| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20026611 | HPV | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS20023629 | HPV | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS20024834 | HPV | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS44027440 | HTLV-1 | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS44047554 | HTLV-1 | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
| TVIS44051325 | HTLV-1 | ENSG00000196689.13 | protein_coding | TRPV1 | No | No | 7442 | Q8NER1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TRPV1 |
|---|---|
| DrugBank ID | DB14050 |
| Drug Name | Cannabidivarin |
| Target ID | BE0001023 |
| UniProt ID | Q8NER1 |
| Regulation Type | agonist |
| PubMed IDs | 22970845; 25029033; 29290836; 29842819; 21175579 |
| Citations | Hill AJ, Mercier MS, Hill TD, Glyn SE, Jones NA, Yamasaki Y, Futamura T, Duncan M, Stott CG, Stephens GJ, Williams CM, Whalley BJ: Cannabidivarin is anticonvulsant in mouse and rat. Br J Pharmacol. 2012 Dec;167(8):1629-42. doi: 10.1111/j.1476-5381.2012.02207.x.@@Iannotti FA, Hill CL, Leo A, Alhusaini A, Soubrane C, Mazzarella E, Russo E, Whalley BJ, Di Marzo V, Stephens GJ: Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability. ACS Chem Neurosci. 2014 Nov 19;5(11):1131-41. doi: 10.1021/cn5000524. Epub 2014 Jul 29.@@Capasso A: Do Cannabinoids Confer Neuroprotection Against Epilepsy? An Overview. Open Neurol J. 2017 Dec 18;11:61-73. doi: 10.2174/1874205X01711010061. eCollection 2017.@@Ruzic Zecevic D, Folic M, Tantoush Z, Radovanovic M, Babic G, Jankovic SM: Investigational cannabinoids in seizure disorders, what have we learned thus far? Expert Opin Investig Drugs. 2018 Jun 6:1-7. doi: 10.1080/13543784.2018.1482275.@@De Petrocellis L, Ligresti A, Moriello AS, Allara M, Bisogno T, Petrosino S, Stott CG, Di Marzo V: Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. Br J Pharmacol. 2011 Aug;163(7):1479-94. doi: 10.1111/j.1476-5381.2010.01166.x. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | [H][C@]1(CCC(C)=C[C@H]1C1=C(O)C=C(CCC)C=C1O)C(C)=C |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2387742 |
