Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30073478HIVENSG00000068366.21protein_codingACSL4NoNo2182O60488
TVIS30073479HIVENSG00000068366.21protein_codingACSL4NoNo2182O60488
TVIS30073480HIVENSG00000068366.21protein_codingACSL4NoNo2182O60488
TVIS20064599HPVENSG00000068366.21protein_codingACSL4NoNo2182O60488
TVIS44030218HTLV-1ENSG00000068366.21protein_codingACSL4NoNo2182O60488
TVIS44048501HTLV-1ENSG00000068366.21protein_codingACSL4NoNo2182O60488
TCGA Plot Options
Drug Information
GeneACSL4
DrugBank IDDB00159
Drug NameIcosapent
Target IDBE0000996
UniProt IDO60488
Regulation Typeinducer
PubMed IDs12784866; 15108178
CitationsHeimli H, Hollung K, Drevon CA: Eicosapentaenoic acid-induced apoptosis depends on acyl CoA-synthetase. Lipids. 2003 Mar;38(3):263-8.@@Covault J, Pettinati H, Moak D, Mueller T, Kranzler HR: Association of a long-chain fatty acid-CoA ligase 4 gene polymorphism with depression and with enhanced niacin-induced dermal erythema. Am J Med Genet B Neuropsychiatr Genet. 2004 May 15;127B(1):42-7.
GroupsApproved; Nutraceutical
Direct ClassificationLong-chain fatty acids
SMILESCCC=C/CC=C/CC=C/CC=C/CC=C/CCCC(O)=O
PathwaysAlpha Linolenic Acid and Linoleic Acid Metabolism
PharmGKBPA164746077
ChEMBLCHEMBL460026