| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20009341 | HPV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS20068329 | HPV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS44006869 | HTLV-1 | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS44004202 | HTLV-1 | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HDAC1 |
|---|---|
| DrugBank ID | DB06603 |
| Drug Name | Panobinostat |
| Target ID | BE0008667 |
| UniProt ID | Q9UKV0 |
| Regulation Type | inhibitor |
| PubMed IDs | 17455259; 17145876; 26848406 |
| Citations | Beckers T, Burkhardt C, Wieland H, Gimmnich P, Ciossek T, Maier T, Sanders K: Distinct pharmacological properties of second generation HDAC inhibitors with the benzamide or hydroxamate head group. Int J Cancer. 2007 Sep 1;121(5):1138-48.@@Geng L, Cuneo KC, Fu A, Tu T, Atadja PW, Hallahan DE: Histone deacetylase (HDAC) inhibitor LBH589 increases duration of gamma-H2AX foci and confines HDAC4 to the cytoplasm in irradiated non-small cell lung cancer. Cancer Res. 2006 Dec 1;66(23):11298-304.@@Favreau AJ, McGlauflin RE, Duarte CW, Sathyanarayana P: miR-199b, a novel tumor suppressor miRNA in acute myeloid leukemia with prognostic implications. Exp Hematol Oncol. 2016 Feb 3;5:4. doi: 10.1186/s40164-016-0033-6. eCollection 2015. |
| Groups | Approved; Investigational |
| Direct Classification | Tryptamines and derivatives |
| SMILES | CC1=C(CCNCC2=CC=C(C=CC(=O)NO)C=C2)C2=CC=CC=C2N1 |
| Pathways | |
| PharmGKB | PA166161307 |
| ChEMBL | CHEMBL483254 |
