| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20026611 | HPV | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS20023629 | HPV | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS20024834 | HPV | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS44027440 | HTLV-1 | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS44047554 | HTLV-1 | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS44051325 | HTLV-1 | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TRPV1 |
|---|---|
| DrugBank ID | DB09061 |
| Drug Name | Cannabidiol |
| Target ID | BE0001023 |
| UniProt ID | Q8NER1 |
| Regulation Type | activator |
| PubMed IDs | 26264914; 11606325; 25029033; 21175579 |
| Citations | Ibeas Bih C, Chen T, Nunn AV, Bazelot M, Dallas M, Whalley BJ: Molecular Targets of Cannabidiol in Neurological Disorders. Neurotherapeutics. 2015 Oct;12(4):699-730. doi: 10.1007/s13311-015-0377-3.@@Bisogno T, Hanus L, De Petrocellis L, Tchilibon S, Ponde DE, Brandi I, Moriello AS, Davis JB, Mechoulam R, Di Marzo V: Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br J Pharmacol. 2001 Oct;134(4):845-52. doi: 10.1038/sj.bjp.0704327.@@Iannotti FA, Hill CL, Leo A, Alhusaini A, Soubrane C, Mazzarella E, Russo E, Whalley BJ, Di Marzo V, Stephens GJ: Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability. ACS Chem Neurosci. 2014 Nov 19;5(11):1131-41. doi: 10.1021/cn5000524. Epub 2014 Jul 29.@@De Petrocellis L, Ligresti A, Moriello AS, Allara M, Bisogno T, Petrosino S, Stott CG, Di Marzo V: Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. Br J Pharmacol. 2011 Aug;163(7):1479-94. doi: 10.1111/j.1476-5381.2010.01166.x. |
| Groups | Approved; Investigational |
| Direct Classification | Aromatic monoterpenoids |
| SMILES | CCCCCC1=CC(O)=C([C@@H]2C=C(C)CC[C@H]2C(C)=C)C(O)=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL190461 |
