| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20000082 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20007360 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20027601 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20027588 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20015105 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20019576 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20019577 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS20030913 | HPV | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
| TVIS44013030 | HTLV-1 | ENSG00000068078.20 | protein_coding | FGFR3 | Yes | No | 2261 | P22607 Q0IJ44 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FGFR3 |
|---|---|
| DrugBank ID | DB09079 |
| Drug Name | Nintedanib |
| Target ID | BE0002133 |
| UniProt ID | P22607 |
| Regulation Type | inhibitor |
| PubMed IDs | 18559524; 31016670 |
| Citations | Hilberg F, Roth GJ, Krssak M, Kautschitsch S, Sommergruber W, Tontsch-Grunt U, Garin-Chesa P, Bader G, Zoephel A, Quant J, Heckel A, Rettig WJ: BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy. Cancer Res. 2008 Jun 15;68(12):4774-82. doi: 10.1158/0008-5472.CAN-07-6307.@@Wind S, Schmid U, Freiwald M, Marzin K, Lotz R, Ebner T, Stopfer P, Dallinger C: Clinical Pharmacokinetics and Pharmacodynamics of Nintedanib. Clin Pharmacokinet. 2019 Sep;58(9):1131-1147. doi: 10.1007/s40262-019-00766-0. |
| Groups | Approved |
| Direct Classification | Indolecarboxylic acids |
| SMILES | COC(=O)C1=CC=C2C(NC(=O)C2=C(/NC2=CC=C(C=C2)N(C)C(=O)CN2CCN(C)CC2)C2=CC=CC=C2)=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL502835 |
