Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20009981HPVENSG00000006283.18protein_codingCACNA1GNoNo8913O43497
TVIS44042288HTLV-1ENSG00000006283.18protein_codingCACNA1GNoNo8913O43497
TCGA Plot Options
Drug Information
GeneCACNA1G
DrugBank IDDB01115
Drug NameNifedipine
Target IDBE0008716
UniProt IDQ9P0X4
Regulation Typeinhibitor
PubMed IDs16899990; 28611661
CitationsLee TS, Kaku T, Takebayashi S, Uchino T, Miyamoto S, Hadama T, Perez-Reyes E, Ono K: Actions of mibefradil, efonidipine and nifedipine block of recombinant T- and L-type Ca channels with distinct inhibitory mechanisms. Pharmacology. 2006;78(1):11-20. Epub 2006 Aug 7.@@Godfraind T: Discovery and Development of Calcium Channel Blockers. Front Pharmacol. 2017 May 29;8:286. doi: 10.3389/fphar.2017.00286. eCollection 2017.
GroupsApproved
Direct ClassificationDihydropyridinecarboxylic acids and derivatives
SMILESCOC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC
PathwaysNifedipine Action Pathway
PharmGKBPA450631
ChEMBLCHEMBL193