| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30073478 | HIV | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
| TVIS30073479 | HIV | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
| TVIS30073480 | HIV | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
| TVIS20064599 | HPV | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
| TVIS44030218 | HTLV-1 | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
| TVIS44048501 | HTLV-1 | ENSG00000068366.21 | protein_coding | ACSL4 | No | No | 2182 | O60488 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ACSL4 |
|---|---|
| DrugBank ID | DB00412 |
| Drug Name | Rosiglitazone |
| Target ID | BE0000996 |
| UniProt ID | O60488 |
| Regulation Type | inhibitor |
| PubMed IDs | 17259370 |
| Citations | Askari B, Kanter JE, Sherrid AM, Golej DL, Bender AT, Liu J, Hsueh WA, Beavo JA, Coleman RA, Bornfeldt KE: Rosiglitazone inhibits acyl-CoA synthetase activity and fatty acid partitioning to diacylglycerol and triacylglycerol via a peroxisome proliferator-activated receptor-gamma-independent mechanism in human arterial smooth muscle cells and macrophages. Diabetes. 2007 Apr;56(4):1143-52. Epub 2007 Jan 26. |
| Groups | Approved; Investigational |
| Direct Classification | Phenol ethers |
| SMILES | CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1 |
| Pathways | Rosiglitazone Metabolism Pathway |
| PharmGKB | PA451283 |
| ChEMBL | CHEMBL121 |
