Target Gene Table ▼
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10013412HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013413HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013414HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013415HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013416HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013417HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013418HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013419HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013420HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10019801HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TCGA Plot Options ▼
Drug Information ▼
GeneCHRM3
DrugBank IDDB00383
Drug NameOxyphencyclimine
Target IDBE0000045
UniProt IDP20309
Regulation Typeantagonist
PubMed IDs17139284; 17016423; 1426023; 3247303
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Waelbroeck M, Camus J, Tastenoy M, Mutschler E, Strohmann C, Tacke R, Schjelderup L, Aasen A, Lambrecht G, Christophe J: Stereoselective interaction of procyclidine, hexahydro-difenidol, hexbutinol and oxyphencyclimine, and of related antagonists, with four muscarinic receptors. Eur J Pharmacol. 1992 Sep 1;227(1):33-42.@@Schjelderup L, Kozlowski MR, Weissman A, Aasen AJ: Antimuscarinic effects of (R)- and (S)- oxyphencyclimine hydrochloride. Pharm Res. 1988 Apr;5(4):236-7.
GroupsApproved
Direct ClassificationHydropyrimidines
SMILESCN1CCCN=C1COC(=O)C(O)(C1CCCCC1)C1=CC=CC=C1
Pathways
PharmGKBPA164776910
ChEMBLCHEMBL1495