| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44021745 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
| TVIS44014146 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
| TVIS44000462 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
| TVIS44021746 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
| TVIS44033264 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
| TVIS44037432 | HTLV-1 | ENSG00000133019.12 | protein_coding | CHRM3 | No | No | 1131 | P20309 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHRM3 |
|---|---|
| DrugBank ID | DB00940 |
| Drug Name | Methantheline |
| Target ID | BE0000045 |
| UniProt ID | P20309 |
| Regulation Type | |
| PubMed IDs | 17922784; 29938305 |
| Citations | Abrams P, Andersson KE: Muscarinic receptor antagonists for overactive bladder. BJU Int. 2007 Nov;100(5):987-1006. doi: 10.1111/j.1464-410X.2007.07205.x.@@Irmen M, Holze J, Bodefeld T, Trankle C: Characterization of methanthelinium binding and function at human M1-M5 muscarinic acetylcholine receptors. Naunyn Schmiedebergs Arch Pharmacol. 2018 Oct;391(10):1037-1052. doi: 10.1007/s00210-018-1525-1. Epub 2018 Jun 24. |
| Groups | Approved; Investigational |
| Direct Classification | Xanthenes |
| SMILES | CC[N+](C)(CC)CCOC(=O)C1C2=CC=CC=C2OC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA164747037 |
| ChEMBL | CHEMBL1201264 |
