| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10058045 | HBV | ENSG00000164305.20 | protein_coding | CASP3 | No | No | 836 | P42574 |
| TVIS10058044 | HBV | ENSG00000164305.20 | protein_coding | CASP3 | No | No | 836 | P42574 |
| TVIS30008701 | HIV | ENSG00000164305.20 | protein_coding | CASP3 | No | No | 836 | P42574 |
| TVIS30008702 | HIV | ENSG00000164305.20 | protein_coding | CASP3 | No | No | 836 | P42574 |
| TVIS30061613 | HIV | ENSG00000164305.20 | protein_coding | CASP3 | No | No | 836 | P42574 |
| TVIS30061614 | HIV | ENSG00000164305.20 | protein_coding | CASP3 | No | No | 836 | P42574 |
| TVIS44019305 | HTLV-1 | ENSG00000164305.20 | protein_coding | CASP3 | No | No | 836 | P42574 |
| TVIS44019306 | HTLV-1 | ENSG00000164305.20 | protein_coding | CASP3 | No | No | 836 | P42574 |
| TVIS44004779 | HTLV-1 | ENSG00000164305.20 | protein_coding | CASP3 | No | No | 836 | P42574 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CASP3 |
|---|---|
| DrugBank ID | DB00282 |
| Drug Name | Pamidronic acid |
| Target ID | BE0001162 |
| UniProt ID | P42574 |
| Regulation Type | activator |
| PubMed IDs | 16298452; 12177810 |
| Citations | Wada A, Fukui K, Sawai Y, Imanaka K, Kiso S, Tamura S, Shimomura I, Hayashi N: Pamidronate induced anti-proliferative, apoptotic, and anti-migratory effects in hepatocellular carcinoma. J Hepatol. 2006 Jan;44(1):142-50. doi: 10.1016/j.jhep.2005.09.022. Epub 2005 Nov 9.@@Riebeling C, Forsea AM, Raisova M, Orfanos CE, Geilen CC: The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro. Br J Cancer. 2002 Jul 29;87(3):366-71. |
| Groups | Approved |
| Direct Classification | Bisphosphonates |
| SMILES | NCCC(O)(P(O)(O)=O)P(O)(O)=O |
| Pathways | Pamidronate Action Pathway |
| PharmGKB | PA450767 |
| ChEMBL | CHEMBL834 |
