| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20000082 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20007360 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20027601 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20027588 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20015105 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20019576 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20019577 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20030913 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS44013030 | HTLV-1 | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FGFR3 |
|---|---|
| DrugBank ID | DB15102 |
| Drug Name | Pemigatinib |
| Target ID | BE0002133 |
| UniProt ID | P22607 |
| Regulation Type | inhibitor |
| PubMed IDs | 32315352 |
| Citations | Liu PCC, Koblish H, Wu L, Bowman K, Diamond S, DiMatteo D, Zhang Y, Hansbury M, Rupar M, Wen X, Collier P, Feldman P, Klabe R, Burke KA, Soloviev M, Gardiner C, He X, Volgina A, Covington M, Ruggeri B, Wynn R, Burn TC, Scherle P, Yeleswaram S, Yao W, Huber R, Hollis G: INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models. PLoS One. 2020 Apr 21;15(4):e0231877. doi: 10.1371/journal.pone.0231877. eCollection 2020. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | CCN1C(=O)N(CC2=CN=C3NC(CN4CCOCC4)=CC3=C12)C1=C(F)C(OC)=CC(OC)=C1F |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL4297522 |
