Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44021745HTLV-1ENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS44014146HTLV-1ENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS44000462HTLV-1ENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS44021746HTLV-1ENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS44033264HTLV-1ENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS44037432HTLV-1ENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TCGA Plot Options
Drug Information
GeneCHRM3
DrugBank IDDB00387
Drug NameProcyclidine
Target IDBE0000045
UniProt IDP20309
Regulation Typeantagonist
PubMed IDs20624420; 1426023
CitationsMyhrer T: Identification of neuronal target areas for nerve agents and specification of receptors for pharmacological treatment. Neurotoxicology. 2010 Dec;31(6):629-38. doi: 10.1016/j.neuro.2010.07.002. Epub 2010 Jul 17.@@Waelbroeck M, Camus J, Tastenoy M, Mutschler E, Strohmann C, Tacke R, Schjelderup L, Aasen A, Lambrecht G, Christophe J: Stereoselective interaction of procyclidine, hexahydro-difenidol, hexbutinol and oxyphencyclimine, and of related antagonists, with four muscarinic receptors. Eur J Pharmacol. 1992 Sep 1;227(1):33-42.
GroupsApproved
Direct ClassificationAralkylamines
SMILESOC(CCN1CCCC1)(C1CCCCC1)C1=CC=CC=C1
Pathways
PharmGKBPA164784001
ChEMBLCHEMBL86715