| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30073478 | HIV | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
| TVIS30073479 | HIV | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
| TVIS30073480 | HIV | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
| TVIS20064599 | HPV | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
| TVIS44030218 | HTLV-1 | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
| TVIS44048501 | HTLV-1 | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ACSL4 |
|---|---|
| DrugBank ID | DB00197 |
| Drug Name | Troglitazone |
| Target ID | BE0000996 |
| UniProt ID | O60488 |
| Regulation Type | inhibitor |
| PubMed IDs | 11319222; 12147264; 11319232 |
| Citations | Kim JH, Lewin TM, Coleman RA: Expression and characterization of recombinant rat Acyl-CoA synthetases 1, 4, and 5. Selective inhibition by triacsin C and thiazolidinediones. J Biol Chem. 2001 Jul 6;276(27):24667-73. Epub 2001 Apr 23.@@Lewin TM, Van Horn CG, Krisans SK, Coleman RA: Rat liver acyl-CoA synthetase 4 is a peripheral-membrane protein located in two distinct subcellular organelles, peroxisomes, and mitochondrial-associated membrane. Arch Biochem Biophys. 2002 Aug 15;404(2):263-70.@@Lewin TM, Kim JH, Granger DA, Vance JE, Coleman RA: Acyl-CoA synthetase isoforms 1, 4, and 5 are present in different subcellular membranes in rat liver and can be inhibited independently. J Biol Chem. 2001 Jul 6;276(27):24674-9. Epub 2001 Apr 23. |
| Groups | Approved; Investigational; Withdrawn |
| Direct Classification | 1-benzopyrans |
| SMILES | CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O |
| Pathways | |
| PharmGKB | PA451799 |
| ChEMBL | CHEMBL408 |
