| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20009981 | HPV | ENSG00000006283.18 | protein_coding | CACNA1G | No | No | 8913 | O43497 |
| TVIS44042288 | HTLV-1 | ENSG00000006283.18 | protein_coding | CACNA1G | No | No | 8913 | O43497 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1G |
|---|---|
| DrugBank ID | DB05246 |
| Drug Name | Methsuximide |
| Target ID | BE0000483 |
| UniProt ID | O43497 |
| Regulation Type | inhibitor |
| PubMed IDs | 11641441; 2545161; 19005061; 11274992 |
| Citations | Gomora JC, Daud AN, Weiergraber M, Perez-Reyes E: Block of cloned human T-type calcium channels by succinimide antiepileptic drugs. Mol Pharmacol. 2001 Nov;60(5):1121-32.@@Coulter DA, Huguenard JR, Prince DA: Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons. Ann Neurol. 1989 Jun;25(6):582-93.@@Wang G, Thompson SM: Maladaptive homeostatic plasticity in a rodent model of central pain syndrome: thalamic hyperexcitability after spinothalamic tract lesions. J Neurosci. 2008 Nov 12;28(46):11959-69. doi: 10.1523/JNEUROSCI.3296-08.2008.@@Matthews EA, Dickenson AH: Effects of ethosuximide, a T-type Ca(2+) channel blocker, on dorsal horn neuronal responses in rats. Eur J Pharmacol. 2001 Mar;415(2-3):141-9. |
| Groups | Approved |
| Direct Classification | Phenylpyrrolidines |
| SMILES | CN1C(=O)CC(C)(C1=O)C1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA164743145 |
| ChEMBL | CHEMBL697 |
