K450T | UCEC | 1 |
p.Q1309* | BLCA | 1 |
p.D402E | LUAD | 1 |
p.H620Y | PRAD | 1 |
p.Y1018C | READ | 1 |
p.G417* | LUSC | 1 |
p.E1281V | SKCM | 1 |
p.S89F | SKCM | 1 |
p.G599E | SKCM | 1 |
p.A976V | ESCA | 1 |
p.R1012C | PRAD | 1 |
p.R734Q | COAD | 1 |
p.G863R | HNSC | 1 |
p.G417V | LUSC | 1 |
p.G512* | UCEC | 1 |
p.T318S | COAD | 1 |
p.G702A | HNSC | 1 |
p.V332I | UCEC | 1 |
p.E831K | SKCM | 1 |
p.A1208V | CESC | 1 |
p.T647I | COAD | 1 |
p.Y1671C | BRCA | 1 |
p.D382E | LUAD | 1 |
p.R1070K | KIRC | 1 |
p.H455Y | STAD | 1 |
p.Q1386* | LUAD | 1 |
p.K1091* | KIRC | 1 |
p.G1273E | SKCM | 1 |
p.A695V | UCEC | 1 |
p.V922A | LIHC | 1 |
p.P1628S | HNSC | 1 |
p.F1858S | SKCM | 1 |
p.A1515G | BRCA | 1 |
p.T1852A | UCEC | 1 |
p.E195K | STAD | 1 |
p.G366R | HNSC | 1 |
p.L1327F | SKCM | 1 |
p.R32C | STAD | 1 |
p.H1313Y | SKCM | 1 |
p.Q935P | OV | 1 |
p.V1383E | OV | 1 |
p.E1167K | SKCM | 1 |
p.E995K | SKCM | 1 |
p.E1341K | SKCM | 1 |
p.M277I | GBM | 1 |
p.R368* | UCEC | 1 |
p.S884F | SKCM | 1 |
p.E252D | COAD | 1 |
p.P567T | ACC | 1 |
p.Q847K | THYM | 1 |
p.A1481D | UCEC | 1 |
p.C638W | SKCM | 1 |
p.G1403S | SKCM | 1 |
p.M1537I | KIRP | 1 |
p.S1557L | SKCM | 1 |
p.G1372E | LUAD | 1 |
p.P1475T | ESCA | 1 |
p.H477Y | LUSC | 1 |
p.F1857V | READ | 1 |
p.N1016T | SKCM | 1 |
p.R232X | SKCM | 1 |
p.D298H | BLCA | 1 |
p.S669Y | LUSC | 1 |
p.R232* | SKCM | 1 |
p.D891E | LUSC | 1 |
p.V415M | THYM | 1 |
p.S1774F | SKCM | 1 |
p.M838V | STAD | 1 |
p.Q297K | LUAD | 1 |
p.E252D | UCEC | 1 |
p.V900I | COAD | 1 |
p.L1814P | STAD | 1 |
p.W1216L | OV | 1 |
p.Y717C | GBM | 1 |
p.E211D | STAD | 1 |
p.F813S | LIHC | 1 |
p.K460N | UCEC | 1 |
p.W820X | SKCM | 1 |
p.R792T | COAD | 1 |
p.G512E | GBM | 1 |
p.D395N | LUAD | 1 |
p.R1550X | COAD | 1 |
p.P101L | STAD | 1 |
p.P1768S | SKCM | 1 |
p.V78A | SARC | 1 |
p.G1106A | LUSC | 1 |
p.L472V | ESCA | 1 |
p.G1372W | BLCA | 1 |
p.T99M | STAD | 1 |
p.R734Q | GBM | 1 |
p.P1013L | BRCA | 1 |
p.V1754I | LUSC | 1 |
p.S1706R | LUAD | 1 |
p.K1091T | KIRC | 1 |
p.Q714K | ESCA | 1 |
p.D1541G | UCEC | 1 |
p.D1720N | SKCM | 1 |
p.G1134E | SKCM | 1 |
p.R484C | SKCM | 1 |
p.K1682N | LUAD | 1 |
p.P1210H | UCEC | 1 |
p.S145L | UCEC | 1 |
p.S1308Y | UCEC | 1 |
p.F1582L | LUSC | 1 |
p.P1084L | SKCM | 1 |
p.D215H | CESC | 1 |
p.L544P | SKCM | 1 |
p.V415M | SKCM | 1 |
p.E962D | DLBC | 1 |
p.R232Q | UCEC | 1 |
p.K1071T | LUSC | 1 |
p.W820* | SARC | 1 |
p.R1587K | HNSC | 1 |
p.L726F | SKCM | 1 |
p.S745R | PAAD | 1 |
p.R1316S | LUAD | 1 |
p.E1163K | HNSC | 1 |
p.T1623A | LUAD | 1 |
p.K1091X | KIRC | 1 |
p.H555Y | CESC | 1 |
p.T1187A | BLCA | 1 |
p.D914A | SKCM | 1 |
Top |
TissGeneCNV for NUP210L |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
Top |
TissGeneFusions for NUP210L |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | ChiTaRs | NA | AW966566 | MED9-NUP210L | chr17:17395121 | chr1:154115613 | |
Chimerdb3.0 | FusionScan | UCS | TCGA-N5-A4RA-01A | WHSC1-NUP210L | In-Frame | chr4:1902978 | chr1:153984846 |
TCGAfusionPortal | PRADA | BRCA | TCGA-AR-A2LR-01A | RORA-NUP210L | Out-of-frame | Chr15:61521252 | Chr1:154076686 |
TCGAfusionPortal | PRADA | BRCA | TCGA-B6-A0I1-01A | GATAD2B-NUP210L | 5UTR-CDS | Chr1:153895209 | Chr1:153967656 |
TCGAfusionPortal | PRADA | LUAD | TCGA-44-7660-01A | GATAD2B-NUP210L | 5UTR-CDS | Chr1:153895209 | Chr1:153982597 |
TCGAfusionPortal | PRADA | OV | TCGA-30-1718-01A | GATAD2B-NUP210L | 5UTR-CDS | Chr1:153895209 | Chr1:153965565 |
Top |
TissGeneNet for NUP210L |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
Top |
TissGeneProg for NUP210L |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Top |
TissGeneClin for NUP210L |
TissGeneDrug for NUP210L |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
TissGeneDisease for NUP210L |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |