| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10007745 | HBV | ENSG00000144891.19 | protein_coding | AGTR1 | No | No | 185 | A0A0A0MSE3 D3DNG8 P30556 Q53YY0 Q6NUP5 |
| TVIS10041838 | HBV | ENSG00000144891.19 | protein_coding | AGTR1 | No | No | 185 | A0A0A0MSE3 D3DNG8 P30556 Q53YY0 Q6NUP5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AGTR1 |
|---|---|
| DrugBank ID | DB01342 |
| Drug Name | Forasartan |
| Target ID | BE0000062 |
| UniProt ID | P30556 |
| Regulation Type | antagonist |
| PubMed IDs | 11569611; 8981065; 9156352; 11752352 |
| Citations | Tokunaga R, Kushiku K, Yamada K, Yamada H, Furukawa T: Possible involvement of calcium-calmodulin pathways in the positive chronotropic response to angiotensin II on the canine cardiac sympathetic ganglia. Jpn J Pharmacol. 2001 Aug;86(4):381-9.@@Usune S, Furukawa T: Effects of SC-52458, a new nonpeptide angiotensin II receptor antagonist, on increase in cytoplasmic Ca2+ concentrations and contraction induced by angiotensin II and K(+)-depolarization in guinea-pig taenia coli. Gen Pharmacol. 1996 Oct;27(7):1179-85.@@Hagmann M, Nussberger J, Naudin RB, Burns TS, Karim A, Waeber B, Brunner HR: SC-52458, an orally active angiotensin II-receptor antagonist: inhibition of blood pressure response to angiotensin II challenges and pharmacokinetics in normal volunteers. J Cardiovasc Pharmacol. 1997 Apr;29(4):444-50.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Experimental |
| Direct Classification | Phenylpyridines |
| SMILES | CCCCC1=NN(CC2=CN=C(C=C2)C2=CC=CC=C2C2=NNN=N2)C(CCCC)=N1 |
| Pathways | Forasartan Action Pathway |
| PharmGKB | PA164776845 |
| ChEMBL | CHEMBL315021 |
