| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20026611 | HPV | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS20023629 | HPV | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS20024834 | HPV | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS44027440 | HTLV-1 | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS44047554 | HTLV-1 | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS44051325 | HTLV-1 | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TRPV1 |
|---|---|
| DrugBank ID | DB11324 |
| Drug Name | Nonivamide |
| Target ID | BE0001023 |
| UniProt ID | Q8NER1 |
| Regulation Type | agonist |
| PubMed IDs | 21343315; 6202305; 23929722 |
| Citations | Thomas KC, Ethirajan M, Shahrokh K, Sun H, Lee J, Cheatham TE 3rd, Yost GS, Reilly CA: Structure-activity relationship of capsaicin analogs and transient receptor potential vanilloid 1-mediated human lung epithelial cell toxicity. J Pharmacol Exp Ther. 2011 May;337(2):400-10. doi: 10.1124/jpet.110.178491. Epub 2011 Feb 22.@@Skofitsch G, Donnerer J, Lembeck F: Comparison of nonivamide and capsaicin with regard to their pharmacokinetics and effects on sensory neurons. Arzneimittelforschung. 1984;34(2):154-6.@@Rohm B, Holik AK, Somoza MM, Pignitter M, Zaunschirm M, Ley JP, Krammer GE, Somoza V: Nonivamide, a capsaicin analog, increases dopamine and serotonin release in SH-SY5Y cells via a TRPV1-independent pathway. Mol Nutr Food Res. 2013 Nov;57(11):2008-18. doi: 10.1002/mnfr.201200846. Epub 2013 Aug 9. |
| Groups | Investigational |
| Direct Classification | Methoxyphenols |
| SMILES | CCCCCCCCC(=O)NCC1=CC(OC)=C(O)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL75124 |
