| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20000082 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20007360 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20027601 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20027588 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20015105 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20019576 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20019577 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20030913 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS44013030 | HTLV-1 | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FGFR3 |
|---|---|
| DrugBank ID | DB15149 |
| Drug Name | Futibatinib |
| Target ID | BE0002133 |
| UniProt ID | P22607 |
| Regulation Type | inhibitor |
| PubMed IDs | 32973082 |
| Citations | Sootome H, Fujita H, Ito K, Ochiiwa H, Fujioka Y, Ito K, Miura A, Sagara T, Ito S, Ohsawa H, Otsuki S, Funabashi K, Yashiro M, Matsuo K, Yonekura K, Hirai H: Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors. Cancer Res. 2020 Nov 15;80(22):4986-4997. doi: 10.1158/0008-5472.CAN-19-2568. Epub 2020 Sep 24. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | COC1=CC(=CC(OC)=C1)C#CC1=NN([C@H]2CCN(C2)C(=O)C=C)C2=C1C(N)=NC=N2 |
| Pathways | |
| PharmGKB | PA166293381 |
| ChEMBL | CHEMBL3701238 |
