Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10007745HBVENSG00000144891.19protein_codingAGTR1NoNo185A0A0A0MSE3
D3DNG8
P30556
Q53YY0
Q6NUP5
TVIS10041838HBVENSG00000144891.19protein_codingAGTR1NoNo185A0A0A0MSE3
D3DNG8
P30556
Q53YY0
Q6NUP5
TCGA Plot Options
Drug Information
GeneAGTR1
DrugBank IDDB01349
Drug NameTasosartan
Target IDBE0000062
UniProt IDP30556
Regulation Typeantagonist
PubMed IDs12113820; 11683476; 11046101; 11752352
CitationsElokdah HM, Friedrichs GS, Chai SY, Harrison BL, Primeau J, Chlenov M, Crandall DL: Novel human metabolites of the angiotensin-II antagonist tasosartan and their pharmacological effects. Bioorg Med Chem Lett. 2002 Aug 5;12(15):1967-71.@@Unger T: Pharmacology of AT1-receptor blockers. Blood Press Suppl. 2001;(3):5-10.@@Maillard MP, Rossat J, Brunner HR, Burnier M: Tasosartan, enoltasosartan, and angiotensin II receptor blockade: the confounding role of protein binding. J Pharmacol Exp Ther. 2000 Nov;295(2):649-54.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.
GroupsExperimental
Direct ClassificationBiphenyls and derivatives
SMILESCC1=NC(C)=C2CCC(=O)N(CC3=CC=C(C=C3)C3=CC=CC=C3C3=NNN=N3)C2=N1
Pathways
PharmGKBPA164769057
ChEMBLCHEMBL432162