| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44021745 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
| TVIS44014146 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
| TVIS44000462 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
| TVIS44021746 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
| TVIS44033264 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
| TVIS44037432 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHRM3 |
|---|---|
| DrugBank ID | DB00363 |
| Drug Name | Clozapine |
| Target ID | BE0000045 |
| UniProt ID | P20309 |
| Regulation Type | antagonist |
| PubMed IDs | 17848919; 33647377 |
| Citations | Nasrallah HA: Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles. Mol Psychiatry. 2008 Jan;13(1):27-35. Epub 2007 Sep 11.@@Foster DJ, Bryant ZK, Conn PJ: Targeting muscarinic receptors to treat schizophrenia. Behav Brain Res. 2021 May 7;405:113201. doi: 10.1016/j.bbr.2021.113201. Epub 2021 Feb 26. |
| Groups | Approved |
| Direct Classification | Dibenzodiazepines |
| SMILES | CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA449061 |
| ChEMBL | CHEMBL42 |
